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HIV infectie - Itg

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Progressive Multifocal<br />

Leucoencephalopathy (PML)<br />

‣ JC virus<br />

‣ Sympt : insidious (no<br />

fever, no headache, no<br />

ICH)<br />

- Motor :Hemiparesis:<br />

Hemiparesis, hemiplegia<br />

- Visual : cortical blindness, hemianopsia dysarthria,<br />

- Cognitif : personality change, , dementia<br />

‣ Diagn: : CT Scan : multiple hypodense lesions<br />

of white matter, MRI, CSF: N (PCR: JC)<br />

‣ Prognosis : 6 M survival<br />

‣ Treatment = HAART<br />

‣ DD: lymphoma, toxo…

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