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Forsknings- og Innovationsberetning 2011 - Forskningens Hus

Forsknings- og Innovationsberetning 2011 - Forskningens Hus

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Publikationer<br />

Forskning<br />

Ph.d.-afhandling<br />

1. Ernst A. Genetic risk factors of inflammatory<br />

bowel disease: with special<br />

emphasis on CARD15 and the biotransformation<br />

enzymes: GSTM1,<br />

GSTT1, GSTP1, NAT2 and mEH. Aalborg,<br />

Denmark: Aalborg Universitetsforlag;<br />

<strong>2011</strong> pp. 58.<br />

2. Tuckuviene R. Venous and arterial<br />

thromboembolism in children and<br />

adolscents in Denmark 1994-2006.<br />

Aarhus, Denmark: Aarhus Universitet;<br />

<strong>2011</strong><br />

Artikel, peer-reviewed<br />

1. Thomassen M, Pedersen IS, V<strong>og</strong>el I,<br />

Hansen TV, Brasch-Andersen C, Brasen<br />

CL, Crüger D, Sunde L, Nielsen FC,<br />

Jensen UB, Bisgaard ML, Borg A, Gerdes<br />

AM, Kruse TA. A BRCA2 mutation<br />

incorrectly mapped in the original BRCA2<br />

reference sequence, is a common West<br />

Danish founder mutation disrupting mRNA<br />

splicing. Breast Cancer Res Treat<br />

<strong>2011</strong>;128(1):179-85.<br />

2. Alzuhairi KS, Hjortshøj S, Kristensen<br />

SR, Ravkilde J. A third troponin T blood<br />

sample is not cost-effective in patients with<br />

suspected non-ST segment elevation acute<br />

coronary syndrome. Scand J Clin Lab<br />

Invest <strong>2011</strong>;71(2):117-22.<br />

3. Andersen V, Ernst A, Sventoraityte J,<br />

Kupcinskas L, Jacobsen BA, Krarup<br />

HB, V<strong>og</strong>el U, Jonaitis L, Denapiene G,<br />

Kiudelis G, Balschun T, Franke A. Assessment<br />

of heter<strong>og</strong>eneity between European<br />

Populations: a Baltic and Danish replication<br />

case-control study of SNPs from a recent<br />

European ulcerative colitis genome wide<br />

association study. BMC Med Genet<br />

<strong>2011</strong>;12(1):139.<br />

4. Arnberg K, Ostergård M, Madsen A,<br />

Krarup HB, Michaelsen K, Mølgaard C.<br />

Associations between vitamin D status in<br />

infants and blood lipids, body mass index and<br />

waist circumference. Acta Paediatr<br />

<strong>2011</strong>;100(9):1244-8.<br />

5. Bernstein IT, Lindorff-Larsen K, Timshel<br />

S, Brandt CA, Dinesen B, Fenger<br />

M, Gerdes AM, Iversen LH, Madsen<br />

MR, Okkels H, Sunde L, Rahr HB,<br />

Wikman FP, Rossing N. Biomedical<br />

informatics as support to individual healthcare<br />

in hereditary colon cancer: the Danish<br />

HNPCC system. Hum Mutat<br />

<strong>2011</strong>;32(5):551-6.<br />

6. Klarskov L, Holck S, Bernstein I, Okkels<br />

H, Rambech E, Baldetorp B, Nilbert M.<br />

Challenges in the Identification of MSH6-<br />

Associated Colorectal Cancer: Rectal Location,<br />

Less Typical Histol<strong>og</strong>y, and a Subset<br />

With Retained Mismatch Repair Function.<br />

Am J Surg Pathol <strong>2011</strong>;35(9):1391-9.<br />

7. Ernst A, Andersen V, Ostergaard M,<br />

Jacobsen BA, Pedersen IS, Drewes AM,<br />

64<br />

Okkels H, Krarup HB. Common polymorphisms<br />

in the microsomal epoxide hydrolase<br />

and N-acetyltransferase 2 genes in association<br />

with inflammatory bowel disease in the<br />

Danish population. Eur J Gastroenterol<br />

Hepatol <strong>2011</strong>;23(3):269-74.<br />

8. Clausen LN, Weis N, Schønning K,<br />

Fenger M, Krarup H, Bukh J, Benfield T.<br />

Correlates of spontaneous clearance of<br />

hepatitis C virus in a Danish human immunodeficiency<br />

virus type 1 cohort. Scand J<br />

Infect Dis <strong>2011</strong>;43(10):798-803.<br />

9. Andersen V, Nimmo E, Krarup HB,<br />

Drummond H, Christensen J, Ho GT,<br />

Østergaard M, Ernst A, Lees C, Jacobsen<br />

BA, Satsangi J, V<strong>og</strong>el U. Cyclooxygenase-2<br />

(COX-2) polymorphisms and risk of<br />

inflammatory bowel disease in a Scottish and<br />

Danish case-control study. Inflamm Bowel<br />

Dis <strong>2011</strong>;17(4):937-46.<br />

10. Faurholt-Jepsen D, Range N, Praygod<br />

G, Jeremiah K, Faurholt-Jepsen M,<br />

Aabye MG, Changalucha J, Christensen<br />

DL, Pipper CB, Krarup H, Witte DR,<br />

Andersen AB, Friis H. Diabetes is a risk<br />

factor for pulmonary tuberculosis: a casecontrol<br />

study from mwanza, Tanzania. PLoS<br />

One <strong>2011</strong>;6(8):e24215.<br />

11. Hansen N, Obel N, Christensen PB,<br />

Kjær M, Laursen AL, Krarup HB, Møller<br />

A, Schlichting P, Bukh J, Weis N,<br />

[the Danish Database for Hepatitis B<br />

and C (DANHEP)- group] . Effectiveness<br />

of treatment with pegylated interferon and<br />

ribavirin in an unselected population of<br />

patients with chronic hepatitis C: A Danish<br />

nationwide cohort study. BMC Infect Dis<br />

<strong>2011</strong>;11(1):177-e8.<br />

12. Rix M, Laurberg P, Porzig C, Kristensen<br />

SR. Elevated thyroid-stimulating hormone<br />

level in a euthyroid neonate caused by macro<br />

thyrotropin-IgG complex. Acta Paediatr<br />

<strong>2011</strong>;100(9):e135-7.<br />

13. Shim J, Handberg A, Ostergren C, Falk<br />

E, Bentzon JF. Genetic susceptibility of the<br />

arterial wall is an important determinant of<br />

atherosclerosis in C57BL/6 and FVB/N<br />

mouse strains. Arterioscler Thromb Vasc<br />

Biol <strong>2011</strong>;31(8):1814-20.<br />

14. Krarup H, Andersen S, Madsen PH,<br />

Christensen PB, Laursen AL, Bentzen-<br />

Petersen A, Møller JM, Weis N, [the<br />

DANHEP group] . HBeAg and not genotypes<br />

predicts viral load in patients with hepatitis<br />

B in Denmark: A nationwide cohort<br />

study. Scand J Gastroenterol<br />

<strong>2011</strong>;46(12):1484-91.<br />

15. Martinez-Martinez I, Ordonez A, Pedersen<br />

S, de la Morena-Barrio ME,<br />

Navarro-Fernández J, Kristensen SR,<br />

Minano A, Padilla J, Vicente V, Corral J.<br />

Heparin affinity of factor VIIa: implications<br />

on the physiol<strong>og</strong>ical inhibition by antithrombin<br />

and clearance of recombinant factor VIIa.<br />

Thromb Res <strong>2011</strong>;127(2):154-60.<br />

16. Omland LH, Jepsen P, Krarup H,<br />

Schønning K, Lind B, Kromann-Andersen<br />

H, Homburg KM, Christensen PB,<br />

Sørensen HT, Obel N, [DANVIR Cohort<br />

Study] . Increased Mortality Among Persons<br />

Infected with Hepatitis C Virus. Clin Gastroenterol<br />

Hepatol <strong>2011</strong>;9(1):71-8.<br />

17. Clausen LN, Weis N, Astvad K, Schønning<br />

K, Fenger M, Krarup HB, Bukh J,<br />

Benfield T. Interleukin-28B polymorphisms<br />

are associated with hepatitis C virus clearance<br />

and viral load in a HIV-1-infected<br />

cohort. J Viral Hepat <strong>2011</strong>;18(4):e66-<br />

74.<br />

18. Verder H, Ebbesen F, Brandt J, Dahl M,<br />

Esberg G, Eschen C, Grytter C, Kroner<br />

J, Nørgaard M, Reinholdt J, Stanchev<br />

H, [for the Danish-Swedish Multicenter<br />

Study Group for Surfactant Replacement]<br />

. Lamellar body counts on gastric<br />

aspirates for prediction of respiratory distress<br />

syndrome. Acta Paediatr<br />

<strong>2011</strong>;100(2):175-80.<br />

19. Andersen ES, Weiland O, Leutscher P,<br />

Krarup H, Westin J, Moessner B, Konopski<br />

Z, Frigstad SO, Kjær M, Christensen<br />

PB, Weis N. Low liver stiffness<br />

among cirrhotic patients with hepatitis B<br />

after prolonged treatment with nucleoside<br />

anal<strong>og</strong>s. Scand J Gastroenterol<br />

<strong>2011</strong>;46(6):760-6.<br />

20. Andersen ES, Moessner BK, Christensen<br />

PB, Kjær M, Krarup HB, Lillevang<br />

S, Weis N. Lower liver stiffness in<br />

patients with sustained virol<strong>og</strong>ical response 4<br />

years after treatment for chronic hepatitis C.<br />

Eur J Gastroenterol Hepatol<br />

<strong>2011</strong>;23(1):41-4.<br />

21. Gregersen H, Nørgaard M, Severinsen<br />

MT, Engebjerg MC, Jensen P, Sørensen<br />

HT. Monoclonal gammopathy of undetermined<br />

significance and risk of venous thromboembolism.<br />

Eur J Haematol<br />

<strong>2011</strong>;86(2):129-34.<br />

22. Omland LH, Christensen PB, Krarup<br />

HB, Jepsen P, Weis N, Sørensen HT,<br />

Obel N, [On behalf of the DANVIR<br />

Cohort Study] . Mortality among Patients<br />

with Cleared Hepatitis C Virus Infection<br />

Compared to the General Population: A<br />

Danish Nationwide Cohort Study. PLoS<br />

One <strong>2011</strong>;6(7):e22476-9.<br />

23. Tuckuviene R, Christensen A, Helgestad<br />

J, Johnsen S, Kristensen S. Paediatric<br />

arterial ischaemic stroke and cerebral sinovenous<br />

thrombosis in Denmark 1994-2006: A<br />

nationwide population-based study. Acta<br />

Paediatr <strong>2011</strong>;100(4):543-9.<br />

24. Tuckuviene R, Christensen AL, Helgestad<br />

J, Johnsen SP, Kristensen SR.<br />

Pediatric Venous and Arterial Noncerebral<br />

Thromboembolism in Denmark: A Nationwide<br />

Population-Based Study. J Pediatr<br />

<strong>2011</strong>;159(4):663-9.<br />

25. Madsen EH, Gehr NR, Johannesen NL,<br />

Schmidt EB, Kristensen SR. Platelet<br />

response to aspirin and clopid<strong>og</strong>rel in patients<br />

with peripheral atherosclerosis. Platelets<br />

<strong>2011</strong>;22(7):537-46.<br />

26. Andersen V, Christensen J, Ernst A,<br />

Jacobsen BA, Tjønneland A, Krarup<br />

HB, V<strong>og</strong>el U. Polymorphisms in NF-κB,<br />

PXR, LXR, PPARγ and risk of inflammatory

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