Buprenorphine Cost Effectiveness
Buprenorphine Cost Effectiveness
Buprenorphine Cost Effectiveness
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Data from Published Cohort Study<br />
• Patients had been followed in an RCT of buprenorphine<br />
management strategies and successfully completed 24 weeks on<br />
buprenorphine/naloxone (w/ at least 9 weeks abstinence) 1<br />
• We used follow-up study data on retention in treatment up to 24<br />
months after completion of the RCT 2<br />
• For those not retained in treatment, assumed 89% to be actively<br />
using drugs when out of treatment 3<br />
• Unit cost data from previous analysis of the same cohort 4<br />
• Average weekly cost for IDU and non-IDUs calculated based on<br />
patient-level resource utilization<br />
• For sensitivity analysis on drug cost, examined generic cost 80% of<br />
branded cost<br />
1 Fiellin et. al, N Engl J Med, 2006<br />
2 Fiellin et. al, Am J Addict., 2006<br />
3 Connock et al. Health Technology Assessment, 2006<br />
4 Jones et. al, Drug Alcohol Depend., 2009<br />
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