Sekonder hiperparatiroidizm ve kalsimimetikler

OPTIMA:Cinacalcet&Vit D ilişkisiOPTIMAStandard tedavin=123Bazal23.haftaBazalCinacalcetn=25223.haftaOrtalama2.62.72.21.7MedianOrtalama dozdeğişikliği2.0-2.0+3%2.0Patients prescribed vitamin D at baseline are included. Vitamin D dose was calculated as amultiple of the protocol-defined minimum dose.-1.1-22%Minimum dose: IV calcitriol: 0.5 mcg TIW, IV alfacalcidol: 1 mcg TIW, IV paricalcitol: 2 mcgTIW, oral calcitriol: 0.25 mcg TIW, oral alfacalcidol: 0.25 mcg per day.Messa P et al. submitted for publication 2007 (data on file)