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(eshi) diploma - BDC

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5. Transplant immunology<br />

Knows and understands the physiological processes and the clinical relevance of the<br />

following in relation to H&I services:<br />

a. Direct and indirect T cell activation<br />

b. Role of passenger leukocytes<br />

c. Immune processes leading to hyperacute, acute, accelerated and chronic<br />

allograft rejection<br />

d. Immune processes leading to GvHD<br />

e. GvL<br />

f. Relevance of HLA antibodies in rejection<br />

g. Non-HLA immunity<br />

h. Tolerance and regulatory cell populations<br />

i. NK cells in rejection and GvHD/GvL<br />

j. Minor histocompatibility antigens<br />

k. Non inherited maternal antigens (NIMA)<br />

Evidence Date Trainee Signature Trainer Signature<br />

Page 14 of 25

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