22.03.2013 Views

What's New in Diabetic Neuropathy?

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Remember<br />

• This is chronic disease, and the chronic effects of drug<br />

therapies are unknown. Trials are short.<br />

• No s<strong>in</strong>gle medication has a robust effect on pa<strong>in</strong><br />

• Placebo up to 50% effective<br />

• Effectiveness poor <strong>in</strong> pa<strong>in</strong> (11%) & QOL<br />

• Side effects high<br />

• Cost is high<br />

• Pharmacologic treatment targets pa<strong>in</strong>, not numbness<br />

• Estimated numbers needed to treat (NNT) but not<br />

numbers needed to harm (NNH) available<br />

Presented by IHS Division of Diabetes<br />

36

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