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Ludiflash - Pharma Ingredients & Services BASF

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Example application:<br />

Risperidone formulation with <strong>Ludiflash</strong> ®<br />

With <strong>Ludiflash</strong> ® , the Risperidone formulation exhibits a hardness of 56 N<br />

(10 mm round, flat tablets) and an extraordinarily low friability of less than<br />

0.1 % at a compression force of only 4 kN.<br />

The disintegration time is less than 30 seconds and 98 % of the active<br />

ingredient is dissolved within just 5 minutes.<br />

dissolution rate [%]<br />

120<br />

100<br />

80<br />

60<br />

40<br />

20<br />

0<br />

0 2 4 6 8 10 12 14 16<br />

time [min.]<br />

8

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