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12 th<br />

European<br />

Stroke<br />

Conference<br />

Valencia, Spain May 21 – 24, 2003<br />

www.<strong>eu</strong>rostroke.org<br />

<strong>FINAL</strong> <strong>PROGRAMME</strong>


Acknowledgements<br />

ESC expresses its thanks and appreciation to those companies and organisations which are<br />

generously contributing to the success of the 12 th European Stroke Conference:<br />

Sanofi-Synthelabo / Bristol-Myers Squibb<br />

Boehringer Ingelheim<br />

NMT Medical<br />

Ferrer Group<br />

Bayer Health Care<br />

Grupo Uriach<br />

Pfizer<br />

Cochrane Stroke Group /<br />

Stroke Unit Trialists Collaboration /<br />

European Stroke Unit Group<br />

Novo Nordisk<br />

MSD<br />

Cerebricon<br />

Bioscience Ediprint<br />

DWL Elektronische Systeme<br />

Wisepress Bookshop<br />

S. Karger


Contents<br />

Welcome Address . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2<br />

Committees . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3/4<br />

Important Addresses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5<br />

Scientific Programme at a Glance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6–9<br />

Scientific Programme<br />

– Wednesday, May 21, 2003 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10–14<br />

– Thursday, May 22, 2003 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15–26<br />

– Friday, May 23, 2003 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27–45<br />

– Saturday, May 24, 2003 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46–53<br />

Poster Sessions<br />

– Thursday, May 22, 2003 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54–78<br />

– Friday, May 23, 2002 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79–105<br />

Instructions for Authors<br />

– Oral Presentations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 106<br />

– Poster Presentations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 107<br />

Welcome Reception . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 108<br />

Accompanying Persons Programme . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 109<br />

General Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 110–116<br />

Conference Venue Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 118<br />

List of Exhibitors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 119<br />

Exhibition and Conference Venue Plan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 120/121<br />

Valencia Sights . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 122/123<br />

13 th European Stroke Conference ESC 2004<br />

May 12 – 15, 2004<br />

Mannheim / Heidelberg, Germany<br />

1


Welcome Address<br />

Dear Colleagues and Friends,<br />

It is certainly an honour and a great privilege to welcome you to Valencia to attend the<br />

12th European Stroke Conference.<br />

The European Stroke Conference is one of the most important n<strong>eu</strong>rological meetings in<br />

Europe, and with its specific dedication to cerebrovascular diseases it has managed to<br />

attract a huge attendance. Participants are not only clinicians but also some other multiple<br />

research and health care professionals who deal with the multifaceted aspects of the<br />

stroke. The conference programme includes special lectures, symposia, teaching courses,<br />

platform and poster presentations. It is our intention to keep alive the spirit of lively<br />

discussions, which forms part of the most intimate soul of these meetings.<br />

We hope this conference will allow us to improve our skills in stroke care and will help us<br />

to offer a better future for our stroke patients.<br />

We are sure that the warm and kind environment, which you find in the ancient<br />

Mediterranean city of Valencia formed by the successive admixture of many different<br />

cultures devoted to trade, will help you to enjoy your stay with us. Just a few<br />

recommendations: Do not miss its old neighbourhoods, its ancient university, where Cajal<br />

worked for some years at the beginning of his career, its nice gastronomy in which rice<br />

is king, or the new buildings at Ciutat de les Arts i les Ciències due to Santiago Calatrava.<br />

Make yourself at home in Valencia and enjoy the conference.<br />

Jordi Matías-Guiu<br />

Chairman of the Local Organising Committee<br />

2


Committees<br />

Programme Committee<br />

Chairman:<br />

Michael G. Hennerici, Germany<br />

Julien Bogousslavsky, Switzerland<br />

Martin Brown, United Kingdom<br />

José M. Ferro, Portugal<br />

Gian Luigi Lenzi, Italy<br />

Jean-Louis Mas, France<br />

Jorge Matías-Guiu, Spain<br />

Bo Norrving, Sweden<br />

Nils-Gunnar Wahlgren, Sweden<br />

Scientific Committee<br />

Chairman:<br />

J. Bogousslavsky, Switzerland<br />

F. Aichner, Austria<br />

P. Amarenco, France<br />

N.D. Artemis, Greece<br />

R. Baumgartner, Switzerland<br />

S. Blecic, Belgium<br />

N. Bornstein, Israel<br />

M. Brown, United Kingdom<br />

A. Carolei, Italy<br />

L. Csiba, Hungary<br />

A. Czlonkowska, Poland<br />

M. Daffertshofer, Germany<br />

A. Davalos, Spain<br />

S. Davis, Australia<br />

J. De R<strong>eu</strong>ck, Belgium<br />

E. Diez Tejedor, Spain<br />

F. Fazekas, Austria<br />

J.M. Ferro, Portugal<br />

W. Hacke, Germany<br />

G. Hankey, Australia<br />

M.G. Hennerici, Germany<br />

I. Henriques, Portugal<br />

D. Inzitari, Italy<br />

D. Karacostas, Greece<br />

M. Kaste, Finland<br />

P. Koudstaal, The Netherlands<br />

E. Kumral, Turkey<br />

W. Kuschinsky, Germany<br />

G.L. Lenzi, Italy<br />

D. Leys, France<br />

J. Lodder, The Netherlands<br />

H. Markus, United Kingdom<br />

J.L. Marti-Vilalta, Spain<br />

J.L. Mas, France<br />

J. Matías-Guiu, Spain<br />

H. Mattle, Switzerland<br />

J.P. Mohr, USA<br />

B. Norrving, Sweden<br />

J.M. Orgogozo, France<br />

K. Overgaard, Denmark<br />

G. Oezdemir, Turkey<br />

P.M. Rothwell, United Kingdom<br />

D. Russell, Norway<br />

P. Sandercock, United Kingdom<br />

D. Toni, Italy<br />

R. von Kummer, Germany<br />

N.G. Wahlgren, Sweden<br />

S. Warach, USA<br />

C. Warlow, United Kingdom<br />

3


Committees<br />

Local Organising Committee<br />

Chairman:<br />

Jorge Matías-Guiu, Alicante<br />

Co-Chairman:<br />

Exuperio Diez Tejedor, Madrid<br />

Francisco Gracia, Alicante (Secretariat)<br />

José Manuel Moltó, Alicante (Secretariat)<br />

Angel Pérez, Alicante (Secretariat)<br />

José Alvarez-Sabín, Barcelona<br />

José Antonio Egido, Madrid<br />

4<br />

Alberto Gil-Peralta, Sevilla<br />

Aida Lago, Valencia<br />

José Miguel Láinez, Valencia<br />

José Larracoechea, Bilbao<br />

Eduardo Martínez-Vila, Pamplona<br />

Ricardo Navarro, Oviedo<br />

Francisco Rubio, Barcelona<br />

José Villanueva, Madrid<br />

José Vivancos, Madrid


Important Addresses<br />

Congress Palacio de Congresos Phone +34 96 317 94 34<br />

Venue Avda. Cortes Valencianas, 60 Fax +34 96 317 94 35<br />

E-46015 Valencia, Spain<br />

Scientific Prof. Dr. Julien Bogousslavsky Phone +41 21 314 12 30<br />

Committee Département de N<strong>eu</strong>rologie Fax +41 21 314 12 31<br />

Centre Hospitalier Universitaire E-mail julien.bogousslavsky@<br />

Vaudois CHUV<br />

CH-1011 Lausanne, Switzerland<br />

chuv.hospvd.ch<br />

Programme Prof. Dr. Michael G. Hennerici Phone +49 621 383 28 85<br />

Committee N<strong>eu</strong>rologische Universitätsklinik Fax +49 621 383 38 07<br />

Universität Heidelberg E-mail hennerici@n<strong>eu</strong>ro.ma.<br />

D-68135 Mannheim, Germany<br />

uni-heidelberg.de<br />

Administrative ESC 2003 Phone +41 61 686 77 11<br />

Secretariat c/o AKM Congress Service Fax +41 61 686 77 88<br />

PO Box E-mail info@akm.ch<br />

CH-4005 Basel, Switzerland<br />

Exhibition AKM Congress Service Phone +41 61 686 77 66<br />

Exhibition Department Fax +41 61 686 77 88<br />

PO Box E-mail exhibition@akm.ch<br />

CH-4005 Basel, Switzerland<br />

Hotel AKM Travel Phone +41 61 690 94 11<br />

Accommodation Messeplatz 10 Fax +41 61 690 94 14<br />

and Tours PO Box E-mail akmtravel@akm.ch<br />

CH-4016 Basel, Switzerland<br />

www.<strong>eu</strong>rostroke.org<br />

5


Programme at a Glance Wednesday, May 21, 2003<br />

07.00<br />

07.30<br />

08.00<br />

08.30<br />

09.00<br />

09.30<br />

10.00<br />

10.30<br />

11.00<br />

11.30<br />

12.00<br />

12.30<br />

13.00<br />

13.30<br />

14.00<br />

14.30<br />

15.00<br />

15.30<br />

16.00<br />

16.30<br />

17.00<br />

17.30<br />

18.00<br />

18.30<br />

19.00<br />

19.30<br />

6<br />

Auditorium I Auditorium II Committee Rooms<br />

Satellite Symposium<br />

Sanofi-Synthelabo/BMS<br />

Satellite Symposium<br />

Pfizer<br />

Teaching Courses


Thursday, May 22, 2003<br />

Auditorium I Auditorium II Auditorium III<br />

Educational Symposium I<br />

Sanofi-Synthelabo/BMS<br />

Educational Symposium II<br />

NMT Medical<br />

Coffee Break<br />

Stroke in the World Risk Factors of Stroke<br />

Satellite Symposium<br />

Iberoamerican<br />

Cerebrovascular<br />

Disease Society<br />

Lunch and Poster Preview I<br />

Poster Session I<br />

Satellite Symposium<br />

Boehringer Ingelheim<br />

Genetics and Molecular<br />

Markers in Stroke<br />

Dementia and Cognitive<br />

Dysfunction<br />

Satellite Symposium<br />

Grupo Uriach<br />

07.00<br />

07.30<br />

08.00<br />

08.30<br />

09.00<br />

09.30<br />

10.00<br />

10.30<br />

11.00<br />

11.30<br />

12.00<br />

12.30<br />

13.00<br />

13.30<br />

14.00<br />

14.30<br />

15.00<br />

15.30<br />

16.00<br />

16.30<br />

17.00<br />

17.30<br />

18.00<br />

18.30<br />

19.00<br />

19.30<br />

7


Programme at a Glance Friday, May 23, 2003<br />

07.00<br />

07.30<br />

08.00<br />

08.30<br />

09.00<br />

09.30<br />

10.00<br />

10.30<br />

11.00<br />

11.30<br />

12.00<br />

12.30<br />

13.00<br />

13.30<br />

14.00<br />

14.30<br />

15.00<br />

15.30<br />

16.00<br />

16.30<br />

17.00<br />

17.30<br />

18.00<br />

18.30<br />

19.00<br />

19.30<br />

8<br />

Auditorium I Auditorium II Auditorium III<br />

Stroke Unit Concepts – Stroke<br />

Monitoring<br />

Acute Stroke<br />

Symptoms and Diagnosis<br />

Acute Stroke<br />

Treatment Concepts<br />

Acute Stroke<br />

Outcome<br />

Introduction Introduction<br />

Diagnosis and Treatment with<br />

Ultrasound<br />

Coffee Break<br />

Venous Diseases<br />

Meta-Analyses and Reviews<br />

Lunch and Poster Preview II<br />

Recovery and<br />

Rehabilitation<br />

Poster Session II<br />

Satellite Symposium<br />

EUSI<br />

Vascular, Interventional<br />

and N<strong>eu</strong>rosurgery<br />

Experimental<br />

Studies<br />

Cardiovascular Topics:<br />

PFO and IMT<br />

Satellite Symposium*<br />

* Cochrane Stroke Group/Stroke Unit Trialists Collaboration/European Stroke Unit Group


Saturday, May 24, 2003<br />

Auditorium I Auditorium II Auditorium III<br />

ICH and SAH<br />

Invited Lecture<br />

Award Presentations<br />

News from Large<br />

Clinical Trials<br />

Closure and Announcement of ESC 2004<br />

N<strong>eu</strong>roimaging Management and Economics<br />

Coffee Break<br />

07.00<br />

07.30<br />

08.00<br />

08.30<br />

09.00<br />

09.30<br />

10.00<br />

10.30<br />

11.00<br />

11.30<br />

12.00<br />

12.30<br />

13.00<br />

13.30<br />

14.00<br />

14.30<br />

15.00<br />

15.30<br />

16.00<br />

16.30<br />

17.00<br />

17.30<br />

18.00<br />

18.30<br />

19.00<br />

19.30<br />

9


Scientific Programme Wednesday, May 21, 2003<br />

14.00–17.00 Committee Rooms<br />

10<br />

Teaching Course 1: Genetics in Stroke<br />

Chair: H. Markus, United Kingdom<br />

Genetics of monogenic ischaemic stroke including CADASIL<br />

M. Dichgans, Germany<br />

Genetics of polygenic stroke including study design<br />

H. Markus, United Kingdom<br />

The use of intermediate phenotypes in genetic research<br />

R. Schmidt, Austria<br />

Monogenic disorders causing intracranial haemorrhage<br />

J. Haan, The Netherlands<br />

Teaching Course 2: Less Common Causes of Stroke<br />

Chair: S. Blecic, Belgium<br />

Update on dissections<br />

T. Brandt, Germany<br />

Acute vasculitis<br />

S. Blecic, Belgium<br />

Mitochondrial disorders and stroke<br />

A.L. Andr<strong>eu</strong>, Spain<br />

Cerebral amyloid angiopathy and stroke: clinical spectrum<br />

D. Leys, France


Teaching Course 3: Rehabilitation and Recovery<br />

Chair: C. Weiller, Germany<br />

Endogenous and exogenous cell therapy in stroke<br />

J. Winkler, Germany<br />

Imaging issues in stroke recovery<br />

C. Weiller, Germany<br />

CI therapy and affiliates<br />

C. Dettmers, Germany<br />

Early supported discharge – the future of stroke rehabilitation<br />

P. Langhorne, United Kingdom<br />

Teaching Course 4: Specific Diagnostics<br />

Chair: H. Mattle, Switzerland<br />

Ultrasound standard/experienced (2 groups)<br />

H. Mattle, Switzerland and M. Daffertshofer, Germany<br />

Infarct, haemorrhage, tumour or what?<br />

Basics in CT and MRI interpretation. CT/MRI experienced (2 groups)<br />

R. von Kummer, Germany and J. Röther, Germany<br />

Cardiac procedures<br />

C. Seiler, Switzerland<br />

N<strong>eu</strong>ropsychology<br />

J. Ferro, Portugal<br />

11


Scientific Programme Wednesday, May 21, 2003<br />

14.00–17.00 Committee Rooms<br />

12<br />

Teaching Course 5: Multidisciplinary Caring Issues after<br />

Stroke<br />

Chair: M. Walker, United Kingdom<br />

Secondary complications after stroke<br />

B. Indredavik, Norway<br />

Cognitive, emotional and behavioural consequences<br />

of stroke<br />

J. Hochstenbach, The Netherlands<br />

Non-pharmacological approach to depression<br />

N. Lincoln, United Kingdom<br />

Care in the community<br />

M. Walker, United Kingdom


17.00–18.30 Auditorium I<br />

Satellite Symposium sponsored by Sanofi-Synthelabo/BMS:<br />

Exploring New Antiplatelet Strategies in Stroke Prevention<br />

Chairs: W. Hacke, Germany and A. Davalos, Spain<br />

17.00–17.05 Introduction<br />

W. Hacke, Germany and A. Davalos, Spain<br />

17.05–17.25 Role of inflammation in stroke and atherothrombosis<br />

A. Chamorro, Spain<br />

17.25–17.45 Recent clinical trial results with antiplatelet therapy:<br />

implications in stroke prevention<br />

P. Teal, Canada<br />

17.45–18.05 Atrial fibrillation: exploring a new role for antiplatelet<br />

therapy?<br />

S. Connolly, Canada<br />

18.05–18.25 Ongoing trials with antiplatelet therapy in acute and<br />

secondary stroke prevention – setting a new standard<br />

of care?<br />

G. Hankey, Australia<br />

18.25–18.30 Conclusion<br />

W. Hacke, Germany and A. Davalos, Spain<br />

13


Scientific Programme Wednesday, May 21, 2003<br />

17.00–18.30 Auditorium II<br />

14<br />

Satellite Symposium sponsored by Pfizer:<br />

Stroke Prevention and Potential Role of Statins<br />

Chair: J. Bogousslavsky, Switzerland<br />

16.30–17.00 Refreshments<br />

17.00–17.05 Welcome and introduction<br />

J. Bogousslavsky, Switzerland<br />

17.05–17.25 Stroke prevention and lipid lowering: an evolving relationship<br />

M.G. Hennerici, Germany<br />

17.25–17.45 The biological basis for statin therapy in stroke prevention –<br />

anti-atherosclerotic properties<br />

H. Sillesen, Denmark<br />

17.45–18.05 The biological basis for statin therapy in stroke prevention –<br />

n<strong>eu</strong>roprotective properties beyond lipid lowering<br />

R. Paoletti, Italy<br />

18.05–18.25 The Anglo-Scandinavian Cardiac Outcomes Trial ASCOT:<br />

impact of statin therapy on stroke in a hypertensive population<br />

B. Dahlöf, Sweden<br />

18.25–18.30 Summary and close<br />

J. Bogousslavsky, Switzerland


Thursday, May 22, 2003<br />

08.30–10.30 Auditorium I<br />

Educational Symposium sponsored by Sanofi-Synthelabo/BMS:<br />

Imaging: Upcoming Techniques and Implications for<br />

Treatment<br />

Chairs: J. Bogousslavsky, Switzerland and E. Diez Tejedor, Spain<br />

08.30–08.35 Introduction<br />

J. Bogousslavsky, Switzerland and E. Diez Tejedor, Spain<br />

08.35–09.00 The unstable plaque<br />

M.G. Hennerici, Germany<br />

09.00–09.25 Advances in penumbra imaging with MR<br />

S. Davis, Australia<br />

09.25–09.50 Imaging viable brain tissue with CT scan<br />

R. M<strong>eu</strong>li, Switzerland<br />

09.50–10.15 Towards a new mapping of brain cortex function<br />

R. Frackowiak, United Kingdom<br />

10.15–10.30 Conclusion<br />

J. Bogousslavsky, Switzerland and E. Diez Tejedor, Spain<br />

10.30–11.00 Coffee Break<br />

15


Scientific Programme Thursday, May 22, 2003<br />

11.00–13.00 Auditorium I<br />

16<br />

Oral Session: Stroke in the World<br />

Chairs: J. Matias-Guiu, Spain and G. Hankey, Australia<br />

11.00–11.10 First-ever stroke incidence and stroke sub-type in a predominantly<br />

black population, Barbados, West Indies<br />

D.O.C. Corbin, V. Poddar, A. Hennis, H. Fraser, C. Wolfe, R. Wilks,<br />

Chronic Disease Research Centre, School of Clinical Medicine and Research,<br />

UWI, Barbados<br />

11.10–11.20 Stroke epidemiology in Russia<br />

E.I. Gusev, V.I.Skvortsova, L.V. Stakhovskaya, N.Y. Airian,<br />

Russian State Medical University, Russian Federation<br />

11.20–11.30 First year results of the Third Stroke Registry in Tartu, Estonia<br />

R. Vibo, J. Kõrv, M. Roose, University of Tartu, Estonia<br />

11.30–11.40 Implications of rates of non-fatal acute cerebrovascular versus<br />

coronary vascular events for provision of acute services:<br />

Oxford Vascular Study<br />

C. Coull, L. Silver, P. Rothwell, Stroke Prevention Research Unit,<br />

University of Oxford, United Kingdom<br />

11.40–11.50 A 5-year prospective study of young stroke in China<br />

M. Weiwei Zhang, Z. Zhang, Q. Bi, Y. Wang, W. Ma, China<br />

11.50–12.00 Comparison of worldwide First-ever-in-a-lifetime (FES) stroke<br />

incidence risk: implications for current and future stroke incidence<br />

P. Syme, A. Byrne, R. Chen, A. Finlayson, Borders General Hospital,<br />

University of Edinburgh, United Kingdom<br />

12.00–12.10 The Tintswalo Hospital Stroke Register:<br />

a rural South African stroke register<br />

M. Connor, B. Casserly, M. Thorogood, C. Warlow, SASPI Project Team,<br />

University of the Witwatersrand, South Africa


12.10–12.20 The community-based incidence of stroke in a Scottish population,<br />

the Scottish Borders Stroke Study (SBSS)<br />

P. Syme, A. Byrne, R. Devenny, R. Chen, J. Forbes,<br />

University of Edinburgh, United Kingdom<br />

12.20–12.30 Eligibility for acute stroke therapy in the community:<br />

estimates from North East Melbourne Stroke Incidence Study<br />

(NEMESIS), an Australian population based stroke incidence study<br />

A.K. Gilligan, J.W. Sturm, H.M. Dewey, G.A. Donnan, R.A. Macdonell,<br />

A.G. Thrift, National Stroke Research Institute, Australia<br />

12.30–12.40 LiLAC – Life Long After Cerebral ischemia. Preliminary results on<br />

long-term (>10 years) survival in patients with cerebral ischaemia of<br />

arterial origin<br />

I. van Wijk, A. Algra, LiLAC Study Group, University Medical Centre Utrecht,<br />

The Netherlands<br />

12.40–12.50 The Third Auckland Regional Community Stroke Study: early results<br />

M.L. Hackett, C.S. Anderson, K. Carter, V. Feigin, N. Anderson, A. Barber,<br />

P. Brown, N. Kerse, R. Bonita, ARCOS Collaborative Group,<br />

Clinical Trials Research Unit, Faculty of Medicine and Health Science,<br />

New Zealand<br />

12.50–13.00 Accurate early diagnosis with and without n<strong>eu</strong>roimaging studies<br />

C. Marini, T. Russo, I. Ciancarelli, D. Cerone, M. Baldassarre, A. Carolei,<br />

University of L'Aquila, Italy<br />

17


Scientific Programme Thursday, May 22, 2003<br />

11.00–13.00 Auditorium II<br />

18<br />

Oral Session: Risk Factors of Stroke<br />

Chairs: J.M. Orgogozo, France and P. Sandercock, United Kingdom<br />

11.00–11.10 Predictive value of the combined measurement of IMT, ABI and hsCRP<br />

for the development of new cerebrovascular events:<br />

results of the prospective population-based INVADE trial<br />

D. Sander, U. Scherpinski, H. Bickel, H. Gnahn, B. Conrad,<br />

Technical University of Munich, Germany<br />

11.10–11.20 Risk factors and prognosis of lacunar stroke in a population study<br />

S. Sacco, C. Marini, F. De Santis, M. Baldassarre, L. Olivieri, A. Carolei,<br />

University of L'Aquila, Italy<br />

11.20–11.30 Fasting plasma glucose and risk of incident ischemic stroke and<br />

transient ischemic attacks: A J Shaped Association<br />

D. Tanne, N. Koren-Morag, U. Goldbourt, Sheba Medical Center, Israel<br />

11.30–11.40 C reactive protein predicts further major vascular events in stroke<br />

patients with intracranial atherosclerotic stenoses<br />

J.F. Arenillas, C.A. Molina, P. Chacon, J. Montaner, A. Rovira, A. Penalba,<br />

M. Quintana, J. Alvarez-Sabín, Cerebrovascular Unit, Vall d'Hebron Hospital,<br />

Spain<br />

11.40–11.50 Increased l<strong>eu</strong>kocyte-platelet complex formation in acute<br />

symptomatic compared with asymptomatic severe carotid stenosis<br />

D.J.H. McCabe, P. Harrison, I.J. Mackie, P.S. Sidhu, G. Purdy, A.S. Lawrie,<br />

H. Watt, S.J. Machin, M.M. Brown, Stroke Research Unit, Institute of<br />

N<strong>eu</strong>rology, The National Hospital for N<strong>eu</strong>rology & N<strong>eu</strong>rosurgery and<br />

The Haemostasis Research Unit, Department of Haematology,<br />

University College London, United Kingdom<br />

11.50–12.00 Is the association between self-reported stress and stroke modified<br />

by alcohol?<br />

N. Nielsen, J. Barefoot, T. Truelsen, S. Paaske, K. Overvad, P. Schnohr,<br />

M.M. Grønbæk, Alcohol Research, National Institute of Public Health, Denmark


12.00–12.10 Cerebral microbleeds is a risk factor for subsequent intracerebral<br />

hemorrhage among patients with acute ischemic stroke<br />

Y.H. Fan, L. Zhang, V. Mok, W.W. Lam, K.S. Wong, Chinese University of<br />

Hong Kong, Hong Kong<br />

12.10–12.20 Prevalence of aspirin resistance in a population-based study of<br />

patients with acute vascular events: Oxford Vascular Study (OXVASC)<br />

L. Silver, A. Coull, P. Harrison, H. Segal, P. Rothwell,<br />

Stroke Prevention Research Unit, University of Oxford, United Kingdom<br />

12.20–12.30 Protein Z in ischaemic stroke and its aetiological subtypes<br />

G. Hankey, A. McQuillan, J. Eikelboom, R. Baker, J. Thom, J. Staton, Q. Yi,<br />

V. Cole, Royal Perth Hospital, Australia<br />

12.30–12.40 Peripheral arterial disease in Asian stroke patients: frequency,<br />

risk factors and association with stroke sub-type<br />

R. Esagunde, C.F. Chan, H.B. Pey, H.H. Tey, A. Auchus, H.M. Chang,<br />

M.C. Wong, C. Chen, National N<strong>eu</strong>roscience Institute,<br />

Singapore General Hospital Campus, Singapore<br />

12.40–12.50 Brain arteriovenous malformations: age-dependent clinical and<br />

morphologic characteristics in a prospective patient cohort<br />

C. Stapf, A.V. Khaw, H.C. Schumacher, R.R. Sciacca, A. Hartmann, H. Mast,<br />

J.P. Mohr, Columbia University College of Physicians & Surgeons, USA<br />

12.50–13.00 Ischemic tolerance biochemical factor in transitory ischemic attack<br />

patients<br />

M. Blanco, R. Leira, I. Lizasoain, M.A. Moro, A. Davalos, J. Castillo,<br />

Hospital Clínico Universitario de Santiago de Compostela, Spain<br />

19


Scientific Programme Thursday, May 22, 2003<br />

11.00–12.00 Auditorium III<br />

20<br />

Oral Session: Genetics and Molecular Markers in Stroke<br />

Chairs: M. Dichgans, Germany and H. Markus, United Kingdom<br />

11.00–11.10 Angiotensin converting enzyme: the DD genotype is associated with<br />

carotid artery stenosis in non-diabetic men<br />

U. Schminke, J. Luedemann, A. Kilian, F. Herrmann, U. John, C. Kessler,<br />

Ernst-Moritz-Arndt University, Germany<br />

11.10–11.20 TNF-alpha G-308A gene polymorphism and the clinical course<br />

of cerebral infarction<br />

G. Gromadzka, M. Baranska, A. Ciesielska, T. Mendel, I. Sarzynska-Dlugosz,<br />

A. Czlonkowska, Institute of Psychiatry and N<strong>eu</strong>rology, Poland<br />

11.20–11.30 Pro-inflammatory gene-load is associated with enhanced<br />

inflammation and early carotid artery atherosclerosis in smokers<br />

P. Jerrard-Dunne, M. Sitzer, P. Risley, A. Buehler, S. von Kegler, H.S. Markus,<br />

St. George’s Hospital Medical School, United Kingdom<br />

11.30–11.40 Polymorphisms of the angiotensin converting enzyme,<br />

angiotensinogen and endothelial nitric oxide synthase genes in the<br />

carotid atherothrombotic stroke<br />

S.A. Limborska, E.A. Roltsova, P.A. Slominsky, I.M. Shetova, T.I. Tupitsina,<br />

V.I. Skvortsova, Russian State Medical University, Institute of Molecular<br />

Genetics, Russian Federation<br />

11.40–11.50 Headache in intracerebral hemorrhages is associated with molecular<br />

markers for inflammation and predicts the volume of the residual lesion<br />

R. Leira, Y. Silva, J. Tejada, A. Gil, E. Mostacero, J. Castillo, Proyecto Ictus del<br />

GEECV de la SEN, Spain<br />

11.50–12.00 Evidence of publication bias in genetic epidemiology:<br />

a systematic review<br />

E. Flossmann, U.G. Schulz, P.M. Rothwell, Stroke Prevention Research Unit,<br />

Radcliffe Infirmary, University of Oxford, United Kingdom


12.00–13.00 Auditorium III<br />

Oral Session: Dementia / Higher Cognitive Dysfunction<br />

Chairs: G.L. Lenzi, Italy and D. Leys, France<br />

12.00–12.10 Predicting dementia in patients with cerebrovascular disease:<br />

results from PROGRESS<br />

Y. Ratnasabapathy, C.A. Anderson, C. Tzourio, M. Jones, PROGRESS<br />

(Perindopril Protection against Recurrent Stroke Study) Collaborative Group,<br />

Clinical Trials Research Unit, University of Auckland and Institute of<br />

International Health, University of Sydney, New Zealand and Australia<br />

12.10–12.20 Long-term n<strong>eu</strong>ropsychological dysfunction in young adults with<br />

stroke. A case-control study<br />

C. Jacas, N. Lopez, R. Galisteo, M. Ribo, J.F. Arenillas, C. Molina, M. Vilardell,<br />

J. Alvarez-Sabín, Vall d'Hebron General Hospital, Spain<br />

12.20–12.30 Age-related white matter changes as a predictor of disability in the<br />

elderly: the LADIS (L<strong>eu</strong>koaraiosis and disability) project<br />

D. Inzitari, LADIS Study Group, Department of N<strong>eu</strong>rological and Psychiatric<br />

Sciences, University of Florence, Italy<br />

12.30–12.40 N<strong>eu</strong>ropsychological correlates of l<strong>eu</strong>koaraiosis in patients with<br />

dementia<br />

P. Sucapane, F. Bologna, L. Fiorelli, S. Mearelli, C. Marini, A. Carolei,<br />

University of L'Aquila, Italy<br />

12.40–12.50 How useful are simple outcome measures for detecting dementia in<br />

large-scale clinical trials? Experience from the PROGRESS trial<br />

Y. Ratnasabapathy, C.A. Anderson, C. Tzourio, M. Jones, PROGRESS<br />

(Perindopril Protection against Recurrent Stroke Study) Collaborative Group,<br />

Clinical Trials Research Unit, University of Auckland, New Zealand<br />

12.50–13.00 Discussion<br />

13.00–14.30 Lunch and Poster Preview I<br />

(see pages 54–78)<br />

21


Scientific Programme Thursday, May 22, 2003<br />

14.30–16.00 Auditorium I<br />

22<br />

Joint Meeting on PFO Closure between the European Stroke<br />

Conference and Euro-PCR<br />

with direct satellite transmission between Paris and Valencia and live case<br />

demonstration from Rotterdam<br />

A Meeting of Hearts and Minds<br />

Bringing Closure to Cardiac Sources of Stroke<br />

Chair (Valencia): M.G. Hennerici, Germany<br />

Panelists: J. Bogousslavsky, Switzerland, P. Kramer, USA and H.P. Adams, USA<br />

Chair (Paris): H. Sievert, Germany<br />

Panelists: I. Palacios, USA, E. Eeckhout, Switzerland, N. Futrell, USA and<br />

M. Landzberg, USA<br />

14.30–14.50 Introduction – Scope of the problem<br />

J. Bogousslavsky, Switzerland<br />

A prescription a day keeps the implant away – Arguments for<br />

and against medical therapy vs. PFO closure and the utility of a patient<br />

registry, <strong>eu</strong>roPFOre<br />

M.G. Hennerici, Germany<br />

Make me whole, fix my heart, change my life – Acute and follow-up<br />

results in > 500 PFO closure patients<br />

H. Sievert, Germany<br />

14.50–15.20 Live PFO closure case transmission: Thoraxcenter Rotterdam<br />

(The Netherlands)<br />

P. Koudstaal, P. Serruys, M. Witsenburg, F. Meijboom, The Netherlands<br />

15.20–15.30 Marriage of hearts and minds – how to organise a PFO programme<br />

N<strong>eu</strong>rologist’s view – patient selection<br />

N. Futrell, USA<br />

Cardiologist’s view – treatment management<br />

P. Kramer, USA


15.30–15.50 Questions from Paris and Valencia panels and audiences<br />

Current recommendations, practices and future perspectives for<br />

patient management<br />

First randomised controlled trials<br />

H.P. Adams, USA<br />

Concluding remarks<br />

16.00–17.30 Poster Session I<br />

Chairs: S. Davis, Australia, W. Hacke, Germany and J. Ferro, Portugal<br />

(see pages 54–78)<br />

17.30–19.00 Auditorium I<br />

3 rd Academic Symposium of the Iberoamerican Cerebrovascular<br />

Diseases Society:<br />

Ischemic Stroke. New Approaches and Opportunities<br />

Chairs: J. Matías-Guiu, Spain and G. Saposnik, Argentina<br />

17.30–17.35 Introduction: Ischemic stroke. Rethinking the therap<strong>eu</strong>tic opportunities<br />

G. Saposnik, Argentina<br />

17.35–17.50 Emerging stroke risk factors and the role of inflammation.<br />

Can it be modified?<br />

O. del Bruto, Ecuador<br />

17.50–18.05 Anticoagulant and antiplatelet drugs in ischemic stroke prevention.<br />

Are they adequately used? Should they be reconsidered?<br />

O. Benavente, USA<br />

18.05–18.20 Reperfusion therapies in acute ischemic stroke.<br />

Experience in Iberoamerica. Fancies and fantasies.<br />

A. Massaro, Brazil<br />

23


Scientific Programme Thursday, May 22, 2003<br />

17.30–19.00 Auditorium I<br />

18.20–18.35 From homeostasis to n<strong>eu</strong>roprotection in acute ischemic stroke.<br />

Opportunity to an early intervention<br />

E. Díez Tejedor, Spain<br />

18.35–18.50 Vascular cognitive impairment. Can it be prevented and treated?<br />

V. Hachinski, Canada<br />

18.50–19.00 Discussion<br />

Closing remarks<br />

J. Matías-Guiu, Spain<br />

24<br />

Organised by the Iberoamerican Cerebrovascular Diseases Society with the<br />

help of the European Stroke Council. All participants have been invited by<br />

the Iberoamerican Cerebrovascular Diseases Society. Partially sponsored by<br />

Ferrer Group with a non-restrictive grant.


17.30–19.00 Auditorium II<br />

Satellite Symposium sponsored by Boehringer Ingelheim:<br />

Modern Stroke Management – Redefining Therap<strong>eu</strong>tic<br />

Options? From Acute Treatment to the PRoFESS Trial<br />

Chairs: G. Albers, USA and W. Hacke, Germany<br />

17.30–17.40 Introduction<br />

W. Hacke, Germany<br />

17.40–17.55 Departing into a new future of stroke therapy<br />

W. Hacke, Germany<br />

17.55–18.10 SITS-MOST (PMS study for rt-PA across Europe)<br />

N.G. Wahlgren, Sweden<br />

18.10–18.25 Combination antiplatelet therapy: do the risks/benefits differ<br />

for stroke vs. MI?<br />

G. Albers, USA<br />

18.25–18.40 The cerebrovascular connection to cardiovascular risk –<br />

the role of ARBs<br />

A. Coca, Spain<br />

18.40–18.55 Prevention Regimen of Effectively avoiding Second Strokes.<br />

The PRoFESS Trial<br />

H.C. Diener, Germany and R. Sacco, USA<br />

18.55–19.00 Concluding remarks<br />

G. Albers, USA and W. Hacke, Germany<br />

25


Scientific Programme Thursday, May 22, 2003<br />

17.30–19.00 Auditorium III<br />

17.00–17.35 Welcome<br />

26<br />

Satellite Symposium sponsored by Grupo Uriach:<br />

New Challenges of the Antithrombotic Treatment<br />

Chairs: M.D. Jiménez, Spain and I.L. Henriques, Portugal<br />

17.35–17.55 Contribution of Triflusal to secondary stroke prevention after TAPIRSS<br />

and TACIP studies<br />

J. Ferro, Portugal<br />

17.55–18.15 Counteraction of antihypertensive drugs effects by aspirin.<br />

Is the debate still going on?<br />

J. Redón, Spain<br />

18.15–18.35 Safety of antithrombotic drugs: an update<br />

A. Culebras, USA<br />

18.35–18.55 Stroke and dementia: new findings and future perspectives<br />

D. Muñoz, Spain<br />

18.55–19.00 Round table discussion


Friday, May 23, 2003<br />

08.00–08.30 Auditorium II<br />

Introduction European Society of N<strong>eu</strong>rosonology and<br />

Cerebral Hemodynamics 2003<br />

E.B. Ringelstein, Germany<br />

08.00–08.30 Auditorium III<br />

Introduction Early Surgery Trialists<br />

W. Sandmann, Germany<br />

08.30–10.00 Auditorium I<br />

Oral Session: Stroke Unit Concepts – Stroke Monitoring<br />

Chairs: A. Davalos, Spain and D. Toni, Italy<br />

08.30–08.40 Adjusting favourable outcomes following treatment of acute ischemic<br />

stroke as influenced by baseline severity of n<strong>eu</strong>rological impairments<br />

H. Adams, W. Hacke, A. Blumki, W. Clarke, M.D. Hansen, J. LeClerc,<br />

University of Iowa, USA<br />

08.40–08.50 Implementing acute stroke unit care: from clinical trial to clinical<br />

practice<br />

P. Langhorne, F. Wright, M. Shields, G. MacIntosh, D.J. Stott, Academic<br />

Section of Geriatric Medicine, University of Glasgow, United Kingdom<br />

08.50–09.00 Improved ADL performance after stroke unit care.<br />

Results from the Swedish national registry for quality assessment<br />

of acute stroke care<br />

A.B. Stegmayr, K. Asplund, E.L. Glader, K. Hulter-Åsberg, B. Norrving,<br />

A. Terént, P.O. Wester, Department of Public Health and Clinical Medicine,<br />

Sweden<br />

27


Scientific Programme Friday, May 23, 2003<br />

08.30–10.00 Auditorium I<br />

09.00–09.10 All patients with acute stroke should have access to stroke unit care.<br />

How to reach this goal?<br />

L. Candelise, G. Micieli, R. Sterzi, PROSIT, IRCCS Ospedale Maggiore<br />

Policlinico, Italy<br />

09.10–09.20 Effect of implementing stroke units in an area-wide concept on stroke<br />

care. The Baden-Württemberg Study<br />

M. Daffertshofer, M. Felsenstein, V. Schuchhardt, M.G. Hennerici, University<br />

Heidelberg, Universitätsklinikum Mannheim, Germany<br />

09.20–09.30 Telen<strong>eu</strong>rology to improve stroke care in rural areas – final results<br />

from the TESS project<br />

A. Wiborg, B. Widder, Bezirkskrankenhaus Guenzburg, Germany<br />

09.30–09.40 Variation in the management of acute physiological parameters after<br />

ischaemic stroke: a European perspective<br />

A. Bhalla, T. Mendel, P. Kolominsky-Rabas, P. H<strong>eu</strong>schmann, S. Eddine<br />

Megherbi, A. Czlonkowska, A. Kobayashi, M. Giroud, A. Rudd, C. Wolfe,<br />

Public Health Department, Guy's, King's and St Thomas' School of Medicine,<br />

United Kingdom<br />

09.40–09.50 The prognostic impact of arrhythmias and atrioventricular block in<br />

acute stroke<br />

A.H. Christensen, A.F. Christensen, G. Boysen, Bispebjerg Hospital, Denmark<br />

09.50–10.00 Impairment of respiratory muscle function in acute stroke patients<br />

F. Harraf, W.D. Man, G.F. Rafferty, M.I. Polkey, J. Moxham, L. Kalra, Guy's,<br />

King's and St Thomas' School of Medicine, King's College London,<br />

United Kingdom<br />

28


08.30–10.00 Auditorium II<br />

Oral Session: Diagnosis and Treatment with Ultrasound<br />

Chairs: N. Bornstein, Israel and D. Russell, Norway<br />

08.30–08.40 What is the nature and clinical importance of microembolic signals in<br />

carotid endarterectomy?<br />

T. Karapanayiotides, P. Ruchat, G. Darbellay, V. Kemeny, B. Piechowski-<br />

Jozwiak, J.M. Vesin, P.A. Despland, J. Bogousslavsky, G. Devuyst,<br />

Centre Hospitalier Universitaire Vaudois and EPFL, Switzerland<br />

08.40–08.50 Correlation of atherosclerotic changes between carotid, coronary and<br />

femoral arteries. Comparison of in vivo findings with autopsy<br />

L. Kerenyi, S. Molnar, M. Ritter, T. Magyar, E.B. Ringelstein, L. Csiba,<br />

University of Debrecen, Medical and Health Science Center, Hungary<br />

08.50–09.00 To what extent is pathological correlation in studies of imaging of<br />

carotid plaque compromised by unreliability of the histological<br />

assessment?<br />

J. Lovett, P. Gallagher, P. Rothwell, Stroke Prevention Research Unit,<br />

University Department of Clinical N<strong>eu</strong>rology, Radcliffe Infirmary,<br />

United Kingdom<br />

09.00–09.10 Intracranial stenosis in ischemic stroke: no relation with traditional<br />

atherosclerotic risk factors<br />

I. Henriques, I. Mendes, S. Mat<strong>eu</strong>s, S. Pires-Barata, L. Rebocho,<br />

Hospital Espirito Santo, Portugal<br />

09.10–09.20 Ultrasonic long-term follow-up of asymptomatic atherosclerotic<br />

stenosis of the middle cerebral artery<br />

C. Kremer, T. Schättin, R.W. Baumgartner, University Hospital Zürich,<br />

Switzerland<br />

09.20–09.30 Acceleration of MCA recanalisation by transcranial ultrasound:<br />

a therap<strong>eu</strong>tic option for patients not eligible for thrombolysis?<br />

J. Eggers, B. Koch, K. Meyer-Wiethe, University Hospital Lübeck, Germany<br />

29


Scientific Programme Friday, May 23, 2003<br />

08.30–10.00 Auditorium II<br />

09.30–09.40 Safety and efficacy of thrombotripsy – acceleration of thrombolysis by<br />

TCCS<br />

M. Bar, D. Skoloudik, P. Hradilek, D. Vaclavik, O. Skoda, Faculty Hospital<br />

Ostrava-Poruba, Czech Republic<br />

09.40–09.50 Characterisation of brain perfusion in acute stroke using flash<br />

destruction imaging with real-time power-pulse inversion ultrasound –<br />

a comparison with perfusion-weighted MRI<br />

R. Kern, F. Perren, A. Gass, M.G. Hennerici, S. Meairs, University of<br />

Heidelberg, Universitätsklinikum Mannheim, Germany<br />

09.50–10.00 Quantitative assessment of cerebral blood flow with real-time power<br />

pulse inversion contrast harmonic imaging<br />

S. Meairs, P. Horn, K. Schöneberger, R. Kern, F. Perren, M. Fatar, M.G. Hennerici,<br />

University of Heidelberg, Universitätsklinikum Mannheim, Germany<br />

08.30–10.00 Auditorium III<br />

30<br />

Oral Session: Vascular, Interventional and N<strong>eu</strong>rosurgery<br />

Chairs: M. Brown, United Kingdom and H. Mattle, Switzerland<br />

08.30–08.40 A systematic review of the risks of carotid endarterectomy in<br />

relation to the clinical indication and the timing of surgery<br />

R. Bond, K. Rerkasem, P.M. Rothwell, Stroke Prevention Research Unit,<br />

Radcliffe Infirmary, United Kingdom<br />

08.40–08.50 The acute and long-term results of carotid angioplasty<br />

K. Rabe, H. Goedel, R. Perron, I. Boesenberg, K.F. Beykirch, R. Theis,<br />

C. Rubel, W. Pfeil, H. Sievert, Cardiovascular Center Bethanien, Germany<br />

08.50–09.00 Spanish registry of carotid angioplasty and stenting. Preliminary report<br />

J. Vivancos-Mora, A. Gil-Nuñez, A. Gil-Peralta, D. <strong>Esc</strong>uder-Rubi, J. Matias-Guiu,<br />

J.R. Gonzalez-Marcos, R. Gonzalez-Santiago, F. Villoria-Medina,<br />

J. Sanchez-Ojanguren, J. Morera-Guitart, Stroke Project of the<br />

Cerebrovascular Study Group of the Spanish N<strong>eu</strong>rological Society,<br />

Stroke Unit, Hospital Universitario de la Princesa, Spain


09.00–09.10 Endovascular stent-assisted angioplasty for symptomatic intracranial<br />

vertebrobasilar artery stenosis and dissection<br />

T.H. Lee, D.H. Kim, B.H. Lee, H.J. Kim, S.H. Lee, D.S. Jung, Pusna National<br />

University Hospital, South Korea<br />

09.10–09.20 Endovascular stent-assisted angioplasty for symptomatic middle<br />

cerebral artery stenosis: feasibility and complication<br />

T.H. Lee, D.H. Kim, B.H. Lee, H.J. Kim, S.H. Lee, D.S. Jung, Pusan National<br />

University Hospital, South Korea<br />

09.20–09.30 Clinical presentation and surgical revascularisation procedures in<br />

Moyamoya disease and syndrome in Europe<br />

N. Khan, B. Schuknecht, A. Buck, E. Boltshauser, H.G. Imhof, Y. Yonekawa,<br />

University Hospital Zürich, Switzerland<br />

09.30–09.40 Stereotactic aspiration of deep intracerebral hematomas under<br />

computed tomographic control. A multicentric prospective<br />

randomised trial<br />

H. Hosseini, C. Leguerinel, M. Hariz, E. Melon, S. Palfi, P. Deck, A. Gaston,<br />

P. Cesaro, J.P. Nguyen, Chu Henri Mondor, France<br />

09.40–09.50 Ischaemic stroke due to the acute internal carotid artery occlusion:<br />

results of the emergent carotid disobliteration versus conservative<br />

treatment<br />

R. Herzig, M. Bar, I. Vlachova, B. Krupka, D. Sanak, P. Bachleda, P. Utikal,<br />

J. Machac, S. Burval, J. Mares, Stroke Center, Olomouc and Clinic of<br />

N<strong>eu</strong>rology, Czech Republic<br />

09.50–10.00 Prevention of n<strong>eu</strong>rological complications during carotid angioplasty<br />

with reversal of flow<br />

K. Rabe, H. Goedel, R. Perron, I. Boesenberg, K.F. Beykirch, R. Theis, C. Rubel,<br />

W. Pfeil, H. Sievert, Cardiovascular Center Bethanien, Germany<br />

10.00–10.30 Coffee Break<br />

31


Scientific Programme Friday, May 23, 2003<br />

10.30–11.30 Auditorium I<br />

32<br />

Oral Session:<br />

Acute Stroke – Symptoms and Clinical Diagnosis<br />

Chairs: L. Caplan, USA and B. Norrving, Sweden<br />

10.30–10.40 Comparison of clinical classification and diffusion-weighted MRI for<br />

acute stroke localisation<br />

K. Murray, C. Santosh, I. Bone, K. Muir, Institute of N<strong>eu</strong>rological Sciences,<br />

Southern General Hospital, United Kingdom<br />

10.40–10.50 DWI signal intensities are different in TIA as compared to stroke<br />

K. Winbeck, K. Bruckmaier, T. Etgen, K. Forster, B. Conrad, D. Sander,<br />

Technical University of Munich, Germany<br />

10.50–11.00 A simple three item stroke score: comparison with the NIHSS score<br />

and prediction of vessel occlusion<br />

O.C. Singer, R.D. Mesnil de Rochemont, H. Lanfermann, C. Foerch, M. Sitzer,<br />

T. N<strong>eu</strong>mann-Haefelin, J.W. Goethe University, Germany<br />

11.00–11.10 Clinical characteristics of transient n<strong>eu</strong>rologic deficits of chronic<br />

subdural haematoma<br />

H.G. Sunku, Hinchingbrooke Hospital, United Kingdom<br />

11.10–11.20 Cognitive and behavioural aspects affecting early referral of acute<br />

stroke patients; Bystander’s knowledge of signs and symptoms of<br />

stroke<br />

M. Shah, K. Makinde, D. Schelewa, P. Thomas, Prince Philip Hospital,<br />

United Kingdom<br />

11.20–11.30 Telemedicine for stroke management – feasibility and first<br />

experience using multimedia systems in an acute care setting<br />

R. Handschu, B. Tomandl, R.R. Littmann, J.G. Heckmann,<br />

B. N<strong>eu</strong>ndörfer, M. Scibor, University of Erlangen, Germany


10.30–11.30 Auditorium II<br />

Oral Session: Venous Diseases<br />

Chairs: M.G. Bousser, France and A. Czlonkowska, Poland<br />

10.30–10.40 Is smoking a risk factor for cerebral vein and dural sinus thrombosis<br />

in oral contraceptive users? A case control study<br />

A. Ciccone, A. Gatti, C. Coppola, S. Iurlaro, E. Agostani, G. Boncoraglio,<br />

Stroke Unit Azienda Ospedaliera Niguarda Ca' Granda, Italy<br />

10.40–10.50 Jugular valve incompetence in transient global amnesia –<br />

an epiphenomenon?<br />

S.J. Schreiber, F. Doepp, R. Klingebiel, J.M. Valdueza, University Hospital<br />

Charité, Germany<br />

10.50–11.00 N<strong>eu</strong>rological worsening in the acute phase of cerebral venous<br />

thrombosis in ISCVT (International Study on Cerebral Venous<br />

Thrombosis)<br />

I. Crassard, P. Canhão, J.M. Ferro, M.G. Bousser, F. Barinagarrementeria,<br />

J. Stam, ISCVT, Hospital Santa Maria, Portugal<br />

11.00–11.10 Clinical outcome and screening of prothrombotic factors in cerebral<br />

venous thrombosis<br />

L. Derex, S. Cakmak, M. Berruyer, N. Nighoghossian, F. Philippeau,<br />

P. Adeleine, M. Hermier, J.C. Froment, P. Trouillas, Hôpital N<strong>eu</strong>rologique, France<br />

11.10–11.20 N<strong>eu</strong>rological and cognitive long-term outcome of cerebral venous<br />

sinus thrombosis in childhood: report of three cases<br />

G. Buccino, G. Cossu, A. De Fanti, I. Patteri, G.C. Izzi, D. Mancia,<br />

University of Parma, Italy<br />

11.20–11.30 The long-term prognosis of cerebral vein and dural sinus thrombosis:<br />

ISCVT results<br />

J.M. Ferro, J. Stam, M.G. Bousser, F. Barinagarrementeria, P. Canhão, ISCVT,<br />

Hospital Santa Maria, Portugal<br />

33


Scientific Programme Friday, May 23, 2003<br />

10.30–12.30 Auditorium III<br />

34<br />

Oral Session: Experimental Studies<br />

Chairs: L. Hirt, Switzerland and K. Overgaard, Denmark<br />

10.30–10.40 Ischemia of the external carotid artery territory influences outcome in<br />

the endovascular filament model of middle cerebral artery occlusion<br />

in the rat<br />

M. Dittmar, T. Spruss, G. Schuierer, G.W. Ickenstein, M. Horn, Department of<br />

N<strong>eu</strong>rology, University of Regensburg, Germany<br />

10.40–10.50 Hyperbaric Oxygenation (HBO) converts n<strong>eu</strong>ronal cell death from<br />

necrosis to apoptosis in transient focal cerebral ischemia in the<br />

infarct core in rats<br />

C.C. <strong>Esc</strong>henfelder, M. Lou, T. Herdegen, G. D<strong>eu</strong>schl, Christian-Albrechts<br />

University, Germany<br />

10.50–11.00 Evolving relations between cerebral blood flow and oxygen<br />

metabolism after middle cerebral artery occlusion in the porcine<br />

chronic stroke model<br />

H. Watanabe, A. Olsen, C. Bjarkam, A. Rodell, D. Zeilder, A. Blankholm,<br />

L. Ostergaard, P. Coming, A. Gjedde, Center of Functionally Integrative<br />

N<strong>eu</strong>roscience, Aarhus University, Denmark<br />

11.00–11.10 Stabilisation of cellular proliferation into steady state over the<br />

arterial filtration struts of the diverter – a novel device for stroke<br />

prevention<br />

D. Tanne, O. Yodfat, D. Harris, Y. Assaf, J. Leor, D. Bushi, Y. Grad,<br />

MindGuard Medical Devices, Israel<br />

11.10–11.20 Celecoxib induces functional recovery after intracerebral<br />

hemorrhage with reduction of brain edema and perihematomal<br />

cell death<br />

K. Chu, K.H. Jung, S.W. Jeong, M. Kim, J.K. Roh, Seoul National University<br />

Hospital, South Korea


11.20–11.30 Hypothalamic injury and subsequent hyperthermia confounds<br />

n<strong>eu</strong>roprotective drugs studies – a comparison between the suture<br />

and the macrosphere MCAO technique<br />

T. Gerriets, E. Stolz, M. Walberer, G. Bachmann, M. Fisher, M. Kaps,<br />

University Giessen, Germany<br />

11.30–11.40 Cortical expression of proinflammatory cytokines in different<br />

preconditioning paradigms in focal brain ischemia<br />

J. Pera, M. Zawadzka, B. Kaminska-Kaczmarek, A. Szczudlik,<br />

Jagiellonian University, Poland<br />

11.40–11.50 Effective emboli diversion by a novel permanent device for prevention<br />

of embolic stroke<br />

Y. Asaff, J. Schneiderman, D. Bushi, J. Leor, D. Harris, B. Nishri, O. Oz,<br />

D. Tanne, Y. Grad, MindGuard Medical Devices, Israel<br />

11.50–12.00 Natural time course of brain edema in the hyperacute phase of<br />

experimental stroke – MRI studies with an in-bore MCA occlusion<br />

technique in rats<br />

T. Gerriets, E. Stolz, M. Walberer, C. Mueller, A. Kluge, A. Bachmann, M. Kaps,<br />

G. Bachmann, University Giessen and Kerckhoff Clinic Bad Nauheim, Germany<br />

12.00–12.10 Minocycline reduces infarct size and rate of hemorrhagic<br />

transformations in SOD2-KO mice<br />

C. Maier, L. Hsieh, F. Yu, P. Chan, Stanford University, USA<br />

12.10–12.20 Determination of the hypothermic component in n<strong>eu</strong>roprotection by<br />

cannabinoids in experimental stroke<br />

P.K. Bonfils, J. Reith, L. Thatt, F.F. Johansen, University of Copenhagen,<br />

Molecular N<strong>eu</strong>ropathology Group, Denmark<br />

12.20–12.30 Short and long-term effects of brief transient middle cerebral artery<br />

occlusion (MCA-o) on gait and working memory in the Wistar rat<br />

C. Sarti, L. Bartolini, D. Inzitari, L. Pantoni, Department of N<strong>eu</strong>rological and<br />

Psychiatric Sciences, University of Florence, Italy<br />

35


Scientific Programme Friday, May 23, 2003<br />

11.30–12.30 Auditorium I<br />

36<br />

Oral Session: Acute Stroke – Treatment Concepts<br />

Chairs: F. Aichner, Austria and M. Kaste, Finland<br />

11.30–11.40 The usefulness of clinical DWI mismatch in the treatment of acute<br />

ischemic stroke with reperfusion therapies<br />

A. Dávalos, R. Leira, S. Pedraza, M. Blanco, J. Serena, Y. Silva,<br />

M. Castellanos, J. Castillo, Hospital Universitari Doctor Josep Trueta, Spain<br />

11.40–11.50 Clinical and radiological predictors of recanalisation and outcome<br />

in 40 patients with acute basilar artery occlusion treated with<br />

intra-arterial thrombolysis<br />

M. Arnold, K. Nedeltchev, R.W. Baumgartner, L. Remonda, G. Schroth,<br />

T.J. Loher, F. Stepper, M. Sturzenegger, H.P. Mattle, University of Berne,<br />

Switzerland<br />

11.50–12.00 Thrombin-activable fibrinolysis inhibitor (TAFI) level is related to<br />

t-PA-induced recanalisation resistance after ischemic stroke<br />

J. Montaner, J. Monasterio, C.A. Molina, M. Ribó, J.F. Arenillas, F. Pujadas,<br />

J. Alvarez-Sabín, N<strong>eu</strong>rovascular Research Laboratory, Stroke Unit,<br />

Vall d'Hebron Hospital, Spain<br />

12.00–12.10 Degree of tPA-induced proximal MCA recanalisation differs among<br />

stroke subtypes<br />

C.A. Molina, E. Santamarina, J. Montaner, J.F. Arenillas, M. Ribo, R. Huertas,<br />

J. Mauriño, J. Alvarez-Sabin, Hospital Vall d'Hebron, Spain<br />

12.10–12.20 Beyond the three hour time-window: multivariable patient-selection<br />

for thrombolytic therapy in acute ischemic stroke<br />

D. Kent, R. Ruthazer, E. Bluhmki, H. Selker, Division of Clinical Care Research,<br />

Tufts New England Medical Center, USA<br />

12.20–12.30 Improved disability endpoint selection for use in acute stroke trials<br />

F.B. Young, K.R. Lees, C.J. Weir, University of Glasgow, United Kingdom


11.30–12.30 Auditorium II<br />

Oral Session: Meta-Analysis and Review Papers<br />

Chairs: G. Donnan, Australia and C. Warlow, United Kingdom<br />

11.30–11.40 High morbidity and mortality due to endarterectomy for asymptomatic<br />

carotid stenosis<br />

R. Bond, K. Rerkasem, P.M. Rothwell, Stroke Prevention Research Unit,<br />

Radcliffe Infirmary, United Kingdom<br />

11.40–11.50 Antithrombotic drugs for carotid artery dissection – a Cochrane<br />

review (update)<br />

A.P. Lyrer, S. Engelter, University Hospital Basel, N<strong>eu</strong>rological Clinic and<br />

Stroke Unit, Switzerland<br />

11.50–12.00 Risk factors for intracerebral hemorrhage in the general population,<br />

a systematic review<br />

M.J. Ariesen, S.P. Claus, G.J.E. Rinkel, A. Algra, University Medical Centre<br />

Utrecht, The Netherlands<br />

12.00–12.10 Antiplatelet therapy for preventing stroke after carotid<br />

endarterectomy – a Cochrane review<br />

S. Engelter, P. Lyrer, University Hospital Basel,<br />

N<strong>eu</strong>rological Clinic and Stroke Unit, Switzerland<br />

12.10–12.20 The Cochrane Library: a useful resource for informing evidence-based<br />

stroke care<br />

P. Sandercock, H. Fraser, B. Thomas, A. McInnes, S. Dixon, The Cochrane<br />

Stroke Review Group, University of Edinburgh, United Kingdom<br />

12.20–12.30 Systematic review of nitric oxide donors and L-arginine in<br />

experimental stroke: effects on infarct size and cerebral blood flow<br />

M. Willmot, S. Murphy, J. Leonardi-Bee, P. Bath, Institute of N<strong>eu</strong>rosciences,<br />

University of Nottingham, United Kingdom<br />

12.30–14.00 Lunch and Poster Preview II<br />

(see pages 79–105)<br />

37


Scientific Programme Friday, May 23, 2003<br />

14.00–16.00 Auditorium I<br />

38<br />

Oral Session: Acute Stroke Outcome<br />

Chairs: M. Daffertshofer, Germany and P. Koudstaal, The Netherlands<br />

14.00–14.10 Safe Implementation of Thrombolysis in Stroke (SITS) – results from<br />

the first two years of an Internet-based register of thrombolysis in<br />

stroke<br />

N. Wahlgren, A. Davalos, C. Fieschi, M. Grond, W. Hacke, M. Kaste, V. Larrue,<br />

K.R. Lees, Karolinska Hospital, Sweden<br />

14.10–14.20 Blood pressure course during the acute phase of stroke is strongly<br />

associated with stroke outcome: tertiary analysis of GAIN International<br />

F. Fazekas, S. Aslanyan, C.J. Weir, S. Horner, K.R. Lees, GAIN International<br />

Steering Committee and Investigators, Karl-Franzens University Graz, Austria<br />

14.20–14.30 Predictictive role of 24-hour blood pressure values on stroke mortality<br />

G. Tsivgoulis, A. Synetos, K. Spengos, E. Manios, V. Kotsis, E. Vassiliadi,<br />

K. Vemmos, University of Athens, Medical School, Greece<br />

14.30–14.40 Clinical symptoms and early outcome in MR-DWI characterised<br />

isolated cerebellar infarction<br />

E. Grips, O. Sedlaczek, M. Fritzinger, M. Daffertshoffer, M.G. Hennerici,<br />

Dept. of N<strong>eu</strong>rology Mannheim, University of Heidelberg, Germany<br />

14.40–14.50 Vertebral artery stenosis: a surprisingly benign condition<br />

L. Coward, M. Brown, Stroke Research Group, Institute of N<strong>eu</strong>rology,<br />

University College London, United Kingdom<br />

14.50–15.00 Long-term follow-up in patients with acute spinal cord infarction<br />

syndrome (ASCIS)<br />

K. Nedeltchev, M. Arnold, H.P. Mattle, T.J. Loher, F. Stepper, M. Sturzenegger,<br />

University of Bern, Switzerland


15.00–15.10 Risk of cerebrovascular and cardiac mortality after major stroke or<br />

minor/lacunar stroke: a review of community-based, follow-up<br />

studies in Europe<br />

F. Guillot, Sanofi-Synthelabo Recherche, France<br />

15.10–15.20 Predictors for in-hospital-mortality after ischemic stroke in routine<br />

clinical practice. The German Stroke Registers Study Group<br />

P.U. H<strong>eu</strong>schmann, P.L. Kolominsky-Rabas, B. Misselwitz, C. Leffmann,<br />

P. Hermanek, K. Berger, German Stroke Registers Study Group,<br />

Institute of Epidemiology and Social Medicine, Germany<br />

15.20–15.30 Long-term prognosis of patients with a complete MCA territory<br />

infarction treated with decompressive hemicraniectomy<br />

P. Erban, C. Woertgen, R. Luerding, G. Ickenstein, U. Bogdahn, M. Horn,<br />

Departments of N<strong>eu</strong>rology and N<strong>eu</strong>rosurgery, University of Regensburg, Germany<br />

15.30–15.40 What determines quality of life long-term after stroke?<br />

M. Patel, K. Tilling, C. McKevitt, A.G. Rudd, C.D.Wolfe, Dept. of Public Health<br />

Sciences, GKT School of Medicine, King's College London, United Kingdom<br />

15.40–15.50 Long-term evolution of young patients (pts) with stroke:<br />

individualisation of a high risk population<br />

A.A. De Windt, S.M. Jeangette, M. Pandolfo, S.A. Blecic, Erasme Hospital,<br />

Belgium<br />

15.50–16.00 Predictors of disabling fatigue in “non-disabling” stroke<br />

F. Staub, J.M. Annoni, S. Gramigna, J. Bogousslavsky, Centre Hospitalier<br />

Universitaire Vaudois, Switzerland<br />

39


Scientific Programme Friday, May 23, 2003<br />

14.00–16.00 Auditorium II<br />

40<br />

Oral Session: Recovery and Rehabilitation<br />

Chairs: A. Carolei, Italy and P. Langhorne, United Kingdom<br />

14.00–14.10 Intensive early physiotherapy combined with dexamphetamine<br />

treatment in severe stroke. A randomised controlled study<br />

L. Martinsson, S. Eksborg, N.G. Wahlgren, Clinical N<strong>eu</strong>rosciences,<br />

Karolinska Institute, Sweden<br />

14.10–14.20 Life after stroke: multicentre trial of psychosocial interventions after<br />

stroke<br />

M. Leathley, S. Fall, A. Sharma, C. Watkins, D. Barer, University of Central<br />

Lancashire, United Kingdom<br />

14.20–14.30 A randomised trial to evaluate improved routine communication to<br />

patients and carers after stroke<br />

J.E. Smith, A. Forster, J.B. Young, Bradford Elderly Care and Rehabilitation<br />

Research Department (BECARRD), St Luke's Hospital, United Kingdom<br />

14.30–14.40 A family support organiser for stroke patients and their carers:<br />

intervention design and results of a randomised controlled trial<br />

K. Tilling, C. McKevitt, C. Coshall, K. Daneski, C. Wolfe, Department of<br />

Public Health Sciences, King's College London, United Kingdom<br />

14.40–14.50 Serial investigation of n<strong>eu</strong>ronal reorganisation in acute stroke<br />

patients using fMRI and DTI techniques<br />

F. Zelaya, V. Ng, A. Evans, M. Brammer, C. Andrew, D. Jones, D. Lythgoe,<br />

J. Grey, S. Williams, L. Kalra, Guy's, King's & St Thomas' School of Medicine,<br />

King's College, United Kingdom<br />

14.50–15.00 Correspondence of therapy-induced changes observed in fMRI and<br />

movement-related cortical potentials in chronic stroke subjects;<br />

preliminary data<br />

A.I.M. Tarkka, M. Könönen, E. Mervaala, K. Pitkänen, J. Sivenius, Brain<br />

Research and Rehabilitation Center, N<strong>eu</strong>ron and Kuopio University Hospital,<br />

Finland


15.00–15.10 The relationship between motor related brain activations and<br />

recovery after stroke: a cross sectional fMRI study<br />

N.S. Ward, M.M. Brown, A.J. Thompson, R.S. Frackowiak, Wellcome<br />

Department of Imaging N<strong>eu</strong>roscience, Institute of N<strong>eu</strong>rology, United Kingdom<br />

15.10–15.20 The impact of right cerebral hemisphere damage on the use of<br />

gesture and prosody for communication<br />

N. Cocks, K. Hird, K. Kirsner, Curtin University of Technology, Australia<br />

15.20–15.30 Constraint-induced movement therapy for chronic stroke patients<br />

K. Pitkänen, I.M. Tarkka, J. Sivenius, Brain Research and Rehabilitation Center<br />

N<strong>eu</strong>ron, Finland<br />

15.30–15.40 Effect of age on access to stroke care in England, Wales and Northern<br />

Ireland: results from the National Sentinel Audits of Stroke 1998–2002<br />

A.G. Rudd, A. Hoffman, D. Lowe, P. Irwin, M. Pearson, Royal College of<br />

Physicians London, United Kingdom<br />

15.40–15.50 Amphetamine or physical therapy promote rehabilitation in a rat<br />

embolic stroke model<br />

R.S. Rasmussen, K. Overgaard, E.S. Hildebrandt-Eriksen, G. Boysen,<br />

N<strong>eu</strong>rovascular Research Laboratory, Copenhagen University Hospital,<br />

Denmark<br />

15.50–16.00 Intrathecal baclofen – a valid option in rehabilitation of stroke<br />

patients<br />

P. Abr<strong>eu</strong>, E. Azevedo, N. Fontes, J. Correia, N. Marçal, Hospital S. João,<br />

Portugal<br />

41


Scientific Programme Friday, May 23, 2003<br />

14.00–16.00 Auditorium III<br />

42<br />

Oral Session: Cardiovascular Topics: PFO and IMT<br />

Chairs: J.L. Mas, France and N. Futrell, USA<br />

14.00–14.10 Percutaneous left atrial appendage occlusion to prevent stroke in<br />

patients with atrial fibrillation: early and mid-term results<br />

S.H.U. Ostermayer, M. Reschke, T. Trepels, K. Billinger, M. Lesh, T. Nakai,<br />

H. Sievert, Cardiovascular Center Bethanien, Germany<br />

14.10–14.20 Association between right-to-left shunts and brain lesions in sport<br />

divers<br />

T. Gerriets, K. Tetzlaff, A. Hutzelmann, T. Liceni, G. Kopiske, N. Struck,<br />

M. R<strong>eu</strong>ter, M. Kaps, Justus-Liebig University, Germany<br />

14.20–14.30 Differential stroke pattern on diffusion MRI among PFO patients with<br />

and without atrioseptal an<strong>eu</strong>rysm<br />

E. Santamarina, C.A.Molina, J.F. Arenillas, J. Montaner, M. Ribo, R. Huertas,<br />

J. Alvarez-Sabin, A. Rovira, E. Grive, Hospital Vall d'Hebron, Spain<br />

14.30–14.40 Transcatheter closure of patent foramen ovale for secondary prevention<br />

of TIAs and strokes: acute results and follow up in 597 patients<br />

K. Billinger, M. Reschke, T. Trepels, S. Ostermayer, E. Zadan, K. Horvath,<br />

H. Sievert, Cardiovascular Center Bethanien, Germany<br />

14.40–14.50 Atrial fibrillation following catheter closure of interatrial<br />

communications: single centre experience in 1,184 patients<br />

T. Trepels, S. Ostermayer, K. Billinger, H. Sievert, Cardiovascular Center<br />

Bethanien, Germany<br />

14.50–15.00 Patent foramen ovale with presumed paradoxical embolism:<br />

percutaneous closure or antithrombotic therapy?<br />

V. Thijs, M. Schrooten, W. Budts, UZ L<strong>eu</strong>ven, Belgium<br />

15.00–15.10 Magnitude of intracranial artery disease in severe coronary heart<br />

disease patients<br />

J.I. Tembl, M.A. Arnau, A. Lago, E. Fages, I. Boscá, A. Osa, M. Palencia,<br />

Hospital Universitari La Fe Valencia, Spain


15.10–15.20 Oral anticoagulation in patients with atrial fibrillation: influence of<br />

pre-existing dementia on prescription before stroke in practice<br />

C. Lefebvre, D. Deplanque, H. Henon, F. Pasquier, D. Leys, University of Lille,<br />

France<br />

15.20–15.30 Comparison of in vivo carotid IMT and carotid wall thickness<br />

measured with a novel method (comparison of in vivo and<br />

post-mortem data)<br />

S. Molnar, L. Kerenyi, M. Ritter, T. Magyar, E.B. Ringelstein, L. Csiba,<br />

University of Debrecen, Medical and Health Science Center, Hungary<br />

15.30–15.40 Is the common carotid artery intima media thickness predictor of<br />

stroke outcome?<br />

P. Talelli, J. Ellul, G. Gioldasis, G. Terzis, A. Chrisanthopoulou,<br />

T. Papapetropoulos, University of Patras, Greece<br />

15.40–15.50 Gene polymorphisms causing mild hyperhomocysteinemia and<br />

thrombophilia – possible risk factors for spontaneous cervical artery<br />

dissections?<br />

U. Mueller, T. Wiest, A. Grau, T. Brandt, C. Grond-Ginsbach, University of<br />

Heidelberg, Germany<br />

15.50–16.00 Fibrinogen and fibrinolysis in carotid arterial wall in patients with<br />

advanced atherosclerosis<br />

J. Krupinski, E. Catena, R. Vila, M. Cairols, L. Badimon, F. Rubio,<br />

Hospital Universitario de Bellvitge, Spain<br />

16.00–17.30 Poster Session II<br />

Chairs: L. Csiba, Hungary, T. Els, Germany, A. Hetzel, Germany and<br />

K. Lees, United Kingdom<br />

(see pages 79–105)<br />

43


Scientific Programme Friday, May 23, 2003<br />

17.30–19.00 Auditorium II<br />

44<br />

Satellite Symposium organised by EUSI:<br />

Controversies in Stroke Management<br />

Chair: W. Hacke, Germany<br />

Carotid stenting<br />

Standard of care<br />

M. Forsting, Germany<br />

Unproved experimental procedure<br />

D. Leys, France<br />

Hypothermia<br />

The most promising n<strong>eu</strong>roprotection<br />

T.S. Olson, Denmark<br />

A risky, difficult and experimental procedure<br />

S. Schwab, Germany<br />

Antithrombotic combination therapy<br />

Ready for prime time<br />

H.C. Diener, Germany<br />

Careful with extrapolation<br />

P. Bath, United Kingdom


17.30–19.00 Auditorium III<br />

Stroke Units in Europe: Linking Practice with Evidence<br />

Joint Symposium Organised in Collaboration with the<br />

Cochrane Stroke Group, Stroke Unit Trialists Collaboration<br />

and European Stroke Unit Group<br />

Review of admission/discharge policy and intensity of care for acute<br />

stroke around Europe<br />

Chairs: P. Sandercock, United Kingdom and A. Czlonkowska, Poland<br />

17.30–17.35 Introduction<br />

L. Candelise, Italy<br />

17.35–17.50 Lessons from the stroke unit trials on admission/discharge policy and<br />

intensity of care for acute stroke<br />

P. Langhorne for the SUTC, United Kingdom<br />

17.50–18.00 The Swedish experience<br />

K. Asplund, Sweden<br />

18.00–18.10 The Italian experience<br />

R. Sterzi for PROSIT collaborators, Italy<br />

18.10–18.50 Examples from around Europe<br />

Up to 7 brief presentations, selected from poster submissions<br />

18.50–19.00 Panel discussion (implementing the evidence) and concluding<br />

remarks to identify key research questions<br />

Co-Chairs: S. Ricci, Italy and C. Wolfe, United Kingdom<br />

Panelists: M. Brainin, Austria, J. Bogousslavsky, Switzerland, G. Boysen,<br />

Denmark, D. Bereczki, Hungary, O. Busse, Germany, M. Dennis,<br />

United Kingdom, J. Ferro, Portugal, M. Hommel, France, B. Indredavik,<br />

Norway, G. Micieli, Italy<br />

45


Scientific Programme Saturday, May 24, 2003<br />

08.30–10.30 Auditorium I<br />

46<br />

Oral Session: ICH and SAH<br />

Chairs: S. Blecic, Belgium and J. van Gijn, The Netherlands<br />

08.30–08.40 Headache and risk of subarachnoid haemorrhage (SAH):<br />

a population-based case-control study<br />

K.N. Carter, N. Anderson, K. Jamrozik, G. Hankey, C.S. Anderson, Australasian<br />

Co-operative Research on Subarachnoid Haemorrhage Study (ACROSS) Group,<br />

Clinical Trials Research Unit, University of Auckland, New Zealand<br />

08.40–08.50 Magnetic resonance imaging in experimental subarachnoid<br />

haemorrhage<br />

W. van den Bergh, A. Algra, G. Rinkel, Department of N<strong>eu</strong>rosurgery,<br />

UMC Utrecht, The Netherlands<br />

08.50–09.00 Repeated screening for intracranial an<strong>eu</strong>rysms in familial<br />

subarachnoid haemorrhage<br />

M.J. Wermer, G.J.Rinkel, Rudolf Magnus Institute for N<strong>eu</strong>rosciences,<br />

University Medical Centre Utrecht, The Netherlands<br />

09.00–09.10 Electrocardiographic abnormalities and serum magnesium in patients<br />

with subarachnoid hemorrhage<br />

W. van den Bergh, A. Algra, G. Rinkel, UMC Utrecht, The Netherlands<br />

09.10–09.20 Psychiatric disturbances after subarachnoid haemorrhage<br />

C. Menger, L. Caeiro, J.M. Ferro, R. Albuquerque, M.L. Figueira, Hospital<br />

Santa Maria, Portugal<br />

09.20–09.30 DD genotype of ACE gene is a risk factor for spontaneous<br />

intracerebral haemorrhage<br />

A. Slowik, T. Dziedzic, J. Pera, W. Turaj, P. Szermer, L. Sobanska,<br />

A. Borratynska, D.A. Figlewicz, A. Szczudlik, Jagiellonian University, Poland<br />

09.30–09.40 No evidence of “ischemic penumbra” in intracerebral hemorrhage:<br />

a PWI/DWI study<br />

K. Butcher, M.M. Parsons, T. Baird, P. Desmond, B. Tress, S. Davis,<br />

Royal Melbourne Hospital, Australia


09.40–09.50 Risk of ICH and arterial versus cardiac origin of cerebral ischaemia:<br />

analysis of individual patient data from 9 trials: an update<br />

M.J. Ariesen, A. Algra, P.J. Koudstaal, P.M. Rothwell, C. VanWalraven,<br />

Dutch TIA, SPIRIT, UK TIA, EAFT, AFASAKI-II, SPAF I-II and PATAF Study Groups,<br />

University Medical Centre Utrecht, The Netherlands<br />

09.50–10.00 Linear hyperintensity objects in the cerebral white matter may predict<br />

the hypertensive intracerebral hemorrhage<br />

M. Hiroki, K. Miyashita, S. Hirai, H. Fukuyama, Human Brain Research Center,<br />

Kyoto University Graduate School of Medicine, Japan<br />

10.00–10.10 Temporal profile of matrix metalloproteinases (MMPS) and their<br />

inhibitors (TIMPS) after spontaneous intracerebral hemorrhage.<br />

Relationship to clinical and radiological outcome<br />

J. Alvarez-Sabín, S. Abilleira, P. Delgado, C.A. Molina, J.F. Arenillas,<br />

E. Santamarina, J. Monasterio, J. Montaner, N<strong>eu</strong>rovascular Research<br />

Laboratory, Stroke Unit, Vall d'Hebron Hospital, Spain<br />

10.10–10.20 Safety of cessation or reinstitution of anticoagulants in patients with<br />

intracranial hemorrhage and a high cardio embolic risk<br />

N. Akhtar, N. Dean, H. Lari, K. Khan, M. Saqqur, F. Orourke, M. Moratuglu,<br />

A. Shuaib, Stroke Unit, University of Alberta Hospital, Canada<br />

10.20–10.30 Safety and preliminary efficacy of activated recombinant factor VII<br />

(Novoseven ® ) in acute intracerebral haemorrhage<br />

T. Steiner, S. Mayer, N. Brun, University of Heidelberg, Germany<br />

47


Scientific Programme Saturday, May 24, 2003<br />

08.30–10.30 Auditorium II<br />

48<br />

Oral Session: N<strong>eu</strong>roimaging: MRI and fMRI<br />

Chairs: R. von Kummer, Germany and J.C. Baron, United Kingdom<br />

08.30–08.40 PET and DW/PW-MRI in acute stroke: identification of impaired<br />

n<strong>eu</strong>ronal integrity and cerebral hypoperfusion<br />

J. Sobesky, U. Smekal, L. Kracht, F. Lehnhardt, C. Dohmen, M. Neveling,<br />

W.D. Heiss, University of Cologne and Max Planck Institute for N<strong>eu</strong>rologic<br />

Research, Germany<br />

08.40–08.50 Assessment of infratentorial acute ischemic stroke with<br />

diffusion-weighted-imaging (DWI)<br />

C. Lie, J. Hirsch, S. Schwenk, K. Szabo, M.G. Hennerici, A. Gass,<br />

Universitätsklinikum Mannheim, Germany<br />

08.50–09.00 Inter-ictal cellular energy reserves in migrain<strong>eu</strong>rs with prolonged<br />

aura or coma and migrainous stroke: a brain 31P-MR spectroscopy<br />

study<br />

U. Schulz, A.M. Blamire, R.G. Corkill, P. Styles, P. Davies, P.M. Rothwell,<br />

Stroke Prevention Research Unit, University Department of Clinical N<strong>eu</strong>rology,<br />

United Kingdom<br />

09.00–09.10 PWI maps as signatures of early clinical outcome and infarct<br />

volume in acute ischemic stroke<br />

S. Pedraza, C. Guergue, J. Mendez, J. Vera, Y. Silva, A. Davalos,<br />

Hospital Josep Trueta, Spain<br />

09.10–09.20 MR diffusion and perfusion abnormalities in ischaemic stroke –<br />

patterns of sub-regional change and tissue recovery<br />

A.C.S. Rivers, P.A. Armitage, T. Carpenter, P.J. Hand, M.S. Dennis,<br />

J.M. Wardlaw, University of Edinburgh, United Kingdom<br />

09.20–09.30 Diffusion-weighted MR-imaging during the early phase of global<br />

cerebral hypoxia: a predictor for clinical outcome?<br />

T. Els, J. Klisch, R. Kubalek, J. Kassubek, M. Herpers, C.H. Lucking,<br />

University of Freiburg, Germany


09.30–09.40 Window narrowing – a new method for standardised assessment of<br />

the ischemic centre in CT based brain perfusion maps<br />

D.G. Nabavi, S.P. Kloska, E.M. Nam, A. Allroggen, E. Klotz, W. Heindel,<br />

E.B. Ringelstein, University Hospital of Münster, Germany<br />

09.40–09.50 The ischaemic penumbra in white and grey matter of brain after<br />

ischaemic stroke; an 18FMISO PET study<br />

A.L.E. Falcao, D.C. R<strong>eu</strong>tens, R. Markus, T. Phan, P. Wright, S.J. Read,<br />

H. Tochon-Danguy, J. Sachinidis, D.W. Howells, G.A. Donnan,<br />

National Stroke Research Institute, Australia<br />

09.50–10.00 Hemodynamic assessment by diffusion-weighted MRI, proton MR<br />

spectroscopic imaging and SPECT in symptomatic patients due to the<br />

occlusive major-vessel<br />

K. Kamada, K. Mitsumori, T. Shogo, I. Yoshinobu, Chitose City Hospital, Japan<br />

10.00–10.10 Plasmatic level of matrix metalloproteinase-9 predicts the extent of<br />

diffusion-weighted image lesion in human hyperacute stroke<br />

M. Ribó, J. Montaner, A. Rovira, C.A. Molina, J. Monasterio, J. Arenillas,<br />

P. Chacón, J. Alvarez-Sabín, N<strong>eu</strong>rovascular Research Laboratory, Stroke Unit,<br />

Vall d'Hebron Hospital, Spain<br />

10.10–10.20 Visualisation of cerebral ischemia without contrast agent using<br />

power pulse-inversion harmonic imaging<br />

F. Perren, R. Kern, A. Gass, M.G. Hennerici, S. Meairs, University of<br />

Heidelberg, Universitätsklinikum Mannheim, Germany<br />

10.20–10.30 Noninvasive measurement of regional cerebral blood flow by near<br />

infrared spectroscopy and indocyaningreen dye dilution<br />

E. Keller, A. Nadler, H. Alkadhi, S. Kollias, Y. Yonekawa, P. Niederer,<br />

University Hospital Zürich, Switzerland<br />

49


Scientific Programme Saturday, May 24, 2003<br />

08.30–10.30 Auditorium III<br />

50<br />

Oral Session: Management and Economics<br />

Chairs: H.C. Diener, Germany and P. Rothwell, United Kingdom<br />

08.30–08.40 Complaints and malpractice in stroke care<br />

A. Johansson, A. Staaf, K. Asplund, Department of Public Health and Clinical<br />

Medicine, Sweden<br />

08.40–08.50 The use of MORUCOS (Model of Resource Utilisation, Costs and<br />

Outcomes for Stroke) for the cost-effectiveness analysis and<br />

prioritisation of selected stroke interventions<br />

M. Moodie, R. Carter, C. Mihalopoulos, H. Dewey, B. Chambers,<br />

National Stroke Research Institute, Australia<br />

08.50–09.00 Pre- and in-hospital delays from stroke onset to intra-arterial<br />

thrombolysis<br />

K. Nedeltchev, M. Arnold, C. Brekenfeld, J. Isenegger, L. Remonda, G. Schroth,<br />

H.P. Mattle, University of Bern, Switzerland<br />

09.00–09.10 Is there equal access to longer-term stroke care?<br />

Findings from the South London Stroke Register<br />

C. Coshall, K. Tilling, C. McKevitt, C. Wolfe, King's College London,<br />

United Kingdom<br />

09.10–09.20 Heparin in acute ischemic stroke: study results and clinical reality<br />

M. Daffertshofer, E. Grips, M.G. Hennerici, German Stroke Units, University<br />

Heidelberg, Universitätsklinikum Mannheim, Germany<br />

09.20–09.30 Adequacy of documentation in medical records of stroke patients<br />

B. Norrving, B. Nilsson, K. Wittlöv, M. Sederholm, University Hospital Lund,<br />

Sweden<br />

09.30–09.40 Stroke risk factor management: are there inequalities in treatment?<br />

C. Coshall, K. Tilling, C. McKevitt, C. Wolfe, King's College London,<br />

United Kingdom


09.40–09.50 Risk factor change after cryptogenic stroke in young patients.<br />

The PFO ASA study<br />

C. Arquizan, E. Touzé, M. Zuber, C. Lamy, J.L. Mas, Patent Foramen Ovale and<br />

Atrial Septal An<strong>eu</strong>rysm Study Group, Hospital Sainte Anne, France<br />

09.50–10.00 Comprehensive shared care following stroke; effective secondary<br />

intervention for vascular risk factors and deression in a high-risk<br />

group<br />

J. Joubert, S. Davis, C. Reid, L. Johnsen, D. Ruth, D. Barton,<br />

Royal Melbourne Hospital, Australia<br />

10.00–10.10 Does caregiver training and support in stroke reduce costs of care?<br />

L. Kalra, A. Evans, I. Perez, A. Melbourn, A. Patel, M. Knapp, Guy's,<br />

King's and St Thomas's School of Medicine, King's College London,<br />

United Kingdom<br />

10.10–10.20 The time course of resource use and costs following ischemic stroke<br />

J.J. Caro, K. Migliaccio-Walle, K.J. Ishak, J.A. O'Brien, Caro Research<br />

Institute, USA<br />

10.20–10.30 SAFE II Study: why anticoagulants still remain underused in Europe?<br />

Part 1-A survey from general practitioners and cardiologists<br />

D. Deplanque, D. Leys, L. Parnetti, R. Schmidt, J. de R<strong>eu</strong>ck , J. Ferro, J.L. Mas,<br />

V. Gallai, N<strong>eu</strong>rology and Pharmacology Departments, CHRU Lille, France<br />

51


Scientific Programme Saturday, May 24, 2003<br />

10.30–11.00 Auditorium I<br />

52<br />

Invited Lecture: Current Concepts in Reconstructive<br />

N<strong>eu</strong>robiology<br />

O. Wiestler, Germany<br />

11.00–11.30 Coffee Break<br />

11.30–12.00 Auditorium I<br />

Award Presentations<br />

J. Bogousslavsky, Switzerland


12.00–13.05 Auditorium I<br />

Oral Session: News from Large Clinical Trials<br />

Chairs: J.P. Mohr, USA and N.G. Wahlgren, Sweden<br />

12.00–12.15 Ximelagatran compared with Warfarin for prevention of stroke and<br />

systemic embolism in patients with non-valvular atrial fibrillation:<br />

SPORTIF III<br />

H.C. Diener, SPORTIF III Investigators, University Essen, Germany<br />

12.15–12.30 Effect of estrogen plus progestin on stroke in the Women’s Health<br />

Initiative<br />

A.E. Baird, S. Wassertheil-Smoller, National Institute of<br />

N<strong>eu</strong>rological Disorders and Stroke, USA<br />

12.30–12.40 Abciximab in emergent stroke treatment:<br />

influence of time and other variables on outcome<br />

A. Davalos, Hospital Josep Trueta, Spain<br />

12.40–12.50 Dipyridamole in stroke prevention:<br />

the effect of dipyridamole on blood pressure<br />

E. De Schryver, ESPRIT Study Group, University Medical Center Utrecht,<br />

The Netherlands<br />

12.50–13.05 Initial findings of the rt-PA acute stroke treatment review panel<br />

T.J. Ingall, W.M. O'Fallon, T.A. Louis, V. Hertzberg, L.R. Goldfrank, K. Asplund,<br />

Mayo Clinic Scottsdale, USA<br />

13.05–13.15 Auditorium I<br />

Closure and Announcement of ESC 2004<br />

M.G. Hennerici, Germany<br />

53


Poster Sessions Thursday, May 22, 2003<br />

54<br />

Poster Session I<br />

Chairs: S. Davis, Australia, W. Hacke, Germany and J. Ferro, Portugal<br />

Epidemiology<br />

1 Estimating stroke unit bed numbers for Scotland: the Scottish Borders<br />

Stroke Study Poisson bed-occupancy model<br />

P. Syme, S. Litster, K. McKinnon, Borders General Hospital, University of<br />

Edinburgh, United Kingdom<br />

2 Risk of stroke in patients with atrial fibrillation when anticoagulation<br />

is adjusted for endoscopic procedures during endoscopic procedures<br />

D. Blacker, E. Wijdicks, R. McClelland, Mayo Clinic, USA<br />

3 The prevalence of stroke survivors in rural South Africa: results from<br />

the Southern Africa Stroke Prevention Initiative rural Agincourt field<br />

site<br />

M. Connor, B. Casserly, C. Dobson, M. Thorogood, C. Warlow,<br />

SASPI Project Team, University of the Witwatersrand, South Africa<br />

4 Secondary stroke prophylaxis and health seeking behaviour in stroke<br />

survivors in rural South Africa: report from the SASPI study<br />

M. Connor, M. Thorogood, B. Casserly, C. Dobson, C. Warlow,<br />

SASPI Project Team, University of the Witwatersrand, South Africa<br />

5 Death certification errors in the Scottish Borders Stroke Study (SBSS)<br />

H. Clinkscale, P. Syme, Borders General Hospital, United Kingdom<br />

6 Medium and long-term variability in blood pressure in patients with<br />

cerebrovascular disease: implications for clinical practice and<br />

research<br />

R.L. Cuffe, S.C. Howard, A. Algra, C.P. Warlow, P.M. Rothwell,<br />

Stroke Prevention Research Unit, Department of Clinical N<strong>eu</strong>rology,<br />

University of Oxford, United Kingdom<br />

7 Differences in frequency of risk factors by aetiogical subtype of<br />

ischaemic stroke in population-based studies<br />

U. Schulz, P.M. Rothwell, Stroke Prevention Research Unit,<br />

University Department of Clinical N<strong>eu</strong>rology, United Kingdom


8 Studies of risk factors for different aetiological subtypes of ischaemic<br />

stroke should be population-based<br />

U. Schulz, P.M. Rothwell, Stroke Prevention Research Unit, University<br />

Department of Clinical N<strong>eu</strong>rology, United Kingdom<br />

9 Prevalence of the multiple modifiable risk factors for first ischemic<br />

stroke<br />

D.I. Hadjiev, P.P. Mineva, M.I. Vukov, Medical University, Sofia and Thracian<br />

University, Bulgaria<br />

10 What determines handicap after stroke? The North East Melbourne<br />

Stroke Incidence Study (NEMESIS)<br />

J.W. Sturm, G.A. Donnan, H.M. Dewey, R.A.L. Macdonell, A.K. Gilligan,<br />

A.G. Thrift, National Stroke Research Institute, Australia<br />

11 Should intensive preventive treatment be continued indefinitely after<br />

a transient ischaemic attack?<br />

E. Flossmann, T.G. Clark, M.F. Murphy, P.M. Rothwell, Stroke Prevention<br />

Research Unit, Radcliffe Infirmary, University of Oxford, United Kingdom<br />

12 Older stroke patients in Europe: the forgotten group?<br />

A. Bhalla, R. Grieve, K. Tilling, A. Rudd, C. Wolfe, Public Health Department,<br />

Guy’s, King’s and St Thomas’ School of Medicine, United Kingdom<br />

13 Area-based deprivation is associated with ischaemic stroke risk<br />

factors and readmission due to any vascular event in the Greater<br />

Glasgow Health Board (GGHB) area<br />

S. Aslanyan, C.J. Weir, K.R. Lees, Division of Cardiovascular and Medical<br />

Sciences, University of Glasgow, United Kingdom<br />

14 Worldwide comparison of age-standardised stroke incidence with<br />

true age-adjusted stroke risk<br />

P. Syme, A. Byrne, R. Chen, Borders General Hospital, University of Edinburgh,<br />

United Kingdom<br />

15 Not all stroke patients who present to hospital are admitted.<br />

How do these cases differ from admitted cases? Results from<br />

North East Melbourne Stroke Incidence Study (NEMESIS)<br />

A.K. Gilligan, J.W. Sturm, H.M. Dewey, G.A. Donnan, R.A. Macdonell,<br />

A.G. Thrift, National Stroke Research Institute, Australia<br />

55


Poster Sessions Thursday, May 22, 2003<br />

56<br />

16 Prevalence of self-reported stroke among older Singapore Asians –<br />

an inter-racial comparison<br />

N. Venketasubramanian, S.M. Saw, C.Y. Hong, L. Tan, S. Sahadevan, J.J. Chin,<br />

E.S. Krishnamoorthy, V. Ramachandran, National N<strong>eu</strong>roscience Institute,<br />

Singapore<br />

17 Inhospital delays in patients with acute stroke<br />

G.J. Jungehülsing, C.H. Nolte, K. Rossnagel, S. Roll, J. Müller-Nordhorn,<br />

A. Reich, S.N. Willich, K.M. Einhäupl, A. Villringer, Charité Berlin, Germany<br />

18 Declining incidence and mortality of stroke in persons<br />

25 to 74 years in Finland<br />

J. Sivenius, P. Immonen-Räihä, A. Lehtonen, C. Sarti, J. Torppa, J. Tuomilehto,<br />

V. Salomaa, University of Kuopio, Finland<br />

19 Ischaemic stroke outcomes by aetiological (TOAST) subtypes<br />

R. McGovern, C. Hajat, M. Patel, A. Rudd, C. Wolfe, Department of Public<br />

Health Sciences, King's College London, United Kingdom<br />

20 Aetiological subtypes of strokes: the relationship between the index<br />

stroke subtype and recurrence stroke subtype<br />

R. McGovern, C. Hajat, A. Rudd, C. Wolfe, Department of Public Health<br />

Sciences, King's College London, United Kingdom<br />

21 Survival after urinary catheterisation in the wirral stroke B&B cohort<br />

study<br />

J.A. Barrett, H. Pandya, V. Little, P. Weir, M.E. Barrett, R. Plant, M. Pritchard<br />

Howarth, G. Sangster, C. Jack, C.L. Watkins, Wirral Stroke Service,<br />

United Kingdom<br />

22 Predictors of in-hospital mortality in acute stroke in very old people<br />

C. Tejero, E. Mostacero, J.A. Mauri, L.F. Pascual, L.J. Lopez del Val, S. Santos,<br />

Unidad de ictus, Servicio de N<strong>eu</strong>rología, Hospital Clínico Zaragoza, Spain


23 Air pollution and cerebrovascular disease<br />

M.L. Cuadrado, J.M. San Román, C. Guijarro, M.I. González-Anglada,<br />

J.L. Dobato, Ciencias de la Salud, Universidad Rey Juan Carlos,<br />

Fundación Hospital Alcorcón, Spain<br />

Diagnosis and Treatment with Ultrasound<br />

1 Parameters of cerebral perfusion in bilateral contrast harmonic<br />

imaging with second generation contrast specific agents<br />

J. Eyding, W. Wilkening, C. Krogias, S. Meves, T. Postert, St. Josef Hospital,<br />

Ruhr University Bochum, Germany<br />

2 Assessment of brain perfusion by ultrasound in a one-vessel<br />

occlusion model in rats<br />

M. Fatar, K. Tiemann, M. Stroick, B. Luederitz, M.G. Hennerici, S. Meairs,<br />

Dept. of N<strong>eu</strong>rology, Klinikum Mannheim, University of Heidelberg, Germany<br />

3 Contrast diminution imaging of the human brain – first experience on<br />

healthy volunteers and acute stroke patients<br />

K. Meyer, J. Lahmann, G. Seidel, Universitätsklinikum Schleswig-Holstein,<br />

Campus Lübeck, Klinik für N<strong>eu</strong>rologie, Germany<br />

4 Is there a relationship among carotid stenosis, symptoms and<br />

cerebrovascular reactivity (CVR) evaluated by transcranial Doppler<br />

with Diamox test?<br />

V.F. Zetola, A.R. Massaro, L.C. Werneck, E.M. Novak, M. Scaff,<br />

Universidade Federal do Parana, Brazil<br />

5 Ischemic stroke in young adults. Is n<strong>eu</strong>rosonology associated to the<br />

prevalence of classical atherosclerosis factors?<br />

M.J. Moltó-Jordà, M. Alvarez-Sauco, A. Pampliega-Pérez, J. Carneado-Ruiz,<br />

R. Hernández-Lorido, F. Gracia-Fleta, S. Bustos-Terol, Hospital General<br />

Universitari d'Alacant, Spain<br />

6 Enhancement of enzymatic fibrinolysis with ultrasound and<br />

microbubbles<br />

P. Cintas, F. Nguyen, B. Bon<strong>eu</strong>, V. Larrue, University of Toulouse, France<br />

57


Poster Sessions Thursday, May 22, 2003<br />

58<br />

7 Ultrasound perfusion imaging in acute middle cerebral artery<br />

infarction<br />

G. Seidel, K. Meyer, G. Berdien, J. Lahmann, University Hospital<br />

Schleswig-Holstein, Campus Lübeck, Germany<br />

8 Reduced frequency of embolic signals in severe symptomatic carotid<br />

stenosis with poststenotic arterial narrowing and/or flow velocity<br />

reduction<br />

T. Blaser, S. Guhr, H. Lotze, C.W. Wallesch, M. Goertler, Otto-von-Guericke<br />

University Magdeburg, Germany<br />

9 “To see or not to see”: a prospective study comparing transcranial<br />

color coded duplex sonography to transcranial Doppler in stroke<br />

patients<br />

F. Perren, R. Kern, R. Prager, M.G. Hennerici, S. Meairs,<br />

Universitätsklinikum Mannheim, University of Heidelberg, Germany<br />

10 A rapid non-invasive method to visualise ruptured an<strong>eu</strong>rysms in the<br />

emergency room: three-dimensional unenhanced power Doppler<br />

imaging<br />

F. Perren, J. Gaa, P. Horn, P. Schmiedek, M.G. Hennerici, S. Meairs,<br />

Universitätsklinikum Mannheim, Germany<br />

11 Interobserver agreement of frequency and velocity parameters<br />

assessed by Doppler/duplex sonography in patients with<br />

> 50 % internal carotid stenosis<br />

S.G. Guhr, T.B. Blaser, S.K. Krueger, C.W.W. Wallesch, M.G. Goertler,<br />

Universitiy of Magdeburg, Germany<br />

12 Interobserver agreement for diameter measurements on colour-coded<br />

duplex images in patients with > 50 % internal carotid stenosis<br />

S. Guhr, T. Blaser, C.W. Wallesch, M. Goertler, Universitiy of Magdeburg,<br />

Germany<br />

13 Hematologic factors and transcranial Doppler velocities<br />

C. Togay-Isikay, N. Uzuner, D. Gücüyener, G. Özdemir,<br />

Osmangazi University, School of Medicine, Turkey


14 Relevance of hemodynamc impairment to brain lesion in<br />

asymptomatic carotid stenosis (ACAS): transcranial Doppler (TCD)<br />

magnetic resonance angiography (MRA) correlation<br />

Y. Lee, D. Kim, J. Min, S. Park, Seoul Municipal Boramae Hospital and<br />

Seoul National University, South Korea<br />

15 Measurement of carotid stenosis: comparisons between duplex and<br />

angiogram, and endarterectomy specimen<br />

L.J.H. Lee, Department of N<strong>eu</strong>rology, National Health Insurance Corporation<br />

Ilsan Hospital, South Korea<br />

16 Transcranial Doppler measurements in parenchymal hemorrhage<br />

L. Csiba, G. Settakis, D. Bereczki, P. Bagyi, J. Kollar, B. Fulesdi,<br />

University of Debrecen, Medical and Health Science Center, Hungary<br />

Acute Stroke – Symptoms and Clinical Diagnosis<br />

1 Cognitive and behavioural aspects affecting early referral of acute<br />

stroke patients; stroke related self-care responses<br />

K. Makinde, M. Shah, D. Schelewa, P. Thomas, Prince Philip Hospital,<br />

United Kingdom<br />

2 Different patterns of silent infarcts and early ischemic changes in<br />

acute stroke patients<br />

F. Corea, N. Tambasco, R. Luccioli, E. Ciorba, L. Parnetti, V. Gallai,<br />

University of Perugia, Italy<br />

3 Anterior cerebral artery involvement:<br />

early CT-scan changes in stroke patients<br />

N. Tambasco, F. Corea, R. Luccioli, V. Bocola, G.P. Pelliccioli, L. Parnetti,<br />

V. Gallai, University of Perugia, Italy<br />

4 Reliability of estimating Scandinavian stroke scale scores from<br />

hospital admission records<br />

M. Barber, M. Fail, M. Shields, D.J. Stott, P. Langhorne, Academic Section of<br />

Geriatric Medicine, Glasgow Royal Infirmary, United Kingdom<br />

59


Poster Sessions Thursday, May 22, 2003<br />

60<br />

5 Should non-n<strong>eu</strong>rologists see TIA patients?<br />

S.S.M. Razvi, P. Crawford, I. Bone, K.W. Muir, Southern General Hospital,<br />

Glasgow, United Kingdom<br />

6 Intravenous MAGnesium Efficacy for Stroke (IMAGES) Trial –<br />

baseline data and trial power<br />

K.R. Lees, IMAGES Study Group, University of Glasgow, United Kingdom<br />

7 Usefulness of the OCSP classification in the assessment of cerebral<br />

ischemia in a population-based study<br />

F. De Santis, C. Marini, S. Sacco, T. Russo, R. Della Cagna, A. Carolei,<br />

University of L'Aquila, Italy<br />

8 Clinical features of suspected acute stroke patients referred to an<br />

emergency room<br />

A. Mohd Nor, S.J. Louw, A.G. Dyker, M. Davis, B. Sen, G.A. Ford, The Freeman<br />

Hospital and University of Newcastle upon Tyne, United Kingdom<br />

9 Inter-observer agreement between paramedic recorded n<strong>eu</strong>rological<br />

signs with face arm speech test and physician assessment in acute<br />

stroke/TIA referrals<br />

A. Mohd Nor, J. Davis, S.J. Louw, C. McAllister, A.G. Dyker, M. Davis, B. Sen,<br />

D. Jenkinson, G.A. Ford, The Freeman Hospital and University of Newcastle<br />

upon Tyne, United Kingdom<br />

10 Central, anteromedial and posterolateral infarcts of thalamus:<br />

three new types<br />

E. Carrera, P. Michel, J. Bogousslavsky, University Hospital Lausanne,<br />

Switzerland<br />

11 Is OSCP a valid indicator for ischemic stroke localisation and<br />

outcome compared to CT scan?<br />

V. Caso, P. Paciaroni, G. Silvestrelli, F. Corea, M. Venti, P. Milia, R. Scaroni,<br />

L. Parnetti, V. Gallai, Perugia General Hospital, Italy<br />

12 Bilateral paramedian thalamic infarction due to infarction of the<br />

artery of percheron: a case report<br />

D. Sajeel, D. Heaney, P. Gompertz, Barts and the London Hospital,<br />

United Kingdom


13 Intractable hiccup in acute ischemic stroke<br />

K.M. Yoo, B.G. Yoo, K. Kim, J.K. Cha, Kosin University College of Medicine,<br />

South Korea<br />

AS Monitoring and Complications – Stroke Units<br />

1 Effect of age on access to stroke care in England, Wales and Northern<br />

Ireland: results from the National Sentinel Audits of Stroke 1998–2002<br />

A.G. Rudd, D. Lowe, A. Hoffman, P. Irwin, M. Pearson, Royal College of<br />

Physicians London, United Kingdom<br />

2 Is the gag reflex useful in management of acute stroke?<br />

D.J. Ramsey, D.G. Smithard, N. Donaldson, L. Kalra, Guy's,<br />

King's & St Thomas' School of Medicine, United Kingdom<br />

3 Morphological changes in the brain of rats in acute period of<br />

experimental hemorragic stroke<br />

A.N. Makarenko, R. Poznyakov, M. Evzelman, A. Kultcikov,<br />

I. Vasilyeva, General Pathology Department, Oryol State University,<br />

Russian Federation<br />

4 Blood gases early after stroke<br />

C. Roffe, S. Sills, School of Medicine, Keele University, United Kingdom<br />

5 How to save 24 minutes in thrombolysis for acute ischemic stroke<br />

J. Martí-Fàbregas, D. Cocho, R. Belvís, A. Al<strong>eu</strong>, X. Pagonabarraga,<br />

M.D. García, B. Marín, L. Molina, J. Díaz, J.L. Martí-Vilalta, Hospital de la<br />

Santa Cr<strong>eu</strong> i Sant Pau, Spain<br />

6 The incidence of deep venous thrombosis detected by Doppler<br />

ultrasound in hemiplegic Asian stroke patients is comparable to<br />

western stroke populations<br />

A. Sim, H.H. The, C.F. Chan, H.B. Pey, H.M.M. Chang, M.K. Teoh, I. Husein,<br />

P. Lim, C. Chen, National N<strong>eu</strong>roscience Institute, Singapore General Hospital<br />

Campus, Singapore<br />

61


Poster Sessions Thursday, May 22, 2003<br />

62<br />

7 Comparison of MMP-2 and MMP-9 kinetics in stroke and lacunar<br />

stroke<br />

M. Stroick, M. Fatar, E. Senn, S. Kuehl, M.G. Hennerici, Dept. of N<strong>eu</strong>rology,<br />

Klinikum Mannheim, University Heidelberg, Germany<br />

8 Cerebrovascular risk factors and lacunar stroke outcome.<br />

Have they some influence?<br />

V. Mejías, E. Díez-Tejedor, B. Fuentes, S. Monteagudo, J. Gracia, S. <strong>Esc</strong>alante,<br />

J. Gracia San Román, University Hospital La Paz, Spain<br />

9 Perfusion CT for the prediction of large hemispheric infarctions in<br />

patients with hyperacute stroke<br />

E.M. Nam, S.P. Kloska, F. Stögbauer, E. Klotz, W. Heindel, E.B. Ringelstein,<br />

D.G. Nabavi, University of Münster, Germany<br />

10 Nocturnal oxygen saturation in patients with acute stroke:<br />

does it change over the first three nights of admission to hospital<br />

C. Roffe, S. Sills, The Medical School, Keele University, United Kingdom<br />

11 Depression following a stroke: how good are clinicians at detecting<br />

and treating it?<br />

E. Lightbody, L. Daniels, H. Dickinson, M. Jack, M. Leathley, M. van den Broek,<br />

C. Watkins, University of Central Lancashire, United Kingdom<br />

12 Stroke prevention and management in primary care in the UK<br />

E. Lightbody, I. Benett, H. Hosker, M. Leathley, C. Watkins,<br />

University of Central Lancashire, United Kingdom<br />

13 Thrombolysis for acute ischaemic stroke: are we ready in the UK?<br />

I.M. Shah, C.H. McAlpine, D.J. Stott, University of Glasgow, United Kingdom<br />

14 Infectious serious adverse events (iSAE) are independently<br />

associated with poor outcome after acute ischaemic stroke<br />

S. Aslanyan, C.J. Weir, H.C. Diener, M. Kaste, K.R. Lees, Division of<br />

Cardiovascular and Medical Sciences, University of Glasgow, United Kingdom<br />

15 Feeding stroke patients: a survey of current practice in UK hospitals<br />

M.S. Dennis, G. Cranswick, R. Flaig, S. Lewis, C. McLaverty, C. Williams,<br />

International Stroke Trials (IST) Collaboration – FOOD, University of Edinburgh,<br />

United Kingdom


16 Stroke units and mixed stroke services in seven Italian regions:<br />

the PROSIT study<br />

L. Candelise, G. Micieli, R. Sterzi, PROSIT, IRCCS Ospedale Maggiore<br />

Policlinico, Italy<br />

17 Hypoxia and abnormal breathing patterns in hyperacute stroke<br />

A. Rowat, J. Wardlaw, M. Dennis, R. Lindley, P. Andrews,<br />

University of Edinburgh, United Kingdom<br />

18 Stroke units in real life compared to research units. Results from the<br />

National Audit England, Wales and Northern Ireland<br />

A. Hoffman, D. Lowe, P. Irwin, M. Pearson, A. Rudd, Royal College of<br />

Physicians, United Kingdom<br />

19 Can a stroke care monitoring unit improve the results of a<br />

conventional stroke unit?<br />

F. Nombela, R. González-Santiago, M. Tamayo, J. Vivancos,<br />

Hospital Universitario De La Princesa, Spain<br />

20 Utility of serum GFAP in monitoring acute MCA territorial infarction<br />

C. Foerch, O. Singer, T. N<strong>eu</strong>mann-Haefelin, A. Raabe, M. Sitzer,<br />

J.W. Goethe University, Germany<br />

21 Admission characteristics, intensity of care and outcome at the<br />

Debrecen Stroke Unit at the turn of the millennium<br />

D. Bereczki, I. Fekete, B. Fülesdi, A. Valikovics, K. Fekete, L. Csiba,<br />

University of Debrecen, Hungary<br />

22 Cerebral (middle cerebral artery blood velocity, pulsatility index) and<br />

systemic (blood/pulse pressure, cardiac output, augmentation index)<br />

haemodynamics during acute stroke<br />

P. Rashid, J. Leonardi-Bee, B. Whysall, P.M. Bath, University of Nottingham,<br />

United Kingdom<br />

23 What are the consequences of urinary catheterisation in patients<br />

with acute stroke?<br />

J. Kwan, P. Hand, M. Dennis, P. Sandercock, Western General Hospital,<br />

University of Edinburgh, United Kingdom<br />

63


Poster Sessions Thursday, May 22, 2003<br />

64<br />

24 Association between blood pressure values and edema formation in<br />

patients with acute stroke<br />

G. Tsivgoulis, A. Synetos, K. Spengos, V. Kotsis, E. Manios,<br />

P. Konstantopoulou, K. Vemmos, University of Athens, Medical School, Greece<br />

25 Acute prolonged corrected QT interval is related to severe stroke<br />

A.H. Christensen, A.F. Christensen, G. Boysen, Bispebjerg Hospital, Denmark<br />

Acute Stroke – Treatment Concepts<br />

1 Thrombolysis for stroke in elderly patients<br />

C. Vatankhah, M. Seidl, P. Erban, S. Sauerbruch, M. Dittmar, W. Jakob,<br />

G. Ickenstein, M. Horn, University of Regensburg, Germany<br />

2 Stroke network with regional stroke care units and high speed<br />

telemedicine in Germany. The Telemedic Pilot Project of an<br />

Integrative Stroke Care (TEMPIS) in Eastern Bavaria<br />

J. Schenkel, M.L.J. Wimmer, M. Horn, H.J. Audebert, Städtisches<br />

Krankenhaus München-Harlaching, Germany<br />

3 Variation in use of antiplatelet therapy after stroke<br />

S.C. Smith, Geratology Department, Radcliffe Infirmary, United Kingdom<br />

4 Reduced the P-selectin expression on platelets and C-reactive<br />

protein after statin therapy in chronic atherosclerotic ischemic stroke<br />

J.K. Cha, K.M. Yoo, College of Medicine, Dong-A University, South Korea<br />

5 Changes of the P-selectin expression on platelets and plasma<br />

concentration of C-reactive protein in acute atherosclerotic infarction<br />

treated with the loading dose of clopidogrel<br />

W.J. Kim, J.K. Cha, College of Medicine, Dong-A University, South Korea<br />

6 Getting started: using guidelines to develop a better stroke service<br />

S. Smith, S. Manchanda, L. Gladman, O. Drew, Wycombe Hospital,<br />

United Kingdom<br />

7 Factors influencing the pre- and in-hospital management of acute<br />

stroke – data from a Greek tertiary care hospital<br />

J. Rudolf, E. Koutlas, G. Grivas, X. Fitsioris, G. Georgiadis,<br />

Papageorgiou Regional General Hospital, Greece


8 Early hyperglycaemia is important in ischaemic stroke evolution<br />

T.A. Baird, M.W. Parsons, K.S. Butcher, P.G. Colman, P.M. Desmond,<br />

B.M. Tress, B. Chambers, T. Phanh, S.M. Davis, Royal Melbourne Hospital,<br />

Australia<br />

9 Efficacy of dual anti-platelet therapy in cerebrovascular disease as<br />

demonstrated by decline in microembolic signals<br />

R. Esagunde, M.P. Lee, H.Y. Gan, K.S. Wong, H.M.M. Chang, C. Chen,<br />

M.C. Wong, National N<strong>eu</strong>roscience Institute, Singapore General Hospital<br />

Campus, Singapore<br />

10 Delayed occlusion after internal carotid artery dissection under<br />

unfractionated heparin<br />

J.P. Dreier, F. Lürtzing, M. Kappmeier, G. Bohner, R. Klingebiel, S. Leistner,<br />

K.M. Einhäupl, E. Schielke, J.M. Valdueza, N<strong>eu</strong>rology, Charité,<br />

Humboldt University, Germany<br />

11 Sources of delay to thrombolysis among acute stroke patients who<br />

arrive at the emergency room soon after symptom onset<br />

J.G. Merino, N. Simpson, S. Silliman, B. Quinn, S. Erenguc,<br />

University of Florida, College of Medicine, USA<br />

12 Acute stroke treatment with systemic thrombolysis in the clinical<br />

practice of a single centre<br />

A. Hartmann, M. Marx, H.C. Koennecke, University Hospital Benjamin<br />

Franklin, Free University Berlin, Germany<br />

13 Physical inactivity in acute stroke units: is a new model of care required?<br />

A.J. Bernhardt, A. Thrift, H. Dewey, G. Donnan, National Stroke Research<br />

Institute, Australia<br />

14 Drug induced hypothermia reduces ischemic damage:<br />

effects of the cannabinoid HU-210<br />

H. Ovadia, N. Gai, R. Mechoulam, J. Weidenfeld, R.R. Leker,<br />

Agnes Ginges Center for Human N<strong>eu</strong>rogenetics, Hadassah Hospital, Israel<br />

65


Poster Sessions Thursday, May 22, 2003<br />

66<br />

15 Anticoagulation therapy in stroke patients treated with intravenous<br />

thrombolysis<br />

A.R. Mikulik, M. Dufek, D. Goldemund, M. Reif, Cerebrovascular Center,<br />

Masaryk University, St. Anne's Hospital, Czech Republic<br />

16 Emergency carotid stenting for hyperacute or acute ischemic stroke<br />

patients<br />

T. Mori, K. Imai, M. Watanabe, H. Izumoto, T. Kamiya, Shonan Kamakura<br />

General Hospital, Japan<br />

17 Short-term clinical outcome after cerebral balloon angioplasty or<br />

stenting for vertebro-basilar artery occlusive lesions in acute stroke<br />

patients<br />

T. Mori, K. Imai, H. Izumoto, M. Watanabe, T. Kamiya, Shonan Kamakura<br />

General Hospital, Japan<br />

18 Why are patients admitted within 2 hours not given thrombolysis?<br />

D. Cocho, R. Belvís, J. Martí-Fàbregas, A. Al<strong>eu</strong>-Bonaut, X. Pagonabarraga,<br />

D. García, B. Marín, J.L. Martí-Vilalta, Hospital de la Santa Cr<strong>eu</strong> i Sant Pau,<br />

Spain<br />

19 The effect of losartan on global and focal cerebral perfusion and<br />

renal function in hypertensives in early ischaemic stroke<br />

F.S. Nazir, J.R. Overell, T.E. Hilditch, K.R. Lees, University of Glasgow,<br />

United Kingdom<br />

20 Opportunities for secondary preventative pharmacotherapy at a<br />

hospital-based TIA clinic<br />

S.S.M. Razvi, P. Crawford, I. Bone, K.W. Muir, Southern General Hospital,<br />

United Kingdom<br />

21 Predictors of angiographic recanalisation and clinical improvement<br />

in patients with middle cerebral artery territory infarction treated by<br />

thrombolytics<br />

J.H. Kwon, S.U. Kwon, C.G. Choi, J.S. Kim, Ulsan University College of<br />

Medicine, Asan Medical Center, South Korea


22 Intravenous thrombolysis in acute ischemic stroke:<br />

a single centre Latin American experience<br />

A. Hoppe, P. Lavados, A. Brunser, D. Cárcamo, R. Vedugo, M. Campero,<br />

J. Barahona, V. Diaz, I. Gonzalez, F. Vergara, Clínica Alemana de Santiago, Chile<br />

23 The anti-inflammatory effects of aggrenox: decreased gene<br />

expression in platelet-monocyte aggregates<br />

A.A.S. Weyrich, B.J.R. Eyre, C.G.A. Zimmerman, D.S.M. Prescott,<br />

University of Utah, USA<br />

24 N<strong>eu</strong>rological deterioration following early improvement in<br />

intravenous rt-PA therapy. Possible underlying mechanisms<br />

A. Dae-il Chang, K.C. Chung, College of Medicine, Kyung Hee University,<br />

South Korea<br />

25 Do we need new evidence? Planning a trial from overview data<br />

M.G. Celani, S. Ricci, E. Righetti, L. Convito, Stroke Service USL 2 Perugia,<br />

Italy<br />

26 Early or late treatment of symptomatic internal carotid artery stenosis<br />

with stent protected angioplasty?<br />

U. Becker, T. Goldhagen, A. Mueller, D. Mucha, H. Reichmann, R. von Kummer,<br />

University of Dresden, Germany<br />

27 Recurrence of vascular events in patients with ischemic stroke/TIA<br />

and atrial fibrillation with respect to different treatment strategies in<br />

secondary prevention<br />

S. Tentschert, S. Parigger, V. Dorda, K. Bittner, S. Greisenegger, W. Lang,<br />

W. Lalouschek, University Hospital of Vienna, Austria<br />

28 Endovascular treatment of acute ischemic stroke related to acute<br />

carotid artery dissection and occlusion<br />

S.H. Kim, A.M. Siddiqui, A.I. Qureshi, E.I. Levy, R.A. Hanel, M.R. Harrigan,<br />

J.U. Howington, A.R. Xavier, J.F. Kirmani, L.N. Hopkins,<br />

Department of N<strong>eu</strong>rosurgery, Millard Fillmore Hospital,<br />

State University of New York at Buffalo, USA<br />

67


Poster Sessions Thursday, May 22, 2003<br />

68<br />

29 Anticoagulation vs aspirin in the treatment of acute spontaneous<br />

cervical artery dissections<br />

A.A. Arauz, C. Espinoza, L. Murillo, C. Cantú, F. Barinagarrementeria,<br />

National Institute of N<strong>eu</strong>rology (Mexico), Spain<br />

Stroke Outcome<br />

1 Are asymptomatic intracranial hemorrhages really innocuous?<br />

D.M. Kent, L. Price, H.P. Selker, Division of Clinical Care Research,<br />

Tufts-New England Medical Center, USA<br />

2 Clinical outcome after thrombolysis in patients with internal carotid<br />

artery occlusion<br />

M. Zaletel, V. Svigelj, B. Zvan, N<strong>eu</strong>rology Clinic, University Medical Center<br />

Ljubljana, Slovenia<br />

3 Changes in body weight at 3 months after stroke<br />

A.C. Jonsson, I. Lindgren, B. Hallstrom, B. Norrving, A. Lindgren,<br />

Department of Clinical N<strong>eu</strong>roscience, Universtity Hospital Lund, Sweden<br />

4 Cerebrovascular risk factors and antithrombotic treatment on brain<br />

infarct haemorrhagic transformation<br />

S. Monteagudo, B. Fuentes, E. Díez Tejedor, J. Gracia, V. Mejías, S. <strong>Esc</strong>alante,<br />

University Hospital La Paz, Spain<br />

5 Cerebrovascular risk factors and non lacunar ischemic stroke<br />

outcome<br />

R. Merino, E. Díez Tejedor, B. Fuentes, S. Monteagudo, J. Gracia, V. Mejías,<br />

S. <strong>Esc</strong>alante, University Hospital La Paz, Spain<br />

6 Could previous treatment with statins have benefits in non lacunar<br />

ischemic stroke outcome?<br />

R. Merino, E. Díez Tejedor, B. Fuentes, J. Gracia, V. Mejías,<br />

S. Monteagudo, S. <strong>Esc</strong>alante, University Hospital La Paz, Spain<br />

7 Correlation of size and location of hematoma with prognosis in<br />

intracerebral hemorrhage patients<br />

K. Khosravi, J. Lotfi, S. Nafisi, N. Sedighi, Shariati Hospital, Iran


8 Use of CT in place of MR-DWI in the three-item scale for the early<br />

prediction of stroke recovery<br />

V. Wright, R. Horvath, J. Chalela, J. Dambrossio, H. Yu, A. Sharma, D.W. Kang,<br />

M. Ezzeddine, S. Warach, A.E. Baird, National Institute of Health,<br />

National Institute of N<strong>eu</strong>rological Disorders and Stroke, USA<br />

9 The effect of stroke on carer quality of life<br />

D. Sulch, I. Perez, M. Melbourn, L. Kalra, GKT School of Medicine,<br />

United Kingdom<br />

10 The effect of time on the accuracy of stroke prognosis<br />

M. Leathley, A. Sharma, C. Sutton, C. Watkins, University of Central<br />

Lancashire, United Kingdom<br />

11 Intravenous rtPA in 169 acute ischemic stroke patients – safety and<br />

efficacy in clinical routine use over a 4-year time period<br />

O. Mielke, M. Fritzinger, M. Daffertshofer, M.G. Hennerici,<br />

University Hospital Mannheim, Germany<br />

12 Anxiety disorders after minor strokes<br />

L. Bruggimann, J.M.M. Annoni, F. Staub, S. Gramigna, J. Bogousslavsky,<br />

Lausanne University Hospital, Switzerland<br />

13 Early asymptomatic recurrence of cervical artery dissection: 3 cases<br />

E. Touzé, M. Zuber, C. Oppenheim, E. Méary, J.F. Meder, J.L. Mas,<br />

Hôpital Sainte-Anne, France<br />

14 First month prognosis in hypertensive intracerebral hemorrhage<br />

correlated with the adapted Hemphill-Bonovich score<br />

S. Tuta, B. Dumitriu, A. Nistorescu, C. Popa, Institute of Cerebrovascular<br />

Diseases Bucharest, Romania<br />

15 Spontaneous intracranial haemorrhage; which patients need<br />

diagnostic cerebral angiography; comparative study between plain<br />

computed tomography and cerebral angiography in HUSM<br />

J. Abdullah, I. Abu Bakar, I.L. Shuaib, N.N. Naing, Hospital University Sains,<br />

Malaysia<br />

69


Poster Sessions Thursday, May 22, 2003<br />

70<br />

16 Three types of blood glucose level during acute ischemic stroke as<br />

a predictor of early clinical improvement; which one is best?<br />

J. Koo, B. Kim, O. Kwon, S. Kim, H. Bae, Eulji General Hospital,<br />

Eulji University School of Medicine<br />

17 One year follow-up of pharmacoeconomic and clinical<br />

outcomes of hospitalised stroke patients in Hamilton, Canada<br />

A.S.E. Salama, R. Goeree, R. Petrovic, G. Blackhouse,<br />

Hamilton Health Sciences, Canada<br />

18 Primary intracebebral haemorrhage: all Asian study<br />

N. Poungvarin, Siriraj Hospital, Thailand<br />

19 Cross-cultural comparisons of mild cognitive impairment. Impact and<br />

risk factors of dementia and mild cognitive impairment in China and<br />

USA were compaired<br />

G. Xu, J.S. Meyer, Y. Huang, D. Liu, M. Chowdhury, M. Quach, Xijing Hospital,<br />

China<br />

20 Classification of outcome events in a cerebrovascular trial:<br />

prognostic value<br />

D.R. Jovanovic, A. Algra, J. van Gijn, University Medical Center Utrecht,<br />

The Netherlands<br />

21 Evaluation of a stroke scale record form for the combined assessment<br />

of NIH, European and Scandinavian Stroke Scale<br />

M. Goertler, G. Partscht, M. Wunderlich, U. Walter, C.W. Wallesch,<br />

University and Municipal Hospital of Magdeburg, Germany<br />

22 Apolipoprotein E (ApoE) genotypes and outcome in men and women<br />

patients with cerebral ischemia<br />

M. Baranska, G. Gromadzka, A. Ciesielska, I. Szarzynska-Dlugosz, T. Mendel,<br />

A. Czlonkowska, Department of N<strong>eu</strong>rology, Institute of Psychiatry and<br />

N<strong>eu</strong>rology, Poland<br />

23 Mannitol use in acute stroke and case fatality at 30 days:<br />

an observational study<br />

D. Bereczki, S. Szatmári, L. Mihálka, K. Fekete, V. Smolanka, I. Pascu,<br />

I. Fekete, B. Fülesdi, L. Csiba, University of Debrecen, Hungary


24 Influence of stress-realising n<strong>eu</strong>roimmunoendocrine system on the<br />

course and outcome of acute ischemic stroke<br />

V.I. Skvortsova, I.A. Platonova, E.I. Arsenyeva, I.A. Grivennikov,<br />

Russian State Medical University, Russian Federation<br />

25 Ratio of pro-to anti-inflammatory cytokines at admission predicts<br />

infarct volume and n<strong>eu</strong>rological outcome in ischemic stroke<br />

P. Irimia, E. Martínez-Vila, J. Gállego, J. Castillo,<br />

Clínica Universitaria de Navarra, Spain<br />

26 Serum levels of cytokines and adhesion molecules in the acute phase<br />

of ischemic stroke predicts infarct volume but not clinical outcome<br />

P. Irimia, E. Martínez-Vila, J. Gállego, J. Castillo, Clínica Universitaria,<br />

Universidad de Navarra, Spain<br />

27 Outcome in stroke patients with severe dysphagia<br />

G.W. Ickenstein, M. Horn, N. Rallis, R. Goldstein, U. Bogdahn, J. Stein,<br />

University of Regensburg, Germany<br />

28 Association between stroke severity on admission and glycosylated<br />

hemoglobin (HbA1C)<br />

M. Bosnar-Puretic, M. Stojic, V. Vargek-Solter, V. Supanc, V. Demarin,<br />

Sestre Milosrdnice University Hospital, Croatia<br />

29 “Stroke care continuum” – does it influence the outcome after acute<br />

stroke unit treatment?<br />

A. Wiborg, B. Widder, Bezirkskrankenhaus, Department of N<strong>eu</strong>rology and<br />

N<strong>eu</strong>rological Rehabilitation, Germany<br />

30 Prediction of the recovery pattern of auditory comprehension in acute<br />

ischemic stroke using perfusion-weighted CT<br />

K.H. Lee, G.M. Kim, H.H. Kim, S.J. Lee, Y.B. Kim, M.K. Seo, D.L. Na,<br />

C.S. Chung, Samsung Medical Center, Sungkyunkwan University School of<br />

Medicine, South Korea<br />

31 Brainstem infarcton: topography, etiopathogenesis and outcome<br />

E. Vassiliadi, G. Tsivgoulis, K. Spengos, P. Konstantopoulou,<br />

E. Manios, K. Vemmos, University of Athens, Medical School, Greece<br />

71


Poster Sessions Thursday, May 22, 2003<br />

72<br />

32 Prevalence of diabetes mellitus and association with long-term<br />

survival in stroke patients<br />

P. Konstantopoulou, G. Tsivgoulis, K. Spengos, E. Manios, E. Vassiliadi,<br />

V. Kotsis, K. Vemmos, University of Athens, Medical School, Greece<br />

33 Serum cardiac troponin I in acute stroke is related to s-cortisol and<br />

TNF-a<br />

A.H. Christensen, A.F. Christensen, G. Boysen, Bispebjerg Hospital, Denmark<br />

Clinical N<strong>eu</strong>rophysiology<br />

1 What is the angiographic cerebral circulation time?<br />

S. Yamamoto, M. Watanabe, T. Uematsu, K. Takazawa, M. Nukata,<br />

N. Kinoshita, Osaka-Minami National Hospital, Japan<br />

2 Vestibular dysfunctions in anterior inferior cerebellar artery<br />

infarction<br />

H. Lee, H.A. Yi, J. Lee, Y.W. Cho, J.G. Lim, S.D. Yi, Keimyung University<br />

School of Medicine, Dongsan Medical Center, South Korea<br />

3 The control of expiratory muscle function in stroke patients<br />

F. Harraf, W.D. Man, J.F. Rafferty, M.I. Polkey, J. Moxham, L. Kalra, Guy's,<br />

King's & St Thomas' School of Medicine, King's College London,<br />

United Kingdom<br />

4 N<strong>eu</strong>ropsychological findings in asymptomatic carotid artery stenosis<br />

M.D. Mijajlovic, E. Stefanova, N. Sternic, A. Pavlovic, J. Zidverc Trajkovic,<br />

Z. Jovanovic, D.J. Radak, L.J. Ziropadja, V.S. Kostic, Institute of N<strong>eu</strong>rology,<br />

Clinical Center of Serbia, Yugoslavia<br />

Dementia/Higher Cognitive Dysfunction<br />

1 Disability assessment for dementia scale detects mild functional<br />

decline in l<strong>eu</strong>koaraiosis patients. The LADIS (L<strong>eu</strong>koaraiosis and<br />

DISability) Project<br />

A.M. Basile, L. Pantoni, M. Simoni, G. Pracucci, T. Erkinjuntti, G. Waldemar,<br />

J. Bogousslavsky, D. Inzitari, LADIS Study Group, University of Florence, Italy


2 The cognitive impact of carotid endarterectomy:<br />

benefit and for whom?<br />

C. Greber, T. Karapanayiotides, P. Ruchat, V. Kemeny, B. Piechowski-Jozwiak,<br />

P.A. Despland, J. Bogousslavsky, G. Devuyst, Centre Hospitalier Universitaire<br />

Vaudois, Switzerland<br />

3 The incidence and risk factors for dementia before and after stroke<br />

in Polish hospital-based study<br />

A. Klimkowicz, T. Dziedzic, R. Polczyk, J. Pera, A. Slowik, A. Szczudlik,<br />

Jagiellonian University, Poland<br />

4 Diagnosis of major depression in subcortical vascular<br />

encephalopathy<br />

L. Pantoni, M. Martini, L. Bartolini, M. Lamassa, G. Carlucci, G. Pracucci,<br />

D. Inzitari, Department of N<strong>eu</strong>rological and Psychiatric Sciences,<br />

University of Florence, Italy<br />

5 Reduced N-acetylaspartate/creatine ratio in the frontal lobes of<br />

stroke patients with apathy<br />

L. Glodzik-Sobanska, A. Slowik, P. Szermer, J. Kozub, B. Sobiecka, A. Urbanik,<br />

A. Szczudlik, Institute of N<strong>eu</strong>rology, Jagiellonian University, Poland<br />

6 Vascular lesions in pathological examination:<br />

an international survey<br />

L. Pantoni, V. Palumbo, C. Sarti, I. Alufuzoff, J. Jellinger, D. Munoz, J. Ogata,<br />

Department of N<strong>eu</strong>rological and Psychiatric Sciences, University of Florence,<br />

Italy<br />

Epilepsy and Stroke<br />

1 Epilepsy related to cerebrovascular diseases. Natural history and<br />

outcome<br />

E. Palomeras, P. Fossas, A. Cano, P. Sanz, Hospital de Mataró, Spain<br />

73


Poster Sessions Thursday, May 22, 2003<br />

74<br />

Immunology and Infection in Stroke<br />

1 N<strong>eu</strong>rocysticercosis and subarachnoid hemorrhage (SAH):<br />

infectious or congenital an<strong>eu</strong>rysm?<br />

A.R. Rodríguez-Campello, J.R. Roquer, M.G. Gomis, A.O. Ois, V.P. Puente,<br />

Hospital del Mar, Spain<br />

2 Stroke and chronic HCV infection. Clinical and radiologic analysis<br />

of a series<br />

A. Ponz, R. Chamarro, R. Gil, J.V. López-Mut, J. Soler, J.M. Láinez, Servicio de<br />

N<strong>eu</strong>rología and Unidad de RMN-ERESA, Hospital Clínico Universitario, Spain<br />

IMT Ultrasound<br />

1 Soluble intercellular adhesion molecule-1 is an independent<br />

predictor of the development of carotid atherosclerosis<br />

K. Kondo, K. Kitagawa, H. Hougaku, Y. Nagai, H. Yamagami, T. Hoshi,<br />

H. Hashimoto, M. Matsumoto, M. Hori, Osaka University Graduate School of<br />

Medicine, Japan<br />

2 Clinical significance of posterior communicating artery (P-com)<br />

detected by transcranial Doppler (TCD): correlation with MR<br />

angiography (MRA)<br />

S. Park, E. Song, Y. Lee, College of Medicine, Seoul National University,<br />

South Korea<br />

3 Carotid artery intima-media-thickness as a predictor for cerebral<br />

lacunar infarction<br />

H. Soda, V. Ziegler, S. Schlesinger, D. St<strong>eu</strong>be, B. Griewing, N<strong>eu</strong>rologische<br />

Klinik, Rhön Klinikum, Germany


Genetic Disorders<br />

1 Connection between p53 gene Bam HI RFLP polymorphism and the<br />

volume of brain infarction in patients with carotid atherothrombotic<br />

ischemic stroke<br />

V.I. Skvortsova, P.A. Slominsky, E.A. Koltsova, L.V. Gubsky, I.M. Shetova,<br />

T.I. Tupitsina, I.A. Platonova, S.A. Limborska, Russian State Medical<br />

University, Institute of Molecular Genetics, Russian Federation<br />

2 Polymorphisms of the human ER-alpha gene and ischaemic stroke<br />

J. Ch<strong>eu</strong>ng, D. St Clair, M.J. MacLeod, University of Aberdeen, United Kingdom<br />

3 Molecular analysis of Notch3 gene in Spanish CADASIL families<br />

I. Ampuero, A. Cervelló, D. Muñoz, D. Mayo, R. San Pablo, C. San Pablo,<br />

B. José, C. Arnal, J. García de Yébenes, J. Hoenicka, Banco de Tejidos para<br />

Investigaciones N<strong>eu</strong>rológicas de Madrid, Spain<br />

4 Plasma homocysteine level, methylenetetrahydrofoliate gene<br />

mutations and risk for ischemic stroke<br />

J. Jakobkiewicz-Banecka, Z. Banecka-Majkutewicz, W.M. Nyka, G. Wegrzyn,<br />

A. Wegrzyn, W. Sawula, B. Banecki, Medical University of Gdansk, Poland<br />

5 Misdiagnosis of Notch3 mutation-positive CADASIL pedigrees in the<br />

West of Scotland<br />

S.S.M. Razvi, R. Davidson, I. Bone, K.W. Muir, Southern General Hospital,<br />

United Kingdom<br />

6 Whole genome search for a candidate locus involved in cervical<br />

artery dissection<br />

C. Grond-Ginsbach, B. Moormann, S. Hyrenbach, T. Wiest, U. Müller,<br />

I. Hausser, O. Busse, T. Brandt, University of Heidelberg, Germany<br />

7 Ischemic stroke: the impact of genetic variants in genes associated<br />

with hypertension<br />

K. Hsieh, W. Lalouschek, S. Greisenegger, D. Haering, M. Reisinger,<br />

M. Janisiw, G. Endler, W. Lang, S. Cheng, C. Mannhalter, AKH Wien,<br />

University Vienna, Austria<br />

75


Poster Sessions Thursday, May 22, 2003<br />

76<br />

8 Vascular risk factors in cerebral autosomal dominant arteriopathy<br />

with subcortical infarcts and l<strong>eu</strong>koencephalopathy (CADASIL):<br />

worthy to think about it<br />

C. Sarti, L. Pantoni, P. Nencini, S. Bianchi, M. Lamassa, A.M. Basile,<br />

R. Kalaria, M.T. Dotti, A. Federico, D. Inzitari, Department of N<strong>eu</strong>rological and<br />

Psychiatric Sciences, University of Florence, Italy<br />

9 Apoe genotype and distribution of cerebral artery atherosclerosis<br />

in patients with stroke<br />

M. Millan, N. Vila, N. Riutort, S. Garcia, X. Ferrer, J.L. Becerra, M. Lozano,<br />

M.C. Pastor, D. <strong>Esc</strong>udero, University Hospital Germans Trias i Pujol, Spain<br />

Interesting Cases<br />

1 Bilateral spontaneous dissection of the internal carotid arteries<br />

A. Spalloni, M. Ferrari, M. Beccia, A. Bracalello, M. Rasura, Policlinico<br />

S. Andrea II, Facoltà di Medicina, Università di Roma "La Sapienza", Italy<br />

2 Five further cases of spontaneous recanalisation during transcranial<br />

Doppler insonation – is this enhanced endogenous thrombolysis?<br />

P. Syme, Borders General Hospital, University of Edinburgh, United Kingdom<br />

3 Reversible cerebral angiopathy: efficacy of intravenous nimodipine<br />

V. Domigo, C. Lamy, V. Rusu, E. Touzé, D. Trystram, M. Zuber, J.L. Mas,<br />

Hôpital Sainte-Anne, France<br />

4 Isolated leptomenigeal amyloid angiopathy presenting as recurrent<br />

subarachnoid cerebral hemorrhage (SAH)<br />

O. Sedlaczek, L. Achtnichts, S. Zoubaa, E. Grips, T. Kinfe, A. Gass,<br />

M.G. Hennerici, Dept. of N<strong>eu</strong>rology Mannheim, University of Heidelberg,<br />

Germany<br />

5 Blue Rubber Bleb Nevus Syndrome (BRBNS)<br />

M. Spitz, A.R. Massaro, S.M.F. Malheiros, H.B. Ferraz, A.A. Gabbai,<br />

Universidade Federal de Sao Paulo, Brazil


6 Bilateral internal carotid artery dissection mimicking<br />

inflammatory-demyelinating disease<br />

C. Lie, S. Schwenk, C. Szabo, O. Lanczik, M.G. Hennerici, A. Gass,<br />

Universitätsklinikum Mannheim, Germany<br />

7 Ischaemic stroke: an uncommon finding of Eales' disease<br />

C.B. De Cock, S.B. Blecic, M. Dagonnier, J. Jacquy, CHU de Charleroi, Belgium<br />

8 Multiple cerebral infarctions during systemic tissue plasminogen<br />

activator (tPA) treatment due to aortic thrombus fragmentation<br />

S.G. Busse, A. Heinrich, A. Hummel, S. Otto, A. Dressel,<br />

University of Greifswald, Germany<br />

9 Ischemic stroke as first manifestation of acute myeloid l<strong>eu</strong>kemia<br />

M. Xifaras, I. Markakis, E. Alexiou, M. Vikelis, A. Tsakiris, General Hospital of<br />

Nikea-Pir<strong>eu</strong>s, Greece<br />

10 Complex auditory and complex visual hallucinations in two cases of<br />

pontine infarctions<br />

L.C. Álvaro, I. Aranzabal, M.M. Freijo, H. García, J.M. Uterga, F. Sádaba,<br />

Department of N<strong>eu</strong>rology, Basurto Hospital, Spain<br />

11 Spontaneous recanalisation of acute symptomatic internal carotid<br />

artery occlusion<br />

S. Calleja, R. Lopez-Roger, J.M. Llaneza, V. de la Vega, J.M. Gutierrez,<br />

C.H. Lahoz, Hospital Universitario Central de Asturias, Spain<br />

12 Catastrophic antiphospholipid antibody syndrome:<br />

hyperacute evolution from acute abulia to multi-organ-failure<br />

D. Ulbricht, F. Macian, R.J.Metz, Centre Hospitalier de Luxembourg,<br />

Luxemburg<br />

13 Spinal cord ischemia: better outcome than previously thought?<br />

D. Ulbricht, F.M. Huber, F. Macian, R.J. Metz, Centre Hospitalier de<br />

Luxembourg, Luxemburg<br />

14 Subarachnoidal hemorrhage from a venous angioma<br />

A. Lovrencic-Huzjan, Z. Rumboldt, V. Vukovic, V. Demarin,<br />

University Hospital "Sestre milosrdnice", Croatia<br />

77


Poster Sessions Thursday, May 22, 2003<br />

78<br />

15 Transient blurred vision as the only manifestation of basilar stenosis<br />

P. Irimia, J. Sepulcre, M. Moya, C. Barbosa, E. Martínez-Vila,<br />

Clínica Universitaria, Universidad de Navarra, Spain<br />

16 Coexistance of MELAS syndrome and focal segmental<br />

glomerulosclerosis as the clinical phenotype of A3243G point<br />

mutation<br />

S.H. Kim, J. Kim, M.H. Kim, K.Y. Lee, Y.J. Lee, H.T. Kim, Hanyang University,<br />

South Korea<br />

17 Coexistance of MELAS syndrome and focal segmental<br />

glomerulosclerosis as the clincial spectrum of A3243G point<br />

mutation<br />

S. Kim, J. Kim, M.H. Kim, H. Kim, K.Y. Lee, Y.J. Lee, Hanyang University,<br />

South Korea<br />

18 A woman with headache and a prolonged but reversible hemiplegia<br />

M. Langedijk, G.J. Luijckx, J.H. De Keyser, University Hospital Groningen,<br />

The Netherlands<br />

19 Recurrent arterial ischaemic stroke in three successive pregnancies:<br />

a 1-in-1,000,000,000,000 chance?<br />

S.T. Pendlebury, P.M. Rothwell, Stroke Prevention Research Unit,<br />

Department of Clinical N<strong>eu</strong>rology, University of Oxford, United Kingdom


Friday, May 23, 2003<br />

Poster Session II<br />

Chairs: L. Csiba, Hungary, T. Els, Germany, A. Hetzel, Germany and<br />

K. Lees, United Kingdom<br />

Risk Factors and Etiology<br />

1 Metabolic risk factors and carotid intima-media thickness<br />

Y.J. Kim, K.G. Choi, K.D. Park, Korean Metabolic Syndrome Study,<br />

EWHA Womans University, South Korea<br />

2 Genetic variations of the immune system modulate the relation<br />

between acute infections and ischemic cerebrovascular events<br />

W. Lalouschek, G. Endler, K. Hsieh, S. Greisenegger, S. Rieger, W. Lang,<br />

C. Mannhalter, University Clinic of N<strong>eu</strong>rology Vienna, Austria<br />

3 Levels of alpha-1-antitrypsin in plasma and risk of spontaneous<br />

cervical artery dissections: a case-control study<br />

I. Isern, N. Vila, M. Millán, N. Perez de la Ossa, S. Garcia, X. Ferrer, M. Lozano,<br />

N. Riutort, M.C. Pastor, D. <strong>Esc</strong>udero, University Hospital Germans Trías i Pujol,<br />

Spain<br />

4 Mechanisms and etiologies in different vascular territories in young<br />

stroke patients<br />

A. Anziani, M. Beccia, C. Marsiglia, F. Di Lisi, M. Rasura, University of Roma<br />

“La Sapienza”, Italy<br />

5 Clinical characteristics and 90-day outcome of Asian patients with<br />

transient ischeamic attack<br />

R. Esagunde, C. Chen, F. Lateef, H.M. Chang, National N<strong>eu</strong>roscience Institute,<br />

Singapore General Hospital Campus, Singapore<br />

6 Early risk of recurrent stroke by aetiological subtype: implications for<br />

stroke prevention<br />

J. Lovett, A. Coull, P. Rothwell, Stroke Prevention Research Unit, University<br />

Department of Clinical N<strong>eu</strong>rology, Radcliffe Infirmary, United Kingdom<br />

79


Poster Sessions Friday, May 23, 2003<br />

80<br />

7 The Stroke Prevention in Northumberland Study II (SPIN II):<br />

risk factors for first ever stroke in older people in the UK<br />

J. Greenaway, T. Davies, H. Rodgers, N. Stehen, R. Thomson, R. Wood,<br />

SPIN II Team, University of Newcastle-upon-Tyne, United Kingdom<br />

8 Elevated homocysteine is associated with widespread atherosclerosis<br />

and peripheral artery disease in acute ischaemic stroke patients<br />

A. Sim, G. Ho, D. Neo, S. Tsang, H.H. The, H.M. Chang, A. Auchus,<br />

M.C. Wong, C. Chen, National N<strong>eu</strong>roscience Institute, Singapore General<br />

Hospital Campus, Singapore<br />

9 POLymorphisms and Risk of Ischemic Stroke (POLARIS) study:<br />

rationale and design<br />

D.M.O. Pruissen, A. Algra, POLARIS Study Group, University Medical Center<br />

Utrecht, The Netherlands<br />

10 Plasma homocysteine level and other vascular risk factors in patients<br />

in acute phase with ischemic stroke<br />

Z. Banecka-Majkutewicz, W.M. Nyka, G. Wegrzyn, W. Sawula,<br />

J. Jakobkiewicz-Banecka, B. Banecki, Medical University of Gdansk, Poland<br />

11 CT angiography in the analysis of patients with stroke in the territory<br />

of the posterior cerebral artery<br />

A. van der Lugt, D. Siepman, C. de Monye, F. Govaere, H. Tanghe, D. Dippel,<br />

Erasmus MC Rotterdam, The Netherlands<br />

12 Are there differences in the risk factor profiles of lacunar and<br />

non-lacunar infarcts? A systematic review<br />

C. Jackson, C. Sudlow, University of Edinburgh, United Kingdom<br />

13 Fall in blood pressure (BP) during 24 first hours stroke onset but not<br />

basal BP is an independent risk factor in progressing stroke<br />

M. Blanco, R. Leira, J. Serena, A. Davalos, J. Castillo, Hospital Clínico<br />

Universitario de Santiago de Compostela, Spain<br />

14 Plasma homocysteine levels in patients with mild or moderate<br />

ischemic stroke<br />

E. Haapaniemi, J. Helenius, L. Soinne, M. Syrjälä, M. Kaste, T. Tatlisumak,<br />

Helsinki University Central Hospital, Finland


15 Factors predictive of and associated with poor prognosis in lacunar<br />

infarctions<br />

J. Castillo, J. Serena, M. Blanco, R. Leira, A. Davalos, Servicios de<br />

N<strong>eu</strong>rología, Hospital Clínico Universitario de Santiago de Compostela, Spain<br />

16 Genetic variation of the intestinal fatty-acid binding protein 2 (FABP2)<br />

gene and the risk of acute cerebrovascular disease. A case-control<br />

study<br />

P. Wanby, P. Palmqvist, L. Brattström, I. Rydén, M. Carlsson, Department of<br />

Internal Medicine, Kalmar County Hospital, Sweden<br />

17 Microhaemorrhages on MR – frequency and association with lacunar<br />

stroke and periventricular white matter hyperintensities<br />

J.M. Wardlaw, G. Alsop, M.S. Dennis, S.L. Keir, University of Edinburgh,<br />

United Kingdom<br />

18 Common polymorphisms of the protein Z gene are negatively<br />

associated with plasma levels and the risk of cerebral ischemia in<br />

the young<br />

C. Lichy, T. Dong-Si, J. Genius, T. Dolan, T. Hampe, S. Kropp, F. Stoll, K. R<strong>eu</strong>ner,<br />

C. Grond-Ginsbach, A. Grau, University of Heidelberg, Germany<br />

19 Differences in the profile of risk factors between nocturnal and<br />

diurnal lacunar strokes<br />

K. Matz, K. Sebek, A. Herrmann, M. Steiner, A. Dachenhausen, M. Brainin,<br />

Center for Postgraduate Studies in N<strong>eu</strong>rosciences, Danube University and<br />

N<strong>eu</strong>rological Department, Donauklinikum Gugging, Austria<br />

20 Hypercholesterolaemia, not hypocholesterolaemia is a risk factor for<br />

spontaneous intracerebral hemorrhage in the Olomouc region,<br />

Czech Republic<br />

R. Herzig, I. Vlachova, J. Mares, B. Krupka, M. Gabrys, H. Vaverkova,<br />

D. Sanak, A. Bartkova, P. Schneiderka, S. Burval, Clinic of N<strong>eu</strong>rology,<br />

Stroke Center, Faculty Hospital, Czech Republic<br />

21 Risk factors and clinical features of sensorimotor stroke<br />

A. Arboix, E. Solà, M. Castillo, M. Oliveres, E. Comes, M. Balcells, C. Targa,<br />

J. Massons, L. García-Eroles, Sagrat Cor Hospital of Barcelona, Spain<br />

81


Poster Sessions Friday, May 23, 2003<br />

82<br />

22 Ethnic differences in markers of thrombophilia – implications for the<br />

investigation of ischaemic stroke in multi-ethnic populations<br />

P. Jerrard-Dunne, A. Evans, R. McGovern, C. Hajat, L. Kalra, A.G. Rudd,<br />

C.D. Wolfe, H.S. Markus, St. Georges Hospital Medical School, United Kingdom<br />

23 Hashimoto-thyreoiditis associated encephalopathy as a risk factor of<br />

ischemic stroke<br />

M. Landgrebe, K. Winbeck, B. Conrad, D. Sander, Technical University of<br />

Munich, Germany<br />

24 Different risks of body mass index for stroke subtypes: a prospective<br />

study in Korean men<br />

S.Y. Song, S.J. Sung, E.S. Ebrahim, Department of Family Medicine, Samsung<br />

Medical Center, Sungkyunkwan University, South Korea<br />

25 Remnant lipoprotein and lipoprotein (A) as risk factors of stroke and<br />

carotid disease<br />

S. Uchiyama, T. Nakamura, K. Miyazaki, Y. Kimura, Y. Tsutsumi, M. Iwata,<br />

Tokyo Women's Medical University, Japan<br />

26 Role of tissue factor in thrombogenecity of advanced carotid<br />

atherosclerotic plaques<br />

E. Catena, J. Krupinski, R. Vila, M. Cairols, F. Rubio, L. Badimon,<br />

Hospital Universitario de Bellvitge, Spain<br />

27 Does the risk factor determine the severity of stroke?<br />

A.D. Kuljic-Obradovic, M. Savic, S. Atic, B. Kulijc, Hospital for Cerebrovacular<br />

Diseases “St. Sava”, Yugoslavia<br />

28 Body fat distribution and prediction of stroke mortality over 23 years<br />

D. Tanne, U. Goldbourt, Sheba Medical Center, Israel<br />

29 Recurrent thromboembolic events and platelet function status in<br />

the patients with antiphospholipid syndrome using aspirin<br />

V.G. Karepov, V. Karataev, Y. Levi, METEOR Medical Center, Internal Medicine,<br />

Medical Center Tel Hashomer, Israel


30 Obstructive sleep apnea syndrome respirator disease during sleep<br />

n<strong>eu</strong>rological disease in alertness<br />

V. Mastorodimos, G. Klados, A. Plaitakis, University Hospital of Crete, Greece<br />

31 Aspirin resistance as possible risk factor in stroke occurrence<br />

N. Patsouros, P. Laloux, B. Chatelain, C. Chatelain, Cliniques Universitaires<br />

UCL Mont-Godinne, Service de N<strong>eu</strong>rologie, Service d'Hématologie, Belgium<br />

32 Vascular risk factors for first-ever ischemic stroke in Taiwan:<br />

a hospital-based case-control study<br />

T. Tan, K.C. Chang, M.C. Tseng, C.W. Liou, Chang Gung Memorial Hospital,<br />

Taiwan<br />

33 Recanalisation of cervical artery dissections: influencing factors and<br />

role in n<strong>eu</strong>rological outcome<br />

V. Caso, M. Paciaroni, F. Corea, M. Haman, P. Milia, G.P. Pellicioli, L. Parnetti,<br />

V. Gallai, Department of N<strong>eu</strong>roscience, Italy<br />

34 Serum lipoprotein (a) as an independent marker of the severity of<br />

intracranial large-vessel atherosclerosis. A case-control study<br />

J.F. Arenillas, C.A. Molina, P. Chacon, A. Rovira, J. Montaner, E. Sanchez,<br />

M. Quintana, A. Penalba, J. Alvarez-Sabín, Cerebrovascular Unit,<br />

Department of N<strong>eu</strong>rology, Vall d'Hebron University Hospital, Spain<br />

35 A one year follow-up intracranial asymptomatic arterial stenosis<br />

study<br />

S. Bustos, J. Carneado, J.M. Molto, R. Hernandez, T. Frutos, F. Gracia,<br />

A. Garcia-<strong>Esc</strong>riva, M. Alvarez, J. Matias-Guiu, Hospital General Universitario<br />

Alicante, Spain<br />

36 Hyperhomocysteinemia is an independent risk factor for silent brain<br />

infarcts<br />

A. Byung-Ok Choi, K.G. Choi, K.D. Park, College of Medicine,<br />

Ewha Women’s University, South Korea<br />

37 Snoring: a risk factor for stroke and myocardial infarction<br />

A.A. Roxas, S. Sawit, J. Cabildo, Medical City Hospital, Philippines<br />

83


Poster Sessions Friday, May 23, 2003<br />

84<br />

38 Stroke among inpatients: retrospective analysis of a hospital series<br />

L.C. Álvaro, J. Timiraos, M.M. Freijo, F. Sádaba, C. Cortina, Basurto Hospital,<br />

Spain<br />

39 Association of parental history of stroke with clinical parameters in<br />

patients with ischemic stroke or transient ischemic attack<br />

S. Tentschert, S. Greisenegger, K. Hsieh, W. Lang, W. Lalouschek, Vienna<br />

Stroke Study Group, University Hospital of Vienna, Austria<br />

40 Platelet glycoprotein Ib alfa gene dimorphism Thr145Met is<br />

associated with a risk for stroke due small vessel disease<br />

A. Slowik, D. Partyka, T. Dziedzic, P. Szermer, W. Turaj, L. Sobanska,<br />

A. Dziubek, A. Haefele, D.A. Figlewicz, A. Szczudlik, Collegium Medicium,<br />

Jagiellonian University, Poland<br />

41 Hyperhomocysteinemia and inherited thrombophilic risk factors in<br />

young adults with ischemic stroke<br />

G.B. Boncoraglio, M.R. Carriero, E. Ciceri, E. Ciusani, A. Solari, E.A. Parati,<br />

National N<strong>eu</strong>rological Institute “Carlo Besta”, Italy<br />

42 What is the diagnostic yield between lacunar and territorial<br />

cryptogenic young stroke patients<br />

G.J. Luijckx, S. de Jong, J. Lodder, University Hospital Groningen,<br />

The Netherlands<br />

43 Gender-associated differences in ischemic stroke risk, severity and<br />

outcome: an analysis based on the International Stroke Trial<br />

M. Niewada, A. Kobayashi, S.C. Lewis, P.A.G. Sandercock, A. Czlonkowska,<br />

Warsaw Medical University, Poland<br />

44 Plasma homocysteine level in stroke patients – the Indian experience<br />

A. Rohatgi, S. Bhargava, C.S. Agarwal, L.M. Srivastav, Sir Gangaram Hospital<br />

New Dehli, India<br />

45 Family history of intracranial haemorrhage in adults with a brain<br />

arteriovenous malformation: prospective, population-based study<br />

J.M. Hall, R. Al-Shahi, C.P. Warlow, J.N. Berg, SIVMS Steering Committee,<br />

University of Edinburgh, United Kingdom


46 The -148 C/T fibrinogen polymorphism and fibrinogen levels in<br />

patients with ischemic stroke. A case-control study<br />

D.W. Dippel, M.P. van Goor, G.J. Brouwers, E.B. Gomez Garcia, P.J. Koudstaal,<br />

F.W. Leebeek, Erasmus Medical Center, The Netherlands<br />

47 The plasminogen-activator inhibitor type 1 (PAI-1) 4G/5G promotor<br />

polymorphism and PAI-1 levels in patient with ischemic stroke.<br />

A case-control study<br />

D.W. Dippel, M.P. van Goor, G.J. Brouwers, E.B. Gomez Garcia, P.J. Koudstaal,<br />

F.W. Leebeek, Erasmus Medical Center, The Netherlands<br />

48 Isolated cerebral vasculitis. A disease frequently misdiagnosed as<br />

recurrent cryptogenic strokes<br />

K.H. Pedersen, S.M. Jeangette, N. Mavroudakis, M. Pandolfo, S.A. Blecic,<br />

Erasme Hospital, Belgium<br />

49 Marburg I polymorphism of factor VII activating protease.<br />

A prominent risk predictor of carotid stenosis<br />

S. Kiechl, J. Willeit, T. Weimer, A. Mair, P. Santer, C.J. Wiedermann,<br />

J. Roemisch, University Clinic Innsbruck, Austria<br />

50 Mild, moderate and severe carotid stenosis: relation to<br />

cardiovascular risk factors in patients with acute ischemic stroke<br />

A. Chrysanthopoulou, G. Gioldasis, G. Terzis, A. Kalogeropoulos,<br />

T. Papapetropoulos, University Hospital Patras, Greece<br />

51 Reduced levels of plasma EC-SOD, a protector against oxidative<br />

stress, in acute stroke patients<br />

P.G. Wiklund, S.L. Marklund, P. Nilsson, K. Asplund, Dept. of Public Health<br />

and Clinical Medicine, Umeå University, Sweden<br />

52 Ischemic stroke and hyperhomocysteinemia: lack of guidelines for<br />

management<br />

A.L. Rebocho, I. Henriques, L. Domingues, M. Graca, Hospital Espirito Santo,<br />

Portugal<br />

53 Platelet-l<strong>eu</strong>kocyte interaction and platelet activation in migraine.<br />

A link to ischemic stroke?<br />

J.A. Zeller, K. Frahm, R. Stingele, G. D<strong>eu</strong>schl, Christian-Albrechts University<br />

Kiel, Germany<br />

85


Poster Sessions Friday, May 23, 2003<br />

86<br />

54 Increased platelet-l<strong>eu</strong>cocyte aggregation in patients with acute<br />

ischemic stroke<br />

J.A. Zeller, A. Lenz, R. Stingele, G. D<strong>eu</strong>schl, Christian-Albrechts University<br />

Kiel, Germany<br />

55 Does smokeless tobacco increase the risk of stroke?<br />

K. Asplund, S. Nasic, U. Janlert, B. Stegmayr, Department of Public Health<br />

and Clinical Medicine, Sweden<br />

N<strong>eu</strong>roimaging: MRI and fMRI<br />

1 Evidence of vicarious function for the human motor cortex:<br />

a longitudinal fMRI study after primary motor area stroke<br />

A. Jaillard, C. Delon Martin, K. Garambois, J.F. Lebas, M. Hommel,<br />

Universitary Hospital of Grenoble, France<br />

2 Transient global amnesia with hippocampal ischemic lesions –<br />

a report of two cases<br />

P. Kapeller, S. Horner, B. Melisch, K. Petrovic, C. Enzinger, E. Ott, F. Fazekas,<br />

Karl Franzens University Graz and MRI Centre, Austria<br />

3 Intra-arterial high signal on fluid attenuated inversion recovery<br />

images (IHS-FLAIR) in acute ischemic stroke on MCA territory<br />

B.C. Lee, J.S. Bae, K.H. Yu, J. S<strong>eu</strong>ng-Cheol, M. Hyeo-il, Hallym University<br />

College of Medicine, South Korea<br />

4 Withdrawn by author<br />

5 Clinical significance of dominant ipsilateral posterior cerebral artery<br />

on magnetic resonance angiography in acute ischemic stroke<br />

J.H. Lee, S.J. Han, W.Y. Kang, K.H. Lee, I.S. Choi, K.H. Yu, H.K. Song,<br />

College of Medicine, Hallym University, South Korea<br />

6 Infarct growth in acute stroke predicted by MR perfusion and<br />

diffusion weighted imaging<br />

F. Schneider, A.C. Januel, L. Court, P. Garnier, M. Homel, A. Jaillard,<br />

S. Laporte, A. Viallon, D. Michel, F.G. Barral, CHU de Saint Etienne, France


7 Relationship of the Apparent Diffusion Coefficient (ADC) decrease<br />

with penumbra and infarct core as defined by PET in acute ischaemic<br />

stroke<br />

J. Guadagno, E. Warburton, T. Fryer, F. Aighuiro, C. Price, S. Harding, J. Gillard,<br />

J. Clark, A. Carpenter, J.C. Baron, Cambridge University, Dept. of N<strong>eu</strong>rology<br />

and Stroke, Wolfson Brain Imaging Centre, United Kingdom<br />

8 Validity and reliability of flair technique measuring cerebral infarct<br />

volumes<br />

S. Pedraza, C. Guergue, J. Mendez, J. Vera, Y. Silva, A. Davalos,<br />

Hospital Josep Trueta, Spain<br />

9 Evaluation of interscanner variability of ADC data acquisition in<br />

stroke centres in Germany<br />

C. Lie, J. Hirsch, T. Kucinski, J. Junge-Huelsing, M. Siebler, C. Fitzek,<br />

S. Heiland, A. Roether, A. Villringer, A. Gass, M.G. Hennerici,<br />

Universitätsklinikum Mannheim, Germany<br />

10 Perfusion computed tomography and CT angiography in the early<br />

assessment of acute ischemic stroke<br />

J.M. Esteban, V. Cervera, F.M. Gurrea, O. Velez, C. Guillen, ERESA,<br />

Hospital General Universitario de Valencia, Spain<br />

11 “Fogging” on MR after ischaemic stroke – how often does it occur<br />

and does it matter?<br />

A.P. O'Brien, S. Stretton, R.J. Sellar, J.M. Wardlaw, University of Edinburgh,<br />

United Kingdom<br />

12 The effect of ischaemic lesion swelling on serial MR diffusion and<br />

perfusion measurements in stroke<br />

A.C.S. Rivers, P.A. Armitage, T. Carpenter, M.E. Bastin, P.J. Hand, M.S. Dennis,<br />

J.M. Wardlaw, University of Edinburgh, United Kingdom<br />

87


Poster Sessions Friday, May 23, 2003<br />

88<br />

13 Comparison of clinical and n<strong>eu</strong>roradiological characteristics<br />

between internal carotid artery and middle cerebral artery disease<br />

P.H. Lee, S.H. Oh, O.Y. Bang, I.S. Joo, K. Huh, College of Medicine,<br />

Ajou University, South Korea<br />

14 Comparison of clinical and n<strong>eu</strong>roradiological characteristics<br />

between internal carotid artery and middle cerebral artery diseases<br />

P. Lee, S. Oh, O. Bang, I. Joo, K. Huh, College of Medicine, Ajou University,<br />

South Korea<br />

15 MR perfusion imaging: problems resulting from a lack of contrast<br />

agent in infarcted regions<br />

P.A. Armitage, C.S. Rivers, T.K. Carpenter, M.E. Bastin, P.J. Hand,<br />

J.M. Wardlaw, University of Edinburgh, United Kingdom<br />

16 Artefacts in MR perfusion parametric images in ischaemic stroke –<br />

effects of variation in bolus arrival time<br />

T.K. Carpenter, P.A. Armitage, M.E. Bastin, J.M. Wardlaw, University<br />

Edinburgh, United Kingdom<br />

17 N<strong>eu</strong>ro-Behcet’s disease: a clinical and MRI study<br />

N.M. El-Nahas, H.M. Abdel Kader, Ain Shams University, Egypt<br />

18 Improved detection of brainstem infarctions in the first 24 hours using<br />

diffusion-weighted imaging with an optimised spatial resolution<br />

T. Etgen, H. Gräfin von Einsiedel, K. Winbeck, B. Conrad, D. Sander,<br />

Technical University Munich, Germany<br />

19 False-negative diffusion-weighted MR images in hyperacute<br />

ischemic stroke<br />

M.W. Masaki Watanabe, K.I. Keisuke Imai, T.M. Takahisa Mori, T.K. Toshiki<br />

Kamiya, H.I. Hajime Izumoto, Shonan Kamakura General Hospital, Japan<br />

20 Multislice CT angiography for investigation of vertebrobasilar<br />

ischaemia<br />

S.S.M. Razvi, E. Teasdale, C. Santosh, I. Bone, K.W. Muir, Southern General<br />

Hospital, United Kingdom


21 Calcification of intracranial arteries on CT as a marker of<br />

atherosclerosis in stroke patients<br />

N.C. Suwanwela, N. Suwanwela, Chulalongkorn University, Thailand<br />

22 Intracerebral haemorrhage on warfarin at the site of a known<br />

microhaemorrhage on T2* MR imaging – a case report<br />

S.R. Hart, J.M. Wardlaw, A.J. Farrall, P.A. Sandercock, M.S. Dennis,<br />

Dept. of Clinical N<strong>eu</strong>roscience, University of Edinburgh, United Kingdom<br />

23 Cerebral ischemic lesions after unprotected stenting or<br />

entarterectomy in symptomatic proximal internal carotid stenosis:<br />

a prospective diffusion-weighted MRI study<br />

S. Garcia, J. Capellades, J. Muchart, J. Callejas, N. Vila, X. Ferrer,<br />

J.M. Michavila, M. Lozano, D. <strong>Esc</strong>udero, University Hospital Germans<br />

Trias i Pujol, Spain<br />

24 Noninvasive quantitative assessment of Cerebral Blood Flow (CBF)<br />

using 99mTc-ECD SPECT with adjunctive radionuclide angiography in<br />

ischemic stroke<br />

S.H. Kim, J. Kim, M. Kim, H. Kim, Y.Y. Choi, Hanyang University, South Korea<br />

25 Early wallerian degeneration of the pyramidal tract after ischemic<br />

stroke: a diffusion tensor imaging study<br />

G. Thomalla, V. Glauche, C. Weiller, J. Röther, Klinik und Poliklinik für<br />

N<strong>eu</strong>rologie, Universitätsklinikum Hamburg-Eppendorf, Germany<br />

26 Utility of CT perfusion scan in the diagnosis of acute ischemic stroke:<br />

experience in 47 patients<br />

J.M. Esteban, V. Cervera, I. Puchades, S. Roch, V. Ballester, J. Casañ,<br />

ERESA, Hospital General Universitario de Valencia, Spain<br />

27 Cerebral blood flow reduction correlates with CT density decrease in<br />

acute stroke patients<br />

T. Kucinski, A. Majumder, R. Knaab, D. Naumann, J. Fiehler, O. Vaeterlein,<br />

B. Eckert, J. Roether, H. Z<strong>eu</strong>mer, University Hospital Hamburg-Eppendorf,<br />

Germany<br />

89


Poster Sessions Friday, May 23, 2003<br />

90<br />

28 Clinicoradiologic findings of spinal cord injury in decompression<br />

sickness<br />

J.Y. Ahn, M. Kim, J.Y. Kim, Gangnam General Hospital Public Corporation,<br />

South Korea<br />

29 Microbleeding prevalence. Analysis by stroke subtype<br />

R. Gil Gimeno, A. Ponz, R. Chamarro, J.M. Santonja, J.V. López Mut,<br />

J.M. Láinez, Hospital Clínico Universitario de Valencia, Spain<br />

30 Transient decreased activation in lacunar strokes:<br />

a longitudinal fMRI study<br />

K. Garambois, A. Jaillard, C. Delon Martin, J.F. Lebas, M. Hommel,<br />

Universitary Hospital of Grenoble, France<br />

31 Age-related n<strong>eu</strong>ral correlates during a finger-tapping task in normal<br />

subjects: a fMRI study<br />

A. Jaillard, K. Garambois, C. Delon Martin, J.F. Lebas, M. Hommel,<br />

Universitary Hospital of Grenoble, France<br />

Recovery and Rehabilitation<br />

1 The effects of an individualised information booklet in post stroke<br />

patients: the care file project<br />

D. Lowe, M. Leathley, A. Sharma, University Hospital Aintree, United Kingdom<br />

2 IMPACCTS – Improving Patient And Carer Communication, Team<br />

working and goal Setting – in stroke rehabilitation<br />

J. Monaghan, A.K. Sharma, D. McDowell, Stroke Team for Audit and<br />

Research, University Hospital Aintree, United Kingdom<br />

3 A case for improved post-stroke follow-up<br />

L.N. Smith, M.I. Lawrence, S.M. Kerr, P. Langhorne,<br />

K.R. Lees, University of Glasgow, United Kingdom<br />

4 Early supported discharge services for stroke patients:<br />

an individual patient data meta-analysis<br />

P. Langhorne, Early Supported Discharge Trialists, Academic Section of<br />

Geriatric Medicine, University of Glasgow, United Kingdom


5 Augmented physiotherapy after stroke: a randomised controlled trial<br />

P. Langhorne, Glasgow Augmented Physiotherapy after Stroke (GAPS) Study<br />

Group, Academic Section of Geriatric Medicine, University of Glasgow,<br />

United Kingdom<br />

6 National audit of stroke secondary prevention in the United Kingdom<br />

A.G. Rudd, A. Hoffman, D. Lowe, P. Irwin, M. Pearson, Royal College of<br />

Physicians London, United Kingdom<br />

7 Development of a comprehensive description of hands-on therapy<br />

for the hemiplegic upper limb and a treatment schedule to record<br />

individual treatments<br />

S.M. Hunter, P. Crome, J. Sim, V.M. Pomeroy, Keele University,<br />

United Kingdom<br />

8 Community stroke groups for patients with aphasia after stroke:<br />

users views of criteria for effectiveness<br />

L.A. Legg, D. Clark, Glasgow University, United Kingdom<br />

9 Bilateral paramedian thalamic infarcts. Evolution in six cases<br />

F. Macian, L. Magy, C. Chastagner, M. Khalil, J.M. Vallat,<br />

CHRU Dupuytren, France<br />

10 Social effects on patients after a stroke incident (SI)<br />

P. Heras, A. Argyriou, S. Karagiannis, M. Corcondilas, D. Mitsibounas,<br />

General Hospital of Kos, Greece<br />

11 Biological factors associated with late post-stroke depression:<br />

preliminary results of a case-control study<br />

K. Chatterjee, D.H. Barer, Stroke Research Unit, Queen Elizabeth Hospital,<br />

United Kingdom<br />

12 Faecal incontinence after stroke varies with time from onset and<br />

stroke sub-type<br />

J.A. Barrett, H. Pandya, V. Little, P. Weir, M.E. Barrett, G. Sangster, R. Plant,<br />

M. Pritchard Howarth, C. Jack, C.L. Watkins, Wirral Stroke Service,<br />

United Kingdom<br />

91


Poster Sessions Friday, May 23, 2003<br />

92<br />

Management/Economics<br />

1 An urban stroke project – enhancing logistics to treat more patients<br />

with rtPA faster<br />

M. Fritzinger, O. Mielke, M. Daffertshofer, M.G. Hennerici, Dept. of N<strong>eu</strong>rology<br />

Mannheim, University of Heidelberg, Germany<br />

2 A pilot evaluation of a new secondary prevention intervention:<br />

lessons for current practice<br />

J. Redfern, C. McKevitt, A. Rudd, C. Wolfe, King's College London,<br />

United Kingdom<br />

3 Medical resource use and costs of patients with acute stroke during<br />

twelve months after acute hospital stay<br />

K. Rossnagel, J. Müller-Nordhorn, D. Menke, C.H. Nolte, G.J. Jungehuelsing,<br />

A. Reich, A. Villringer, S.N. Willich, Institute of Social Medicine, Epidemiology<br />

and Health Economics, Charité, Germany<br />

4 Stroke unit vs. general n<strong>eu</strong>rology ward. A diagnosis related group<br />

based study<br />

J. Matías-Guiu, J. Aranaz-Andrés, F. Gracia-Fleta, J. Carneado-Ruiz,<br />

J. Hernández-Lorido, H.M. Moltó-Jordà, Hospital General Universitari<br />

d'Alacant, Spain<br />

5 The cost of secondary stroke in Poland<br />

M. Niewada, B. Kaminski, A. Kobayashi, A. Czlonkowska, A. Czlonkowski,<br />

Department of Experimental and Clinical Pharmacology, Warsaw Medical<br />

University, Poland<br />

6 Management of acute stroke across Germany: results from the<br />

German Stroke Registries Study Group (ADSR)<br />

P.L. Kolominsky-Rabas, P.U. H<strong>eu</strong>schmann, B. Misselwitz, A. Haass,<br />

K. Lowitzsch, B. N<strong>eu</strong>ndoerfer, K. Berger, Public Health Medicine Research<br />

Unit, University of Erlangen, Germany<br />

7 Medical management of cervical arterial dissections:<br />

a study of routine practice in France<br />

F. Vuillier, L. Tatu, T. Moulin, CHU Besançon, France


8 Costs of acute care of first-ever ischemic stroke in Taiwan<br />

K.C. Chang, M.C. Tseng, Chang Gung Memorial Hospital, Taiwan<br />

9 Resource utilisation and costs of stroke unit care in Germany<br />

A.E. Spottke, C. Haacke, K. Zamzow, S. Pawelzik, M. Rethfeldt, W.H. Oertel,<br />

O. Schöffski, R.C. Dodel, T. Back, University Bonn and University Marburg,<br />

Germany<br />

10 Improving trials in acute stroke using internet randomisation and data<br />

collection<br />

P.M. Bath, S. Y<strong>eu</strong>ng, G. Watson, C.S. Weaver, University of Nottingham,<br />

United Kingdom<br />

11 Ischemic stroke patients with previous TIA: special patients?<br />

R. Pires, I. Henriques, S. Pires-Barata, L. Rebocho, Hospital Espirito Santo<br />

Evora, Portugal<br />

12 Epidemiology of stroke in Martinique, French West Indies<br />

(ERMANCIA study): an assessment of the secondary prevention<br />

3.5 years following a first-ever stroke<br />

D. Smadja, S. Olindo, P. Cabre, P. René-Corail, E. Hars, M. Saint-vil,<br />

University Hospital of Fort-de-France-La Meynard, Martinique<br />

13 Alternative strategies for stroke care: cost-effectiveness analysis<br />

from a prospective randomised controlled trial<br />

A. Patel, M. Knapp, I. Perez, A. Evans, L. Kalra, Guy's, King's and St Thomas'<br />

School of Medicine, King's College London, United Kingdom<br />

Experimental Studies<br />

1 Efficacy of 340 kHz pulsed ultrasound as acute stroke therapy in a rat<br />

model of embolic stroke<br />

M. Fatar, M. Stroick, M.G. Hennerici, M. Daffertshofer, Dept. of N<strong>eu</strong>rology,<br />

Klinikum Mannheim, University of Heidelberg, Germany<br />

2 Evidence for vascular leakage in the photothrombotic model for stroke<br />

E. Hoff, M. OudeEgbrink, V. Heijnen, R. van Oostenbrugge,<br />

University Maastricht, The Netherlands<br />

93


Poster Sessions Friday, May 23, 2003<br />

94<br />

3 Lipid peroxidation and ischemic brain disease<br />

D. Veljancic, R. Raicevic, P. Jovic, T. Lepic, E. Dincic, Military Medical<br />

Academy, Yugoslavia<br />

4 Dose-dependent, n<strong>eu</strong>roprotective effects of citicoline in an<br />

experimental model of brain ischaemia<br />

I. Lizasoain, O. Hurtado, A. Davalos, R. Lozano, J.J. Secades, J. Cleza,<br />

P. Lorenzo, M.A. Moro, J. Castillo, Universidad Complutense Madrid, Spain<br />

5 Histopathological correlates of MR diffusion and perfusion imaging in<br />

animal stroke models<br />

A.C.S. Rivers, J.M. Wardlaw, University of Edinburgh, United Kingdom<br />

6 In vitro ischemic preconditioning produces n<strong>eu</strong>roprotection which is<br />

mediated by up-regulation of glutamate uptake<br />

M.A. Moro, C. Romera, S.H. Botella, O. Hurtado, A. Cárdenas, J.C. Leza,<br />

P. Lorenzo, P. Fernández-Tomé, I. Lizasoain, Departamento de Farmacología,<br />

Universidad Complutense de Madrid, Spain<br />

7 Changes of ceramide level in the rat brain under chronic cerebral<br />

hypoperfusion: biochemical and immunohistochemical study<br />

R. Ohtani, H. Tomimoto, H. Wakita, T. Kondo, M. Watanabe, T. Taguchi,<br />

I. Akiguchi, T. Okazaki, H. Shibasaki, Kyoto University Graduate School of<br />

Medicine, Japan<br />

8 Effects of anti-thrombotic agents on hemorheology in a<br />

microcirculation model<br />

Y. Kimura, S. Uchiyama, Y. Piao, M. Iwata, N<strong>eu</strong>rological Institute,<br />

Tokyo Women’s Medical University, Japan<br />

9 Subacute immobilisation stress increases infarct volume after<br />

permanent focal cerebral ischemia in rats<br />

J.C. Leza, J.R. Caso, J.L. Madrigal, B. Garcia-Bueno, M.A. Moro, I. Lizasoain,<br />

P. Lorenzo, Departamento Farmacologia, Universidad Complutense Madrid,<br />

Spain


10 Inhibition of glutamate release accounts for n<strong>eu</strong>roprotective effects<br />

of tocopherol in experimental stroke<br />

M.A. Moro, M.P. Pereira, A. Cardenas, O. Hurtado, J.L. Madrigal,<br />

J.C. Leza, P. Lorenzo, I. Lizasoain, Departamento Farmacologia,<br />

Universidad Complutense Madrid, Spain<br />

11 In vivo ischemic preconditioning involves up-regulation of TNF<br />

receptor I<br />

I. Lizasoain, J.M. Pradillo, M.P. Pereira, A. Cardenas, J.C. Leza, M.A. Moro,<br />

P. Lorenzo, A. Davalos, J. Castillo, Departamento Farmacologia,<br />

Universidad Complutense Madrid, Spain<br />

12 Evaluation of ischemia induced selective gene expression by<br />

measure of FAS receptor RNA levels in rat brain<br />

M. Alonso de Leciñana, M. Gutierrez, E. Díez-Tejedor, P. Santos, S. Calvo,<br />

M. Sobrado, V. Ceña, Cerebrovascular Research Unit, Hospital La Paz and<br />

Hospital N Sra de Sonsoles, Spain<br />

13 A protease resistant peptide inhibitor of C-JUN N-terminal kinase<br />

provides very strong protection against focal cerebral ischemia<br />

L. Hirt, T. Borsello, P.G.H. Clarke, A. Vercelli, M. Repici, D.F. Schorderet,<br />

J. Bogousslavsky, C. Bonny, Centre Hospitalier Universitaire Vaudois,<br />

Switzerland<br />

14 Early hyperbaric oxygenation rescues n<strong>eu</strong>rons in penumbra and<br />

striatum from ischemic cell death in transient cerebral ischemia in<br />

the rat<br />

C.C. <strong>Esc</strong>henfelder, M. Lou, T. Herdegen, G. D<strong>eu</strong>schl, Christian-Albrechts<br />

University, Germany<br />

95


Poster Sessions Friday, May 23, 2003<br />

96<br />

N<strong>eu</strong>rosurgery/Vascular Surgery<br />

1 Emotional, cognitive, and n<strong>eu</strong>rologic status after carotid surgery<br />

A. Faulstich, P. Marx, B. Mann, A. Hartmann, University Hospital Benjamin<br />

Franklin, Free University Berlin, Germany<br />

2 A grading system for intracranial artereovenous malformations<br />

applicable to endovascular procedures<br />

B.Y. Sheikh, King Faisal University Hospital, Saudi Arabia<br />

3 Extracranial carotid angioplasty and stenting in contralateral<br />

high-degree carotid stenosis or occlusion symptomatic patients<br />

R. González-Santiago, F. Nombela, M. Tamayo, J. Vivancos,<br />

Hospital Universitario De La Princesa, Spain<br />

4 Carotid stenting: our experiencies<br />

B. Zvan, Z. Milosevic, I. Kocijancic, M. Zaletel, University Medical Centre<br />

Ljubljana, Slovenia<br />

5 Carotid angioplasty in patients older than 80:<br />

acute and subacute results<br />

K. Rabe, H. Goedel, R. Perron, I. Boesenberg, K.F. Beykirch, R. Theis, C. Rubel,<br />

W. Pfeil, H. Sievert, Cardiovascular Center Bethanien, Germany<br />

6 Unruptured an<strong>eu</strong>rysms: endovascular treatment.<br />

Experience of 68 cases<br />

J. Izquierdo, E. Vivas, L. Soler, T. Sola, E. Balaguer, L. Guimaraens,<br />

Hospital General de Catalunya, Spain<br />

7 Endovascular treatment in ruptured an<strong>eu</strong>rysms experience in 145 cases<br />

E. Vivas, T. Sola, L. Soler, E. Balaguer, J. Izquierdo, L. Guimaraens,<br />

Hospital General de Catalunya, Spain<br />

8 Anterior circulation large and giant an<strong>eu</strong>rysms: surgical and<br />

endovascular techniques, complications and clinical outcomes<br />

C. Todaro, E. Ciceri, P. Ferroli, C. Marras, A. Franzini, M. Carriero,<br />

G. Boncoraglio, E. Parati, S. Giombini, G. Broggi, Istituto Nazionale<br />

N<strong>eu</strong>rologico “Carlo Besta”, Italy


Cerebral Haemorrhage and SAH<br />

1 Prognostic factors of intracerebral haemorrhage in patients with<br />

previous TIA or ischaemic stroke<br />

M.J. Ariesen, A. Algra, P.M. Rothwell, Cerebrovascular Cohort Studies<br />

Collaboration, University Medical Centre Utrecht, Julius Centre for Health<br />

Sciences and Primary Care, The Netherlands<br />

2 Acute hyperglycemia and outcome after subarachnoid hemorrhage<br />

S. Dorhout Mees, G. van Dijk, A. Algra, D. Kempink, R. Gabriel,<br />

University Medical Center Utrecht, The Netherlands<br />

3 Acute hydrocephalus in subarachnoid hemorrhage:<br />

outcome and complications of treatment<br />

I.S. Beijer, G.W. van Dijk, A. Algra, G.J.E. Rinkel, University Medical Center<br />

Utrecht, The Netherlands<br />

4 Von Willebrand factor as predictor for intracerebral hemorrhage.<br />

A prospective incident case-referent study<br />

L. Johansson, J.H. Jansson, B. Stegmayr, T.K. Nilsson, G. Hallmans, K. Boman,<br />

Department of Public Health and Clinical Medicine, Umeå University Hospital,<br />

Sweden<br />

5 The additional risk of uncontrolled hypertension for intracerebral<br />

hemorrhage in hypertensive patients. A post-mortem, case-control<br />

study<br />

M.A. Ritter, R. Szepesi, K. Hegedüs, D.W. Droste, E.B. Ringelstein, L. Csiba,<br />

UKM Münster, Germany<br />

6 Genetic polymorphisms and outcome after an<strong>eu</strong>rysmal subarachnoid<br />

hemorrhage<br />

Y.M. Ruigrok, A.J. Slooter, A. Bardoel, C.J. Frijns, C. Wijmenga, G.J.Rinkel,<br />

University Medical Center Utrecht, The Netherlands<br />

7 Late recurrent subarachnoid hemorrhage:<br />

patient characteristics and outcome<br />

M.J.H. Wermer, G.J.E. Rinkel, P. Greebe, K.W. Albrecht, C.M. Dirven,<br />

C.A. Tulleken, University Medical Centre Utrecht / Rudolf Magnus Institute for<br />

N<strong>eu</strong>rosciences, The Netherlands<br />

97


Poster Sessions Friday, May 23, 2003<br />

98<br />

8 Long-term functional outcome after an<strong>eu</strong>rysmal subarachnoid<br />

haemorrhage<br />

G.J.E. Rinkel, P. Greebe, A. Algra, Rudolf Magnus Institute of N<strong>eu</strong>roscience,<br />

University Medical Centre Utrecht, The Netherlands<br />

9 Infratentorial location is an independent determinant for hemorrhagic<br />

presentation of brain arteriovenous malformations (AVMs)<br />

A.V. Khaw, J.P. Mohr, R.R. Sciacca, H.C. Schumacher, J. Pile-Spellman,<br />

H. Mast, C. Stapf, Columbia University College of Physicians and Surgeons,<br />

USA<br />

10 Delirium in acute subaracnoid haemorrhage<br />

L. Caeiro, J.M. Ferro, R. Albuquerque, M.L. Figueira, Hospital Santa Maria,<br />

Portugal<br />

Venous Diseases<br />

1 Cerebellar venous infarction: two case reports<br />

S. Calado, J. Graça, I. Palma, C. Ribeiro, M. Viana-Baptista,<br />

Hospital Egas Moniz, Portugal<br />

2 Aseptic cerebral venous thrombosis: a perspective study in an<br />

university hospital in Thailand<br />

K. Phanthumchinda, S. Wanichapol, I. Thaipisuttikul, N.C. Suwanwela,<br />

Faculty of Medicine, Chulalongkorn University, Thailand<br />

3 Third occurrence of cerebral venous thrombosis in a 33-year old<br />

woman<br />

N. Amberger, M. Weih, L. Harms, J. Valdueza, Charité Hospital,<br />

Humboldt University, Germany<br />

4 Seizures after Cerebral Venous Thrombosis (CVT)<br />

A.P. Dutra, E.C. Sa de Camargo, A.R. Massaro, L.A. Bacheschi, M. Scaff,<br />

Universidade de Sao Paulo, Brazil<br />

5 Infarction of spinal cord and pure bilateral brachial paresis<br />

G. Sampaio Silva, A.R. Massaro, R. de Lima Carvalho, L. Azevedo, A.J. Santos,<br />

H.B. Ferraz, A.A. Gabbai, Universidade Federal de Sao Paulo, Brazil


6 Delay in hospital admission of patients with cerebral vein and dural<br />

sinus thrombosis<br />

J.M. Ferro, M.G. Lopes, M.J. Rosas, F. Pita, J. Fontes, VENOPORT Investigators,<br />

Hospital Santa Maria, Portugal<br />

7 Headache in early diagnosis of cerebral venous thrombosis:<br />

clinical experience in 59 patients<br />

S. Iurlaro, A. Ciccone, E. Beghi, A. Gatti, G. Bussone, M. Leone, A. Rigamonti,<br />

P. Santoro, C. Ferrarese, E. Agostani, N<strong>eu</strong>rology Milano-Bicocca University,<br />

San Gerardo Hospital, Niguarda Hospital, C. Besta Institute, Italy<br />

8 Are D-dimer useful in the diagnostic strategy of cerebral venous<br />

thrombosis?<br />

R.F. Sztajzel, P.H. Lalive, P. de Moerloose, K. Lovblad, F. Sarasin,<br />

University Hospital Geneva, Switzerland<br />

9 Isolated headache as the only manifestation of the cerebral venous<br />

thrombosis<br />

A.R. Cumurciuc, I. Crassard, M. Sarov, D. Valade, M.G. Bousser,<br />

Lariboisiere Hospital Paris, France<br />

Meta-Analysis and Review Papers<br />

1 What do qualitative studies of stroke tell us? A literature review<br />

C. McKevitt, J. Redfern, F. Mold, C. Wolfe, King's College London,<br />

United Kingdom<br />

2 Risk of severe intracerebral haemorrhage after rt-PA for ischaemic<br />

stroke in patients with extended ischaemic changes on computed<br />

tomography<br />

V. Larrue, V. Lauwers-Cances, University of Toulouse, France<br />

3 Brain displacement in patients with TND due to CSH<br />

H.G. Sunku, Hinchingbrooke Hospital, United Kingdom<br />

99


Poster Sessions Friday, May 23, 2003<br />

100<br />

4 Optimising the statistical analysis of functional outcome in stroke trials<br />

P.M. Bath, Optimising Analysis of Stroke Trials (OAST) Collaborators,<br />

University of Nottingham, United Kingdom<br />

5 A systematic review of Terson syndrome:<br />

frequency and prognosis in subarachnoid haemorrhage<br />

M.O. McCarron, P.G. McCarron, Royal Victoria Hospital, United Kingdom<br />

6 Medial medullar infarction: clinical manifestations and magnetic<br />

resonance imaging findings<br />

K. Chung, S.M. Lee, S.S. Yoon, D.I. Chang, College of Medicine,<br />

Kyung Hee University, South Korea<br />

Cardiac Disorders and Stroke<br />

1 Detection of cardioembolic dysrythmia using long-term ECG<br />

recording after acute stroke<br />

D. Jabaudon, K. Sievert, H. Sunthorn, J. Sztajzel, R. Sztajzel,<br />

Hôpitaux Universitaires de Genève, Switzerland<br />

2 Aortic arch dissection in potential thrombolysis candidates<br />

M. Bruandet, S. Crozier, M. Obadia, C. Lefevre, A. Chevrel,<br />

Y. Samson, Hôpital de la Salpétrière, France<br />

3 Transcranial Doppler (TCD) in patients with refractory congestive<br />

heart failure (CHF) before and after heart transplantation<br />

S. Malheiros, A.R. Massaro, D.R. Almeida, A.P. Dutra, R.B. Diniz, J.N. Branco,<br />

A.A. Gabbai, Universidade Federal de Sao Paulo, Brazil<br />

4 Cerebral microembolism during transmyocardial laser<br />

revascularisation and strategies for its avoidance<br />

T. Gerriets, M. Grossherr, M. Misfeld, U. Nees, E. R<strong>eu</strong>sche, E. Stolz,<br />

H.H. Sievers, M. Kaps, E.G. Kraatz, University Giessen and University Lübeck,<br />

Germany<br />

5 Interl<strong>eu</strong>kin-6 regulates acute phase reaction in ischemic stroke<br />

T. Dziedzic, A. Klimkowicz, A. Slowik, A. Szczudlik, Jagiellonian University,<br />

Poland


New Clinical Trial Results<br />

1 Is the intervention of an occupational therapist effective in increasing<br />

independence for residents with stroke living in a care home?<br />

C. Sackley, D.T. Wade, D. Mant, University of Oxford, United Kingdom<br />

2 SAFE II Study: why anticoagulants still remain underused in Europe?<br />

Part 2–A survey from n<strong>eu</strong>rologists’ practices after stroke<br />

D. Deplanque, J.L. Mas, V. Gallai, J. Ferro, J. de R<strong>eu</strong>ck, R. Schmidt,<br />

D. Parnetti, D. Leys, SAFE II Investigators, N<strong>eu</strong>rology and Pharmacology<br />

Departments, CHRU de Lille, France<br />

3 Therap<strong>eu</strong>tic benefit of abciximab in acute ischemic stroke as<br />

measured by modified Rankin Scale (mRS) responder analysis<br />

W. Hacke, Universitatsklinikum Heidelberg, Germany<br />

4 The effects of three antiplatelet drugs given singly or together on<br />

platelet and l<strong>eu</strong>cocyte function in healthy subjects and patients with<br />

previous ischaemic stroke<br />

L. Zhao, S. Fletcher, C. Weaver, J. Leonardi-Bee, J. May, S. Fox, S. Heptinstall,<br />

P.M.W. Bath, Centre for Vascular Research, University of Nottingham,<br />

United Kingdom<br />

5 Effects of simvastatin on the progression of white matter changes:<br />

a post-hoc analysis of a randomised, boubled-blind,<br />

placebo-controlled study<br />

K.S. Wong, Y.H. Fan, W.W.M. Lam, T.H. Tsoi, P.W. Ng, ROCAS Study Group,<br />

Chinese University of Hong Kong, Hong Kong<br />

6 Timing of recanalisation and risk of symptomatic intracranial<br />

hemorrhage after iv tPA. The CLOTBUST Collaboration Study Group<br />

C.A. Molina, A.M. Demchuk, M. Saqqur, J.F. Arenillas, J. Montaner,<br />

J. Alvarez-Sabin, A.V. Alexandrov, CLOTBUST Collaboration Study Group,<br />

Hospital Vall d´Hebron, Spain<br />

7 Differential suppression of thromboxane biosynthesis by indobufen<br />

and ASA in patients with ischaemic stroke<br />

S. Ricci, E. Ricciotti, M.G. Celani, E. Righetti, E. Stragliotto, F. Stracci,<br />

P. Patrignani, Stroke Service Perugia, Italy<br />

101


Poster Sessions Friday, May 23, 2003<br />

102<br />

Ongoing Trials<br />

1 The VITATOPS (VITAmins To Prevent Stroke) Trial<br />

G. Hankey, VITATOPS Trial Collaborative Group, Royal Perth Hospital, Australia<br />

2 The Continue Or Stop post-Stroke Antihypertensives Collaborative<br />

Study (COSSACS)<br />

T.G. Robinson, J.F. Potter, COSSAC Study Group, Leicester Warwick Medical<br />

School, United Kingdom<br />

3 Acute Cerebral CT Evaluation Stroke Study (ACCESS)<br />

A.J. Farrall, O. Mielke, R. von Kummer, P. Chmielnik, D. Perry, J.M. Wardlaw,<br />

Division of Clinical N<strong>eu</strong>rosciences, University of Edinburgh, United Kingdom<br />

4 HAMLET Hemicraniectomy After MCA infarction with Life-threatening<br />

Edema Trial<br />

J. Hofmeijer, H.B. van derWorp, G.J. Amelink, A. Algra, J. van Gijn,<br />

L.J. Kappelle, Department of N<strong>eu</strong>rology, UMCU, The Netherlands<br />

5 The Third International Stroke Trial (IST-3)<br />

P. Sandercock, R. Lindley, The Third International Stroke Trial (IST-3)<br />

Collaborative Group, University of Edinburgh,<br />

Department of Clinical N<strong>eu</strong>roscience, United Kingdom<br />

6 Does surface n<strong>eu</strong>romuscular electrical stimulation (sNMES) to the<br />

upper limb following acute stroke improve outcome?<br />

C. Church, R. Curless, S. Huntley, C. Price, D. Pandyan, H. Rodgers,<br />

Departments of Geriatric Medicine, Northumbria Health Care Trust and<br />

University of Newcastle upon Tyne, United Kingdom<br />

7 Stop Stroke. A new intervention to improve stroke secondary<br />

prevention<br />

J. Redfern, C. McKevitt, A. Rudd, C. Wolfe, King's College London,<br />

United Kingdom<br />

8 Thrombolytic therapy for acute ischemic stroke: the SYNTHESIS trial<br />

A. Ciccone, E. Boccardi, C. Coppola, A. Gatti, A. Guccione, I. Santilli,<br />

L. Valvassori, Dept. of N<strong>eu</strong>rosciences, A.O. Niguarda Ca' Granda, Italy


9 Controlling Hypertension and Hypotension Immediately Post-Stroke<br />

(CHHIPS) Trial<br />

T.G. Robinson, J.F. Potter, G.A. Ford, CHHIPS Trial Group, Leicester Warwick<br />

Medical School, United Kingdom<br />

10 The Ongoing Telmisartan Alone and in combination with Ramipril<br />

Global Endpoint Trial (ONTARGET) in 25,000 patients at high risk of<br />

stroke and cardiovascular disease: recruitment update<br />

A.C.S. Anderson, University of Auckland, New Zealand<br />

11 ESPRIT: mild anticoagulation, acetylsalicylic acid plus dipyridamole<br />

or acetylsalicylic acid alone after cerebral ischemia of arterial origin<br />

E. De Schryver, C. Ferrier, ESPRIT Study Group, University Medical Center<br />

Utrecht, The Netherlands<br />

12 Magnesium and Acetylsalicylic Acid in Subarachnoid Hemorrhage<br />

(MASH), a prospective randomised, placebo-controlled, multicenter<br />

trial<br />

W. van den Bergh, G. Rinkel, MASH Study Group, Department of<br />

N<strong>eu</strong>rosurgery, University Medical Centre Utrecht, The Netherlands<br />

13 Clinical value of motor imagery and bodyweight supported treadmill<br />

training for recovery of gait performance of stroke patients in the<br />

early phase<br />

S. Borsje, J.B.H. Hochstenbach, K. Postema, T. Mulder, University Hospital<br />

Groningen, The Netherlands<br />

14 The European PFO Data Registry (EUROPFORE)<br />

M.G. Hennerici, European PFO Data Registry, Dept. of N<strong>eu</strong>rology,<br />

Klinikum Mannheim, RFK University Heidelberg, Germany<br />

15 Motivational interviewing: altering outcome after stroke<br />

C. Sutton, H. Dickinson, M. Leathley, K. Hills, M. Auton, E. Lightbody,<br />

H. Gardner, C. Jack, M. van den Broek, C. Watkins, University of Central<br />

Lancashire, United Kingdom<br />

103


Poster Sessions Friday, May 23, 2003<br />

104<br />

16 PC-Trial – Patent Foramen Ovale and Cryptogenic Embolism<br />

H.P. Mattle, B. Meier, S. Windecker, PC-Trial Study Group, Inselspital,<br />

Switzerland<br />

17 Safe Implementation of Thrombolysis in Stroke – Monitoring Study<br />

(SITS-MOST)<br />

N.G. Wahlgren, A. Davalos, C. Fieschi, M. Grond, W. Hacke, M. Kaste,<br />

V. Larrue, K.R. Lees, Karolinska Hospital, Sweden<br />

18 The CICA Study<br />

J. Castillo, J. Matías-Guiu, E. Díez-Tejedor, E. Martínez Vila, CICA Study,<br />

Hospital Clínico Universitario de Santiago de Compostela, Spain<br />

19 Prevention Regimen For Effectively avoiding Second Strokes<br />

(PRoFESS): rationale and design<br />

H.C. Diener, PRoFESS Collaborative Group, University of Essen, Germany<br />

20 Age-related white matter changes are correlated with gait<br />

disturbances in cross-section analysis – preliminary results of the<br />

LADIS (l<strong>eu</strong>koaraiosis and disability) project<br />

H. Baezner, C. Blahak, M.G. Hennerici, J. Bogousslavsky, D. Inzitari, LADIS<br />

Study Group, Department of N<strong>eu</strong>rology, Mannheim University Hospital,<br />

Heidelberg University, Germany<br />

21 Basilar Artery International Cooperation Study (BASICS)<br />

W.J. Schonewille, A. Algra, L.J. Kappelle, C.A. Molina, C.A. Wijman,<br />

University Medical Center Utrecht, The Netherlands<br />

22 Aortic Arch Related Cerebral Hazard (ARCH)<br />

G.A. Donnan, ARCH Steering Committees, National Stroke Research Institute,<br />

Australia<br />

23 Stroke patients in rehabilitation<br />

J.A. Mirallas, A. Beltrán, T. Ricarte, F. Torralba, C. Trenor, A. Soler,<br />

Stroke patients cost in Rehabilitatión, Hospital General de Castellón, Spain<br />

24 Efficacy of nitric oxide in stroke (ENOS) trial – a prospective<br />

randomised controlled trial in acute stroke<br />

P.M. Bath, ENOS Investigators, Nottingham University, United Kingdom


25 FOOD (Feed Or Ordinary Diet): a “family” of three randomised trials<br />

evaluating feeding policies for patients admitted to hospital with a<br />

recent stroke<br />

M.S. Dennis, International Stroke Trials (IST) Collaboration – FOOD,<br />

University of Edinburgh, United Kingdom<br />

26 CLOTS (Clots in Legs or TEDS after Stroke). A randomised trial to<br />

establish the effectiveness of graduated compression stockings to<br />

prevent post stroke deep vein thrombosis (DVT)<br />

A.M.S. Dennis, University of Edinburgh, Dept. of Clinical N<strong>eu</strong>rosciences,<br />

Western General Hospital, Edinburgh, United Kingdom<br />

27 The correlation between TCD findings and cerebral angiography with<br />

percutaneous transluminal balloon angioplasty in the stenotic middle<br />

cerebral artery<br />

K.H. Cho, B.C. Kim, M.K. Kim, J.J. Seo, J.K. Kim, K.H. Cho, Department of<br />

N<strong>eu</strong>rology and Diagnostic Radiology, Chonnam National University Medical<br />

School, South Korea<br />

28 The International Carotid Stenting Study<br />

M.M. Brown, R.L. Featherstone, The National Hospital for N<strong>eu</strong>rology and<br />

N<strong>eu</strong>rosurgery, United Kingdom<br />

29 Perfusion-CT guided intravenous thrombolysis after<br />

3 to 6 hours: Feasability and safety study<br />

P. Michel, M. Wintermark, M. Reichhart, F. Vingerhoets, R. M<strong>eu</strong>li,<br />

J. Bogousslavsky, Centre Hospitalier Universitaire Vaudois, Switzerland<br />

105


Instructions for Authors<br />

Oral Presentations<br />

All lecture rooms are equipped with a PC and a data projector for PowerPoint presentations.<br />

The use of laptops in the lecture rooms is not possible.<br />

PowerPoint presentations must be handed in via floppy disk, CD-ROM, zip drive or via your<br />

own laptop at the Speakers Service Centre (SSC).<br />

It is essential for the smooth running of the conference that all speakers hand in their<br />

presentations at least one hour before the beginning of their lectures. Speakers will<br />

have the opportunity to review their presentations on PCs available in the SSC.<br />

The SSC is located on the ground floor of the conference centre, between Auditorium I and<br />

Auditorium II.<br />

106


Poster Presentations<br />

Please note the following times for the presentation of your poster as well as for set-up<br />

and removal:<br />

Date of Session Preview Presentation Mounting Removal<br />

session No. time time time time<br />

Thursday, I 13.00– 16.00– 08.00– 18.00–<br />

May 22 14.30 h 17.30 h 09.00 h 19.00 h<br />

Friday, II 12.30– 16.00– 08.00– 18.00–<br />

May 23 14.00 h 17.30 h 09.00 h 19.00 h<br />

Authors are requested to be present at their posters during the presentation times<br />

mentioned above.<br />

Please note that the mounting and removal of the posters is in the responsibility of the<br />

authors. Posters that have not been removed by the authors after 19.00 h will be removed<br />

and disposed by the organisers.<br />

Publication<br />

All accepted abstracts are published in a supplement to Cerebrovascular Diseases and<br />

on a corresponding CD-ROM according to the submission rules. Abstract booklet<br />

and CD-ROM will be handed out to all registered participants at the registration desk.<br />

107


Welcome Reception<br />

Wednesday, May 21, 2003, as from 19.30 h<br />

Welcome Reception<br />

The Welcome Reception takes place in the stunning complex of cultural attractions known<br />

as the City of Arts and Sciences which lies at the southern tip of the riverbed garden.<br />

Eyeball-shaped L’Hemisfèric houses a planetarium, laserium, and IMAX theatre, and uses<br />

hydraulic lifts to make the building's eyelid open and close. L’Hemisfèric will host the<br />

participants of the 12 th European Stroke Conference for the Welcome Reception.<br />

The Welcome Reception is sponsored by Ferrer Group.<br />

108


Accompanying Persons Programme<br />

Wednesday, May 21, 2003, 9.30–17.30 h<br />

Requena<br />

The city of Requena is located in the region of 'Plana de Utiel-Requena' in the province of<br />

Valencia, renown for its monuments as well as its wine and sausage production.<br />

We shall visit the district of ‘La Villa’, which was declared an Artistic-Historical National<br />

Monument in 1966; the ‘Caves of La Villa’, which served as food warehouses, wine cellars<br />

and refuge during various war periods; the Santa Maria Church, which was declared a<br />

National Monument in 1931; as well as the wine cellar ‘Mas de Bazan’, which produces<br />

excellent red and rosé wines.<br />

Enjoy lunch in a typical local restaurant with wine, mineral water and coffee included.<br />

In the afternoon we will visit the ‘Esther Mill’ located in Requena city. This grain mill dating<br />

back to the 16 th century is the last functioning mill in Spain with hydraulic power.<br />

On the way back to Valencia we will stop in ‘El Rebollar Natural Park’ which is well-known<br />

for its great variety of Iberian peninsula fauna, from big Iberian bears to the small ‘gineta’.<br />

A demonstration of birds of prey will be given.<br />

Price / person: € 95<br />

Meeting: 9.15 h outside the main entrance of the Palacio de Congresos<br />

109


Accompanying Persons Programme<br />

Thursday, May 22, 2003, 9.30–13.00 h<br />

Valencia Sightseeing Tour Including the Historic Centre<br />

Enjoy the city panorama as well as an in depth exploration of the historical centre on foot.<br />

Delight in the charm of its streets, squares and hidden corners, discovering the Central<br />

Market, a modernist building, with its abundant display of typical regional produce.<br />

This tour will include visits to the Cathedral, the Miguelete Tower and the Lonja (declared<br />

Patrimony of Humanity by the UNESCO).<br />

Price / person: € 25<br />

Meeting: 9.15 h outside the main entrance of the Palacio de Congresos<br />

Friday, May 23, 2003, 9.30–13.30 h<br />

The City of the Arts and Sciences<br />

The City of the Arts and Sciences is an avant-garde construction for cultural and scientific<br />

activities. The area is composed of several buildings of striking architectural quality<br />

designed by Santiago Calatrava:<br />

• Umbracle: a promenade<br />

• Hemisferic: the only facility in Spain to project three audiovisual shows on a huge<br />

concave screen of 900 square metres<br />

• Mus<strong>eu</strong>m of the Sciences Principe Felipe: a science and technology mus<strong>eu</strong>m with<br />

state-of-the-art, interactive contents that makes Valencia an outstanding international<br />

landmark in the 21 st century<br />

• Palace of the Arts and Oceanografic: currently under construction<br />

Price / person: € 35<br />

Meeting: 9.15 h outside the main entrance of the Palacio de Congresos<br />

110


Saturday, May 24, 2003, 9.30 – 13.30 h<br />

Visit to the Albufera National Park<br />

Located 11 km south of the city and set between rice paddies and the sea, this area is<br />

closed off by the geological embrace of the mouths of the Turia and Jucar Rivers.<br />

The Albufera Natural Park is a paradise for migratory birds and a recreational area for<br />

the city and its surrounding municipalities. We shall visit the following:<br />

• The lookout point of the lake located next to the first lock on the 'El Saler' Road<br />

• Raco de L’Olla Centre, an informative area with panels and audiovisuals about the<br />

Albufera<br />

• Interpretation area, for a closer look at the park's ecosystem<br />

• Boat rides and optional lunch on the island of El Palmar, a quaint village closely<br />

connected to the fishing trade<br />

Price / person: € 40 (lunch not included)<br />

Meeting: 9.15 h outside the main entrance of the Palacio de Congresos<br />

General Remark<br />

All tours are based on a minimum of 25 participants. If a tour does not take place due<br />

to an insufficient number of participants, the ticket will be reimbursed in full. Otherwise<br />

please note that tickets for excursions are non-refundable.<br />

111


General Information (in alphabetical order)<br />

Abstract Book<br />

All accepted abstracts are published in a supplement to the journal Cerebrovascular<br />

Diseases according to the submission rules. You will find a copy in your congress bag.<br />

Badges<br />

Access to all scientific sessions and to the exhibition is only possible with your personal<br />

badge. All participants are requested to wear their name badges throughout the conference.<br />

€ 20 will be charged for the replacement of a lost badge.<br />

Banks<br />

Banks are generally open from Monday to Friday from 8.30 or 9.00 h to 14.00 or 14.30 h.<br />

Some banks open certain afternoons in the week. Almost every bank has a 24-hour cash<br />

machine.<br />

Cancellation / Refund Policy<br />

Refund of registration fees, less 25% administrative charges, could have been applied for in<br />

writing to the Administrative Secretariat until April 10, 2003. After this date no refund will be<br />

possible.<br />

Climate<br />

At the end of May the climate is usually very pleasant with temperatures around 20 °C<br />

during the day.<br />

Correspondence after the Congress<br />

ESC 2003 Phone +41 61 686 77 11<br />

c/o AKM Congress Service Fax +41 61 686 77 88<br />

PO Box E-mail info@akm.ch<br />

Clarastrasse 57<br />

CH-4005 Basel, Switzerland<br />

112


Currency<br />

The official currency in Spain is Euro (€). All congress prices are indicated in Euro.<br />

All major credit cards are accepted in most hotels, restaurants and shops.<br />

Electricity<br />

The electrical power supply in Spain has 220 Volt (European standard plug).<br />

Exhibition<br />

An industrial exhibition takes place during the conference. Please also refer to the<br />

exhibitors list on page 119.<br />

Hotel Accommodation<br />

AKM Travel is present at the Hotel Desk located in the registration area.<br />

Insurance<br />

The congress organisers cannot accept liability for personal injuries sustained, or for loss or<br />

damage of property belonging to congress participants (or their accompanying persons),<br />

either during or as a result of the congress. Please check the validity of your own insurance.<br />

Internet Corner<br />

Several Internet terminals are located in the exhibition area and are available to all<br />

conference participants.<br />

Language<br />

The congress language is English. Simultaneous translation is not provided.<br />

Mobile Phones<br />

Please note that mobile phones must be switched off during all sessions.<br />

113


General Information (in alphabetical order)<br />

Opening Hours of the Conference Secretariat<br />

The Conference Secretariat and Registration Desk at the Palacio de Congresos will be open<br />

during the following hours:<br />

Wednesday, May 21, 2003 12.00 – 18.00 h<br />

Thursday, May 22, 2003 07.30 – 18.30 h<br />

Friday, May 23, 2003 07.30 – 18.30 h<br />

Saturday, May 24, 2003 08.00 – 14.00 h<br />

Poster Exhibition / Poster Lunches<br />

The poster exhibition is located on the 2 nd floor of the conference centre. For detailed<br />

information on the poster sessions, please refer to pages 54–105.<br />

Lunch (fingerfood) will be offered to the participants during the poster preview times<br />

on Thursday and Friday in the restaurant on the 1 st floor.<br />

Press<br />

The press centre is located on the ground floor of the conference centre.<br />

On-Site Registration Fees<br />

Participants<br />

Junior delegates<br />

€ 600<br />

(born after 31.12.1969) * € 400<br />

Teaching Courses free<br />

Accompanying persons € 60<br />

* Proof required<br />

114


The fees for conference participants include:<br />

• Congress bag<br />

• Final Programme / Abstract Book<br />

• Admission to all scientific parts of the congress and the exhibition<br />

• Welcome Reception<br />

• Coffee breaks<br />

• Poster lunches<br />

The fees for accompanying persons include:<br />

• Welcome Reception<br />

• Valencia sightseeing tour<br />

Onsite registrants cannot be guaranteed to receive all congress documents.<br />

Restaurants<br />

Sun and oranges, delicious seafood, vegetables and very good wines (D.O. Utiel-Requena<br />

and Valencia) – those are the catchwords characterising one of the finest cuisines of Spain.<br />

Also rice, which is produced here in large quantities, is a protagonist in many typical dishes.<br />

The Valencianos understand to combine those ingredients to perfect masterpieces, Paella<br />

Valenciana being the most famous example.<br />

Shopping Hours<br />

Shops are generally open from 10.00–14.00 h and from 17.00–20.00 h, Mondays through<br />

Saturdays. Department stores and malls are usually open from 10.00–21.00 h and do not<br />

close during lunchtime.<br />

Time<br />

Spain is 1 hour ahead of Greenwich Mean Time (GMT).<br />

115


General Information (in alphabetical order)<br />

Transportation Tickets<br />

Valencia is covered by an extensive public transportation network, including four metro<br />

lines and public buses which travel to any part of the city. Apart from the single tickets,<br />

which can be bought at the metro stations and on the buses, there also are 1-day and 3-day<br />

tickets available which are sold at the Hotel Desk at a price of € 6 and € 12 respectively.<br />

Valencia<br />

Valencia is a vibrant, cosmopolitan city on the Mediterranean coast. Once the capital of its<br />

own kingdom, it now is a regional capital and Spain’s third largest city. Surrounded by<br />

immense orange orchards and sandy beaches, the city enjoys year-round sunshine and has<br />

become a popular business centre.<br />

The city was founded by the Romans, taken by the Visigoths, and prospered under the<br />

Moors. Each civilisation has left its mark: The historic centre includes a 13 th century<br />

cathedral (La Seo) with paintings by Goya and a splendid gothic 15 th century silk exchange<br />

(La Lonja). However, the city is looking to the future and is now home to one of Europe’s most<br />

exciting urban development projects. Some USD 200 million has been invested in building<br />

the immense and futuristic City of the Arts and Sciences (Ciutat de les Arts i les Ciencies)<br />

which is located near the port.<br />

Valencia means commerce and culture, cinema, theatre, mus<strong>eu</strong>ms, music and business.<br />

It is a centre for industrial design and avant-garde movements. Valencia is a city that never<br />

sleeps, with an extensive cultural line-up.<br />

During your stay in Valencia, you will also be able to enjoy the peace and quietness of<br />

several exceptional natural sites. Between the sea and the rice paddies, closed in by two<br />

river mouths, the Albufera Natural Park is a paradise for migratory birds and a recreation<br />

area for the city. Along the coast next to the Albufera there are broad sandy beaches.<br />

Venue<br />

Palacio de Congresos<br />

Avda. Cortes Valencianas, 60<br />

E-46015 Valencia, Spain<br />

The Palacio de Congresos is built by the world famous architect Norman Foster and an<br />

experience of its own.<br />

116


Notes<br />

117


Conference Venue Overview<br />

2 nd Floor<br />

Poster Exhibition<br />

1 st Floor<br />

Committee Rooms (Teaching Courses / Meetings)<br />

Poster Lunches<br />

Ground Floor<br />

Auditorium I, II and III<br />

Speakers Service Centre SSC<br />

Exhibition<br />

Internet Corner<br />

Registration / Secretariat / Hotel Desk<br />

Press Room<br />

Cafeteria / Cash Bar<br />

118


List of Exhibitors (in alphabetical order)<br />

127 5th World Stroke Congress, Vancouver / Canada<br />

125 Bayer HealthCare, Leverkusen / Germany<br />

103 Bioscience Ediprint Inc., Geneva / Switzerland<br />

113 Boehringer Ingelheim, Ingelheim / Germany<br />

126 Cerebricon Ltd., Kuopio / Finland<br />

131 DWL Elektronische Systeme GmbH, Sipplingen / Germany<br />

102 European Association of Young N<strong>eu</strong>rologists Trainees – EAYNT<br />

107 European Federation of N<strong>eu</strong>rological Associations – EFNA, Vienna / Austria<br />

107 European Federation of N<strong>eu</strong>rological Societies – EFNS, Vienna / Austria<br />

106 European Stroke Initiative – EUSI, Helsinki / Finland<br />

105 Ferrer Group, Barcelona / Spain<br />

101 Grupo Uriach, Barcelona / Spain<br />

133 MSD, Madrid / Spain<br />

121 NMT Medical Inc., Boston MA / USA<br />

129 Novo Nordisk, Bagsvaerd / Denmark<br />

109 S. Karger AG, Basel / Switzerland<br />

111 Sanofi-Synthélabo / Bristol-Myers Squibb, Paris / France<br />

123 SITS International, Stockholm / Sweden<br />

Bookdisplay<br />

Wisepress Bookshop, London / United Kingdom<br />

119


Exhibition and Conference Venue Plan<br />

120<br />

Cash<br />

Bar<br />

101<br />

103<br />

102<br />

105<br />

106<br />

109<br />

107<br />

Auditorium I<br />

111<br />

113


Speakers<br />

Service<br />

Centre<br />

121 123<br />

121 123<br />

125<br />

126<br />

Auditorium II<br />

127<br />

129<br />

131<br />

133<br />

Auditorium III<br />

121


Valencia Sights<br />

122


1. City HalI <br />

2. Flower Market<br />

3. Post Office<br />

4. Main Theatre <br />

5. Bullfighting Mus<strong>eu</strong>m<br />

6. Bullring<br />

7. Train Station <br />

8. St Augustine Church<br />

9. Cultural Centre. Former Hospital<br />

for the Poor<br />

10. Santa Lucia Chapel<br />

11. Craftsmanship Centre<br />

12. Church of the Pilar<br />

13. St Sebastian Parochial Church<br />

14. Quart Towers<br />

15. Botanical Gardens<br />

16. La Beneficencia Cultural Centre<br />

17. Marquis de Campo Asylum<br />

18. Valencian Institute of Modern Art<br />

19. Jose Benlliure Home Mus<strong>eu</strong>m<br />

20. El Carmen Church<br />

21. El Carmen Art Centre<br />

22. La Pineda Palace<br />

23. Puente de Madera Station<br />

(Trams to beaches)<br />

24. Turia Gardens<br />

25. San Pio V Fine Arts Mus<strong>eu</strong>m<br />

26. Royal Gardens or Los Viveros<br />

27. Monforte Gardens<br />

28. Paseo de la Almeda<br />

29. Serranos Towers<br />

30. Casa de las Rocas<br />

31. Valldigna Portal<br />

32. Church of St Nicholas<br />

33. Benicarlo Palace. Seat of the<br />

Valencian Parliament<br />

34. Baylia Palace. Seat of the<br />

Provincial Council<br />

35. Marques de Scala Palace<br />

36. Palau de la Generalitat<br />

37. Basilica of Our Lady of the<br />

Forsaken<br />

38. Cathedral complex:<br />

Cathedral, Miguelete Tower,<br />

Holy Grail Chapel<br />

39. Archbishop's Palace<br />

40. Crypt of St Vicente the Martyr<br />

41. Marquis de Campo Palace.<br />

City Mus<strong>eu</strong>m<br />

42. Royal Monastery of the Trinity<br />

43. Almudin (13 th century city<br />

granary)<br />

44. <strong>Esc</strong>riva Palace<br />

45. Church of St John of the Hospital<br />

46. St Thomas and San Felipe Neri<br />

Church<br />

47. Former Santo Domingo Convent.<br />

Levante Regional Military Govt.<br />

48. Civil Government<br />

49. Church of the Temple<br />

50. Birthplace of San Vicente Ferrer<br />

51. Tourist Office, Cal le Paz<br />

52. La Glorieta Gardens<br />

53. Courthouse<br />

54. Parterre Gardens<br />

55. Patriarch's Seminary<br />

56. Old University of Valencia<br />

57. Church of St John of the Cross<br />

58. Palace of the Marquis of Dos<br />

Aguas. Gonzalez Martií National<br />

Ceramics Mus<strong>eu</strong>m<br />

59. St Martin’s Church<br />

60. Plaza Redonda<br />

61. Church and Belltower of<br />

St Catherine<br />

62. The Silk Exchange and Maritime<br />

Consulate (World Heritage)<br />

63. The Central Market<br />

64. Santos Juanes Church<br />

123


Notes


Notes


Notes


Notes


Notes<br />

Printed in Switzerland A15668 IR.04.2003/3.0

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