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Potential Data Scope Genomic regions Genes & proteins functional summaries curated sequences, genomic context, structures orthologs, families, multiple alignments Microarray results Genotypes Protein-protein Protein protein interactions Pathway models Empirical results on hot topics Reagents antibodies, mouse models, clones, constructs, … Nat Goodman VanBUG January, 2003 Therapeutic studies drug, transplantation, gene transfer molecular, cellular, lower organism, mouse, other mammals clinical Patient information clinical & pathologic features Biomarkers Literature scanning and alerting Reports of negative and “ho- hum” results Lay explanations Slide 3
Practical Concerns Too much overlap collaborate! Nat Goodman Alzforum RefSeq GO Stanford HOPES!!! OMIM BIND ? MGD MEDLINE Too much data prioritize! Steering committee to the rescue VanBUG January, 2003 Too much software reuse! Alzforum other collaborating databases PubCrawler GBrowse BioPerl Generic Model Organism Database (GMOD) Slide 4
Page 1 and 2: Databases to Support Disease-Focuse
Page 3: What Else is Like This? Other dise
Page 7 and 8: First Data Scope for HD Website Dat
Page 9 and 10: Pathway Model (Diseased) Software:
Page 11 and 12: Steering Committee Guidelines Peer
Page 13 and 14: Compromise Community information No
Page 15 and 16: Current Core Services Genome / gen
Page 17 and 18: Help From Our Friends Mouse models
Page 19 and 20: Genome Browser Screenshot Nat Goodm
Page 21 and 22: Alzforum Papers of the Week Nat Goo
Page 23 and 24: A Few Words About IP Open source
Page 25: Acknowledgements ISB Project Team G

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