Elective theoretical subjects - Biotehniška fakulteta - Univerza v ...

and species specificities; differences in mammary gland tumor appearance in different
species; mammary gland tumor development: animal models and comparative study
approach; mammary gland as a model for proliferation and apoptosis studies; stem cells
in the mammary gland; the concept of tumor stem cells in the mammary gland; the
mammary gland as an expression system for biomedical research and production of
pharmaceutical drugs; Cell factory: human cell physiology; cell differentiation in vivo;
examples of successful clinical cell use: autologous skin substitutes, cultured autologous
cartilage and bone cells; treatment of post-infarct conditions using autologous
mesenhimal cells; isolation, characterization and differentiation of stem cells; importance
of adult human stem cells; use of bi-compatible and biodegradable materials; potential
use of new approaches in neurodegenerative disease treatment (Alzheimer's disease,
Parkinson's disease) and diabetes; in vitro gene therapy of stem cells; Host-pathogen
interactions: major signaling pathways in immune defense; mechanisms of ectopic gene
expression regulation in the thymus; immune tolerance disorders; autoimmune diseases;
complex signaling pathways in innate immunity; use of microarrays to detect the nature
of immune response and data evaluation; non-immune cells in immune response; study
of antigens and antibodies using phage display and phage libraries; strategies for
producing immune products that can be used as drugs: production of immuno-drugs
based on cytokines and antibodies;
Selected topical subjects.
4. Literature:
Scientific papers.
6. Teaching methods:
Lectures; project-seminar team work; student self-dependent problem orientated work
with teacher guidance.
7. Assessment methods:
Seminar presentation. Written examination.
8. References:
Narat Mojca
1. OVEN, Irena, BRDIČKOVÁ, Naděžda, KOHOUTEK, Jiři, VAUPOTIČ, Tomaž,
NARAT, Mojca, PETERLIN, Matija B. AIRE recruits P-TEFb for transcriptional
elongation of target genes in medullary thymic epithelial cells. Mol. cell. biol., 2007,
letn. 27, št. 24, p. 8815-8823. [COBISS.SI-ID 2213000] JCR IF (2006): 6.773, SE
(30/262), biochemistry & molecular biology, x: 3.64, SE (25/156), cell biology, x:
4.483
2. LAVRIČ, Miha, BENČINA, Dušan, KOTHLOW, Sonja, KASPERS, Bernd, NARAT,
Mojca. Mycoplasma synoviae lipoprotein MSPB, the N-terminal part of VlhA
haemagglutinin, induces secretion of nitric oxide, IL-6 and IL-ß in chicken
macrophages. Vet. microbiol.. [Print ed.], 2007, letn. 121, p. 278-287. [COBISS.SI-
ID 2003848] JCR IF (2006): 2.073, SE (50/88), microbiology, x: 3.118, SE (4/128),
veterinary sciences, x: 0.815
3. LAVRIČ, Miha, MAUGHAN, Michele N., BLISS, Travis W., DOHMS, John E.,
BENČINA, Dušan, KEELER, Calvin L., NARAT, Mojca. Gene expression
predmetation in chicken macrophages exposed to Mycoplasma synoviae or
Escherichia coli. Vet. microbiol.. [Print ed.], 2008, letn. 126, št. 1/3, p. 111-121.
[COBISS.SI-ID 2193032] JCR IF (2006): 2.073, SE (50/88), microbiology, x: 3.118,
SE (4/128), veterinary sciences, x: 0.815
Horvat Simon
1. 1. BÜNGER, Lutz, FORSTING, Jürgen, MACDONALD, Katharine, HORVAT,