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Case study: improving industrial enzymeResults after L-Shuffling and HTS1000900Inactive 26% < WT 34% ≈ WT12% > WT 28 %Relative activity %8007006005004003002001000Parental genesEurobio 2009 LilleNumber of clones screened
Other case studyImprove specific activity 2 L-Shuffling rounds using three homologous genes (70%)Set up of the HTS assay (colorimetric assay)Screening of 25 000 clones per roundEurobio 2009 Lille
Page 2 and 3: In- and out-sourcing management for
Page 4 and 5: Protéus, world expert in proteinsP
Page 6 and 7: Integrated PlatformEurobio 2009 Lil
Page 8 and 9: Industrial partnershipsHealthcareCh
Page 10 and 11: From concept to industrial products
Page 12 and 13: Proteus Business ChainBibliographic
Page 14 and 15: Protéus biodiversityVery large div
Page 16 and 17: What does screening result into ?Bi
Page 20: ResultsGenetic diversityVPAGTPWGTAY
Page 23 and 24: Host library - Prokaryotes• Multi
Page 25 and 26: Key deliverable from ProtéusBiodiv
Page 27 and 28: In- and out-sourcing management for
Page 29 and 30: Relationship Between Owners of Tech
Page 31 and 32: The Take Away MessageNo single biot

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