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Imaging Non-Hodgkin's Lymphoma - Lieberman's eRadiology ...

Imaging Non-Hodgkin's Lymphoma - Lieberman's eRadiology ...

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Guibenson Hyppolite, HMS III<br />

Gillian Lieberman, MD<br />

Hodgkin’s<br />

Reed-Sternberg Reed Sternberg cells<br />

90% originate in lymph<br />

node<br />

95% superior mediastinal<br />

nodal<br />

Contiguous progression<br />

Incidence: 1:50,000<br />

Bimodal age distribution:<br />

30 & 70<br />

<strong>Lymphoma</strong><br />

September 2004<br />

<strong>Non</strong>-Hodgkin’s<br />

<strong>Non</strong> Hodgkin’s<br />

Heterogeneous group<br />

60% originate in lymph<br />

nodes<br />

85% from B cells; 15%<br />

from T cells<br />

Occurs in all age groups<br />

(mean age 50 years)<br />

Increased incidence in<br />

patients with altered<br />

immune status<br />

13

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