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PUBLIC HEALTH UPDATE<br />

New Addition to the 2013 Texas Notifi able<br />

Conditions List: Chagas Disease<br />

Philip Huang, MD, MPH<br />

Medical Director/Health Authority<br />

Austin/Travis County Health and Human Services Department<br />

The Texas Department of State Health Services (DSHS)<br />

has posted the Texas Notifi able Conditions for 2013 at<br />

www.dshs.state.tx.us/idcu/investigation/conditions. Chagas<br />

disease, also referred to as American trypanosomiasis, is now a<br />

reportable condition in Texas.<br />

Chagas disease is named after the Brazilian physician,<br />

Carlos Chagas, who discovered it in 1909. Chagas is caused<br />

by the parasite trypanosome cruzi and is transmitted to<br />

animals and people by insect vectors. If infected with the<br />

T. cruzi parasite, triatomine bugs (also called reduviid bugs,<br />

“kissing” bugs, assassin bugs, cone-nosed bugs and blood<br />

suckers) can transmit the parasite during blood meal.<br />

These bugs are present in Mexico, Central America, South<br />

America and the southern United States, including Texas.<br />

DSHS Health Service Region 7 has documented the presence<br />

of the parasite T. cruzi in the triatomine bugs in our area, as<br />

noted in the following preliminary data of Table 1.<br />

Triatomine bugs can live indoors, in cracks and holes of<br />

substandard housing, but are more commonly found outdoors<br />

in a variety of settings. At this time, DSHS, in conjunction<br />

with the CDC, provides testing of triatomine bugs for the<br />

parasite T. cruzi. There currently is no charge for species<br />

identifi cation and testing; due to workload and budget<br />

constraints, testing priority is given to direct implication<br />

in a human exposure. Not all submissions will be tested.<br />

Additional resources on triatomine bug testing can found at<br />

www.dshs.state.tx.us/idcu/health/zoonosis/Triatominae.<br />

The most commonly thought of transmission mode for<br />

Chagas is vector-borne. The disease can also be acquired through<br />

blood transfusion, organ transplant and mother-to-baby<br />

(congenital transmission). Blood banks currently screen for<br />

Chagas disease. Donors are notifi ed when positive testing is<br />

found, and the blood is discarded. The disease process has an<br />

Report Chagas disease to A/TCHHSD<br />

at 512-972-5555 or by<br />

fax at 512-972-5772.<br />

For additional information on chagas disease visit:<br />

DSHS website:<br />

www.dshs.state.tx.us/idcu/disease/chagas<br />

CDC website:<br />

www.cdc.gov/parasites/chagas<br />

incubation period of one to two weeks, acute phase of eight to<br />

12 weeks, indeterminate phase can be years to decades long and<br />

chronic lifelong phase. In the acute phase, most patients are<br />

asymptomatic or mildly feverish, some display infl ammation at<br />

the site of inoculation (chagoma) or unilateral swelling of eyelids<br />

(Romana’s sign). In rare instances, patients present with severe<br />

disease such as myocarditis, pericardial effusion and<br />

meningoencephalitis. Trypomastigotes, circulating in<br />

peripheral blood, can be seen. The early chronic stage or<br />

indeterminate phase is often asymptomatic and prolonged.<br />

During this period, few to no trypomastigotes are found in the<br />

blood. Chronic disease complications include cardiomyopathy,<br />

mega-esophagus, mega-colon and neurological symptoms in<br />

immune-compromised patients. Many people remain<br />

asymptomatic for life. However, it is estimated that 20-30<br />

percent of infected people will develop debilitating and even<br />

life-threatening medical problems over the course of their lives.<br />

Diagnosis of Chagas disease during the acute phase is by<br />

microscopic examination of the parasite in a blood smear. In<br />

the chronic phase, when there are clinical fi ndings and evidence<br />

of exposure, diagnosis is generally made by testing with at least<br />

two different serological tests. Patient testing for Chagas is<br />

available through the CDC. Health care providers may call<br />

Parasitic Diseases at 404-718-4745, email chagas@cdc.gov or<br />

go to private laboratories for testing. Treatment for Chagas<br />

disease is recommended for acute infections, congenital<br />

infections, for those with suppressed immune systems and for<br />

children with chronic infections. Adults with chronic infection<br />

may benefi t from treatment as well. In the United States,<br />

medication for Chagas is available only through the CDC.<br />

Health care providers can discuss with CDC staff whether and<br />

how to treat patients diagnosed with Chagas diseases.<br />

Table 1: Triatomine bugs tested for T. cruzi parasite in Texas Health Service Region 7 Counties<br />

YEAR # TESTED # POSITIVE % COUNTIES<br />

T.cruzi POSITIVE<br />

2012 31 19 61% Blanco (1), Caldwell (6), Fayette (2), Hays (5), Travis(5)<br />

2011 18 10 56% Caldwell (7), Fayette(2), Williamson (1)<br />

2010 1 1 100% Bosque (1)<br />

Note: Individuals with possible exposure to the parasite were advised to seek a medical assessment and testing with their health care<br />

provider. Of those who sought testing, none tested positive for chagas disease.<br />

12 March • April<br />

<strong>TCMS</strong> Journal

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