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Veenstra 170 - Anxiety Disorders Association of America

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1. Overview <strong>of</strong> the Model<br />

Hierarchical Levels <strong>of</strong> Neural Processing<br />

Brain Level<br />

Higher neocortical<br />

Higher human<br />

Neocortical<br />

Human<br />

Paleocortical<br />

Mammalian<br />

Brain nuclei<br />

Reptilian<br />

Brain stem nuclei<br />

Fish<br />

Spinal & body nerves<br />

Body<br />

Main function<br />

Mindful examination <strong>of</strong><br />

lower levels <strong>of</strong> experiencing<br />

Verbal thinking about how to<br />

respond to life situation<br />

Emotional responding to life<br />

situations and others<br />

Instinctive adjustment <strong>of</strong> life<br />

processes for survival needs<br />

Automatic regulation <strong>of</strong> life<br />

processes to maintain homeostatis<br />

Living existence<br />

Location <strong>of</strong> Nuclei within the Brain<br />

Midbrain view <strong>of</strong> right hemisphere<br />

looking up from front underside<br />

Hypothalamus<br />

Thalamus<br />

Amygdala<br />

(Inside temporal lobe)<br />

PAG<br />

periaqueductal<br />

gray nuclei<br />

Amygdala Regulation Problem<br />

Amygdala is only<br />

danger detector<br />

Turns "on"<br />

not "<strong>of</strong>f"<br />

Learns to fear<br />

sign <strong>of</strong><br />

physiological<br />

arousal<br />

Rapid<br />

heart rate<br />

When detects arousal,<br />

it responds by<br />

Positive<br />

feedback<br />

system<br />

Sympathetic<br />

autonomic arousal<br />

Paleocortical Anatomy<br />

If no higher safety signal available<br />

Tries to escape,<br />

but cannot<br />

Increasing<br />

autonomic<br />

arousal<br />

Intensity<br />

increases<br />

Input <strong>of</strong><br />

data<br />

Limbic Nuclei<br />

Stria<br />

terminalis<br />

Corpus<br />

callosum<br />

Septal<br />

nuclei<br />

Olfactory<br />

bulb<br />

Anterior<br />

commisure<br />

Neocortical<br />

Thinking<br />

Paleocortical<br />

Emoting<br />

Brain Nuclei<br />

Reacting<br />

Decision<br />

making<br />

Amygdala<br />

Fornix<br />

Neocortical Anatomy<br />

PreFrontal Cortex<br />

<strong>Association</strong><br />

Area<br />

Human<br />

Mammalian<br />

Reptilian<br />

Output<br />

actions<br />

Mammilliary<br />

nucleus<br />

Hippocampus<br />

Neocortex is mainly two large multimodal association areas<br />

Parietal-<br />

Occipital-<br />

Temporal<br />

<strong>Association</strong><br />

Area<br />

Human neocortex is 3 times larger than chimpanzee<br />

© Glenn <strong>Veenstra</strong> 3/13

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