Analytica Chimica Acta Volume 751, Pages 1-188 (2 November 2012)
Analytica Chimica Acta Volume 751, Pages 1-188 (2 November 2012)
Analytica Chimica Acta Volume 751, Pages 1-188 (2 November 2012)
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Highlights<br />
► Visual detection based gold and silver nanoparticles aggregation. ► Functionalized and nonfunctionalized<br />
nanoparticles. ► High selectivity and sensitivity. ► No complex instrumentation is<br />
required/chemical creativity for analyte detection.<br />
Chemometrics<br />
Validation of analytical methods involved in dissolution assays:<br />
Acceptance limits and decision methodologies<br />
Original Research Article<br />
<strong>Pages</strong> 44-51<br />
E. Rozet, E. Ziemons, R.D. Marini, B. Boulanger, Ph. Hubert<br />
Graphical abstract<br />
Highlights<br />
► Novel methodology to validate analytical methods involved in dissolution tests. ► Valid methods<br />
will ensure to make the correct decisions with high probability. ► A Quality by Design compliant<br />
validation methodology for dissolution assays. ► <strong>Analytica</strong>l Target Profile is defined for dissolution<br />
assays. ► Application to the validation of a HPLC–UV analytical method.<br />
Electrochemistry<br />
Nanoplatinum-enclosed gold nanocores as catalytically promoted<br />
nanolabels for sensitive electrochemical immunoassay