Development of safe and immunogenic reassortant viruses with 5:3 ...
Development of safe and immunogenic reassortant viruses with 5:3 ...
Development of safe and immunogenic reassortant viruses with 5:3 ...
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Mutations in internal genes <strong>of</strong> MDV<br />
A/Leningrad/134/17/57 (H2N2)<br />
PB2<br />
PB1<br />
PA<br />
NP<br />
M<br />
NS<br />
Master Donor Virus<br />
A/Leningrad/134/17/57 (H2N2)<br />
Val-478-Leu<br />
Lys-265-Asn;<br />
Val-591-Ile<br />
Leu-28-Pro;<br />
Val-341-Leu<br />
none (egg-grown);<br />
Asn-492-Ser (MDCK-grown)<br />
Ile-15-Val (M1);<br />
Phe-144-Leu (M1)<br />
Met-100-Ile (NS2)<br />
Unique mutations for MDV<br />
5 <strong>of</strong> 16
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