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Ludipress® and Ludipress LCE - Pharma Ingredients & Services BASF

Ludipress® and Ludipress LCE - Pharma Ingredients & Services BASF

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<strong>Ludipress</strong> – excellent tablets every time.<br />

<strong>Ludipress</strong> is a granulate that supports<br />

direct-compression tableting, making<br />

your life much easier. And giving you<br />

peace of mind: because you know you<br />

can be sure of great results, each <strong>and</strong><br />

every time.<br />

<strong>Ludipress</strong> yields tablets of low friability,<br />

even with low compression forces, <strong>and</strong><br />

irrespective of tableting speed.<br />

Kollidon ® CL, one of the most effective<br />

disintegrants around, means tablets<br />

start to disintegrate within moments –<br />

despite superb hardness.<br />

<strong>Ludipress</strong> yields exceptionally<br />

high-quality tablets:<br />

The following examples show how<br />

tablets based on <strong>Ludipress</strong> perform in<br />

hardness tests.<br />

200<br />

180<br />

160<br />

140<br />

120<br />

100<br />

80<br />

60<br />

40<br />

20<br />

0<br />

hardness [N]<br />

90<br />

speed [rpm]<br />

80<br />

60 40<br />

5<br />

com compression<br />

force [kN]<br />

Figure 1: The hardness of tablets produced on a state-of-the-art rotary press is not<br />

influenced by the press’s operating speed. This is illustrated by the results gained<br />

with a Glibenclamid formulation.<br />

300<br />

200<br />

100<br />

0<br />

hardness [N]<br />

<strong>Ludipress</strong><br />

Physical mixture of the<br />

individual components<br />

Excipients I <strong>Ludipress</strong> ® I PROPERTIES | 05<br />

0 10 20 30<br />

compression force [kN]<br />

Figure 2: The unique composition of <strong>Ludipress</strong> yields tablets with excellent hardness<br />

<strong>and</strong> compression properties.<br />

20<br />

15<br />

25

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