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15 years of APOC - World Health Organization

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<strong>15</strong> <strong>years</strong> <strong>of</strong> <strong>APOC</strong><br />

Research<br />

<strong>APOC</strong>... in brief How <strong>APOC</strong> works<br />

<strong>APOC</strong>’s operations and activities have always been guided<br />

and based on research and evidence. Research results are used<br />

to determine all policies for control activities. <strong>APOC</strong>’s main<br />

research partner is UNDP/<strong>World</strong> Bank, WHO Special<br />

Programme for Research & Training (TDR). <strong>APOC</strong> also<br />

works with universities and other research institutions.<br />

One <strong>of</strong> the challenges facing <strong>APOC</strong> at the beginning was to<br />

determine the delivery method most capable <strong>of</strong> eliminating<br />

oncho as a public health problem? A multi-country study<br />

carried out by TDR concluded that distributors selected by<br />

the communities with support from their communities are<br />

able to carry out the distribution <strong>of</strong> Mectizan® tablets<br />

efficiently, give the correct dosage, exclude those who should<br />

not be treated and report on the distribution.<br />

Policy<br />

From Research to Policy to Implementation<br />

All research results are discussed at the Committee <strong>of</strong><br />

Sponsoring Agencies (CSA) which makes recommendations<br />

to the Joint Action Forum (JAF) for approval before<br />

implementation. In 1997 The JAF approved and adopted the<br />

Community-Directed Treatment with Ivermectin (CDTI) as<br />

the programme’s main drug delivery strategy.<br />

Implementation<br />

The <strong>APOC</strong> Strategy - CDTI<br />

The Community-Directed Treatment with Ivermectin (CDTI)<br />

adopted by <strong>APOC</strong> in 1997 relies on active participation and<br />

10<br />

promotes community ownership and empowerment <strong>of</strong><br />

communities. Communities take responsibility for ivermectin<br />

distribution and decide how, when and by whom the<br />

ivermectin treatment should be administered. CDTI has<br />

proved very successful and in the rural areas where health<br />

services are weak or sometimes even non-existent, it is<br />

contributing significantly to reducing the onchocerciasis<br />

burden in Africa. Increasingly this strategy is now being used<br />

by communities to bring other health interventions to the<br />

people who need them most.<br />

The Mectizan Donation Programme set up by Merck<br />

administers the procurement and delivery <strong>of</strong> the drugs to<br />

countries that need and request it. The MDP works closely<br />

with ministers <strong>of</strong> health and other partners<br />

Where <strong>APOC</strong> works<br />

Out <strong>of</strong> the 19 countries REMO results showed that four had<br />

mainly hypo-endemic areas with small pockets <strong>of</strong> mesoendemic<br />

communities and so would not require mass drug<br />

administration. Clinic-based treatment was therefore<br />

recommended.<br />

<strong>APOC</strong> therefore works in the remaining <strong>15</strong> countries:<br />

Angola, Burundi, Cameroon, Central African Republic, Chad,<br />

Congo, Democratic Republic <strong>of</strong> Congo, Ethiopia, Equatorial<br />

Guinea, Liberia, Malawi, Nigeria, Sudan, Tanzania, and<br />

Uganda and four ex-OCP countries: Cote d’Ivoire, Ghana,<br />

Guinea Bissau and Sierra Leone.<br />

African Programme for Onchocerciasis Control

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