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Features<br />

22 December 2012 © Biochemical Society<br />

Science Fact and Science Fiction<br />

In Jurassic Park, a film that features molecular<br />

biology, scientists are able to a dinosaur by<br />

combining dinosaur DNA preserved inside a<br />

mosquito suspended in amber, with frogs’ eggs. As<br />

Glassy argues, in order to do this, a near complete<br />

dinosaur genome would have to be obtained. Using<br />

the techniques in the film, the scientists would<br />

have created, at best, a frog–dinosaur hybrid, not<br />

the fully hatched Tyrannosaurus that appears in<br />

the film. But the fundamental principles of genetic<br />

engineering and cloning were not fractured. The<br />

answer to the question ‘Could it happen?’ is yes,<br />

genetic engineering technology will perhaps one day<br />

advance enough that we can recreate extinct species<br />

from ancient DNA.<br />

In science-fiction classic Alien, Glassy finds “one<br />

of the most interesting life cycles in science-fiction<br />

cinema”. The film delivers credibility and kicks in a<br />

beautifully constructed documentary-style thriller.<br />

The life cycle of the alien in the film is composed<br />

of both a sexual phase and an asexual phase. The<br />

sexual phase, the mating of the alien queen, we<br />

assume happens off-screen: but the asexual phase,<br />

the hatching of the ‘facehuggers’ that begins via the<br />

victims mouth is vividly depicted. The facehugger<br />

latches on to another species and assimilates its DNA<br />

with the host. As a result of this DNA mixing, a ‘chest<br />

burster’ alien emerges from the host and grows into<br />

an adult, completing the cycle. A stunning piece of<br />

visual cinema and visionary science.<br />

The defining and thrilling idea contained within<br />

the Alien films is that the alien DNA can adapt to<br />

any species and combine them into a viable mixture<br />

capable of reproduction (a xeno-species). Since DNA<br />

is passed on from generation to generation, the alien<br />

must have previously assimilated DNA from other<br />

species, combining to make the alien the terrifying<br />

force that it has become. Somehow the alien has the<br />

ability to find the best genes it can and incorporate<br />

these into its own genome and life cycle, making it<br />

one of the most powerful and dominant species seen<br />

in science-fiction cinema.<br />

The key to the credibility of the film is that the<br />

alien life cycle depicted has examples and parallels<br />

here on Earth. It stays true to the principles of<br />

biology; it has an asexual and sexual life cycle, a<br />

cyclopropagative transmission process (much like<br />

malaria), meaning that it changes form and function<br />

as it invades and multiplies within hosts, and it<br />

survives through domination of its environment via<br />

its genes.<br />

Prometheus, the recent prequel to Alien, is, on<br />

the other hand, low on authenticity. Neither the<br />

mission, the biology nor the scientists are consistent<br />

even within the film’s own narrative world, with the<br />

filmmakers choosing instead to mix realities; the<br />

real, the fantasy and the reality within the film. Take<br />

the moment the scientists analyse the alien DNA and<br />

discover it’s a 100% match to our own. In his blog<br />

SciencePunk, Frank Swain describes how puzzling<br />

this is: “I’m not sure what this means. That we’re<br />

them, obviously. But 100%? I share 99% of my DNA<br />

with a chimp. Does that mean [the aliens] made<br />

chimps too? But if they’re a 100% match for us,<br />

where did they get the extra 1% DNA we don’t share<br />

with chimps? Do they use some other DNA that they<br />

manufactured? Does that mean the [aliens] made all<br />

life on Earth or just kick it off and let it evolve?”<br />

It is the mixing of narrative worlds in science<br />

fiction that hampers enjoyment. In Prometheus,<br />

as Frank Swain again points out, the writers make<br />

a big deal out of the characters not being able to<br />

breathe the moon’s atmosphere because of its high<br />

CO 2 potency, but the combination of gases inside<br />

the alien’s moon base enables the expedition team<br />

to breathe normally. That’s fine: the aliens modified<br />

the atmosphere inside the base to suit their lungs. So<br />

why then are the aliens wearing breathing apparatus<br />

inside their own base? And how does one alien<br />

manage to sprint unsuited out of the moon base after<br />

the scientists?<br />

For me, though, it’s the scientists that really stretch<br />

credulity far beyond breaking point. I don’t mind<br />

that they are ridiculously good-looking, younger<br />

than everyone else and are thirsty for risk – that’s<br />

believable. In fact, these qualities are an enjoyable<br />

leap away from the classic Hollywood scientist<br />

who, quoting from Christopher Frayling’s Mad, Bad<br />

and Dangerous: the Scientist and the Cinema, are<br />

almost invariably male and “are dressed in white lab<br />

coats; have frizzy hair or else none at all; they wear<br />

Coke-bottle spectacles; they work alone indoors or<br />

underground in laboratories marked ‘Secret’; they are<br />

middle-aged and not at all physically attractive”. The<br />

Prometheus scientists showed none of these clichés,<br />

which <strong>was</strong> refreshing. The notion that science might<br />

actually be interesting to people with both looks and<br />

brains is a modern idea in movie making.<br />

What <strong>was</strong>n’t so good, however, <strong>was</strong> how clueless<br />

the scientists were about everything, which, as<br />

research scientists on a trip of a lifetime, didn’t make<br />

sense. Worse, they were careless with their loot – the<br />

alien matter. Common to all working scientists I have<br />

met is the care they take over their samples: feeding,<br />

temperature, climate control, transportation, health,<br />

contamination risks and the individual needs of each<br />

precious piece of data. In this film, the scientists<br />

throw the new life forms around as if they’re custard,

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