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PATHOGENESIS OF BACTERIAL INFECTION - LF

PATHOGENESIS OF BACTERIAL INFECTION - LF

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Enzymes<br />

Many species of bacteria produce enzymes that are not<br />

intrinsically toxic but play important role in the infectious<br />

process.<br />

Collagenase<br />

– degrades collagen, the major protein of fibrous<br />

connective tissue, and promotes spread of infection in<br />

tissue.<br />

Coagulase<br />

– Staphylococccus aureus produce coagulase, which<br />

works in conjuction with serum factors to coagulate<br />

plasma. Coagulase contributes to the formation of fibrin<br />

walls around staphylococcal lesions, which helps them<br />

persist in tissues.

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