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Aircrew and Spacecrew Radiation Exposure - media.cns-snc.ca

Aircrew and Spacecrew Radiation Exposure - media.cns-snc.ca

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Biologi<strong>ca</strong>l Effects of Ionizing <strong>Radiation</strong><br />

• Ionizing radiation <strong>ca</strong>uses atoms <strong>and</strong> molecules to become ionized or excited:<br />

– Produce free radi<strong>ca</strong>ls<br />

– Break chemi<strong>ca</strong>l bonds<br />

– Produce new chemi<strong>ca</strong>l bonds <strong>and</strong> cross-linkage between macromolecules<br />

– Damage molecules that regulate vital cell processes (e.g. DNA, RNA, proteins).<br />

• Tissues that undergo rapid cell regeneration are most<br />

sensitive to radiation (e.g., blood-forming organs,<br />

reproductive organs, <strong>and</strong> lymphatic system)

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