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Health & Wellness | Looking Great<br />

Health<br />

&<br />

Wellness<br />

Why Won’t My<br />

“Sun Spots”<br />

Go Away?<br />

By Dr. Kimberly Moskowitz<br />

The Heartache <strong>of</strong><br />

Melasma<br />

Melasma, derived from the<br />

Greek word Melas, meaning<br />

“black,” appears as symmetrical<br />

irregular patches <strong>of</strong> tan or<br />

brown pigmentation on sun<br />

exposed areas <strong>of</strong> the face such<br />

as the cheeks, forehead, upper<br />

lip, and chin. <strong>This</strong> confidence<br />

crushing skin condition is nine<br />

times more common in women<br />

than men and affects more<br />

than five million people in the<br />

United States alone. There<br />

are few things women enjoy<br />

more than being able to roll<br />

out <strong>of</strong> bed in the morning with<br />

youthful flawless skin. Irregular<br />

pigmentation on the face is one<br />

<strong>of</strong> the earliest signs <strong>of</strong> aging<br />

skin and it <strong>of</strong>ten makes people<br />

appear older than they are.<br />

Melasma is <strong>of</strong>ten associated<br />

with Moms-to-be as it is notoriously<br />

known as the “mask <strong>of</strong><br />

pregnancy.” Although the majority<br />

<strong>of</strong> patients with melasma<br />

are not pregnant, it tends to<br />

creep onto our skin during the<br />

reproductive years, and <strong>of</strong>ten<br />

coincides with the mainstream<br />

panic over fine lines, wrinkles,<br />

age spots and gravity. Melasma<br />

can also develop with oral<br />

contraceptive use or hormone<br />

replacement therapy. There is<br />

a strong genetic predilection<br />

for darker skin types such as<br />

Mediterranean, Hispanic, and<br />

Asian populations but to date,<br />

there is no single known cause<br />

<strong>of</strong> melasma.<br />

Aside from genetics, the most<br />

important factor in the development<br />

<strong>of</strong> melasma is exposure<br />

to the ultraviolet rays <strong>of</strong><br />

the sun. The paradox <strong>of</strong> living<br />

in Florida is that our beautiful<br />

Gulf <strong>of</strong> Mexico provides a<br />

subtropical petri dish for many<br />

frustrating skin conditions such<br />

as sunspots, skin cancer, premature<br />

aging, and melasma.<br />

Melanocytes, the pigment<br />

producing cells in the skin, are<br />

stimulated by the sun’s UV rays<br />

to overproduce melanin. Like<br />

a callous, this is the skin’s way<br />

<strong>of</strong> protecting or shielding the<br />

deeper layers from injury. <strong>This</strong><br />

protective mechanism can<br />

manifest as a suntan, a freckle,<br />

an “age spot” or melasma.<br />

Sun exposure, hormones,<br />

pregnancy, skin trauma and<br />

some phototoxic drugs cause<br />

our melanocytes to become<br />

overactive, resulting in splotchy<br />

deposits <strong>of</strong> excess pigment in<br />

the dermis and epidermis.<br />

Daily application <strong>of</strong> broad<br />

spectrum UVA- UVB – protective<br />

sunscreen with an SPF <strong>of</strong> at<br />

least 30, containing Zinc Oxide<br />

or Titanium Dioxide is essential<br />

for long-term success in treating<br />

melasma and all pigmentary<br />

disorders. Without strict<br />

avoidance <strong>of</strong> sunlight, and daily<br />

application <strong>of</strong> sunscreen, potentially<br />

successful treatments<br />

for melasma are doomed to fail.<br />

While Melasma is physically<br />

harmless, it is <strong>of</strong>ten emotionally<br />

damaging and embarrassing.<br />

Fewer than 10% <strong>of</strong> patients<br />

will have remission <strong>of</strong> melasma<br />

without treatment.<br />

Hydroquinone aka “bleaching<br />

cream” has been used to treat<br />

disorders <strong>of</strong> hyperpigmentation<br />

for more than 50 years. Hydroquinone<br />

doesn’t really “bleach”<br />

your skin. Instead, it interrupts<br />

the abnormal pigment production<br />

by melanocytes, making<br />

your skin more uniform in color.<br />

Alone, Hydroquinone 4% cream<br />

clears melasma in 35-40% <strong>of</strong><br />

patients. Prescription regimens<br />

combining glycolic acid,<br />

daily use <strong>of</strong> a broad spectrum<br />

sunscreen, and “triple cream”<br />

(Hydroquinone 4%, Retinoic<br />

Acid 0.05-0.1%, flourinated<br />

steroid cream), clears melasma<br />

in 85-90% <strong>of</strong> patients within 3-6<br />

months.<br />

Beware <strong>of</strong> over-the-counter<br />

preparations and those found<br />

in shopping networks, magazine<br />

ads, and cosmetic counters<br />

that convincingly promise<br />

miracles yet cause you to lose<br />

precious time and money.<br />

They have little to no benefit<br />

in treating melasma. A variety<br />

<strong>of</strong> “natural” ingredients may<br />

help slow pigment production<br />

such as Azeleic Acid,<br />

Kojic Acid, and L-ascorbic acid<br />

(Vitamin C); however, none<br />

have been shown to approach<br />

the effectiveness <strong>of</strong> the “triple<br />

cream.” Melasma is stubborn<br />

and even prescription strength<br />

creams may take as long as<br />

3-6 months to show improvement,<br />

and possibly a lifetime to<br />

maintain it. Deeper variants <strong>of</strong><br />

melasma are invariably frustrating<br />

because topical regimens<br />

do not penetrate far enough<br />

into the dermis to eradicate the<br />

pigment.<br />

Any discussion about treating<br />

pigmentary skin disorders<br />

would be incomplete without<br />

a mention <strong>of</strong> Laser treatments.<br />

Fraxel has catapulted laser<br />

technology into a resurfacing<br />

revolution with the treatment <strong>of</strong><br />

wrinkles, sagging skin, droopy<br />

eyes, sun damage, stretch<br />

marks, pre-cancerous lesions<br />

and melasma. Rather than<br />

leave millions <strong>of</strong> faces hidden<br />

behind a mask, patients are<br />

turning to Fraxel skin resurfacing,<br />

which shows a 74-100%<br />

clearance rate for abnormal<br />

pigmentation including melasma.<br />

Fraxel sends microscopic<br />

thermal wounds through the<br />

skin’s surface to break up the<br />

abnormal pigment and destroy<br />

over-producing melanocytes.<br />

Fraxel Restore and Fraxel <br />

Dual 1927 lasers have shown<br />

the most promise for those<br />

requiring immediate gratification;<br />

however, results still must<br />

be maintained with diligent sun<br />

protection and triple therapy<br />

to minimize the inflammatory<br />

response.<br />

Establishing realistic expectations<br />

is paramount to avoiding<br />

a lifetime <strong>of</strong> exasperation trying<br />

to cure a disorder that we<br />

can control but <strong>of</strong>ten cannot<br />

cure. If the curse <strong>of</strong> melasma is<br />

casting dark shadows on your<br />

face don’t allow it to conceal<br />

your beauty forever and never<br />

underestimate the tenacity <strong>of</strong><br />

this masked marauder. You<br />

can conquer melasma with a<br />

single Fraxel treatment and<br />

by taking simple daily steps<br />

(Sunscreen and triple cream) to<br />

unmask the radiant skin that is<br />

already yours.<br />

THE CIRCUIT September/October 2012 17

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