Thursday, June 23, 2011 63 Differential neuroanatomical correlates of adolescent and adult methamphetamine abuse I. Lyoo 1,2 , S. J. Yoon 3 , T. S. Kim 3 , J. Hwang 4 , J. E. Kim 1 , S. J. Bae 1 , D. J. Kim 1 , P. F. Renshaw 2 , 1 Department of Psychiatry, Seoul National University College of Medicine, Seoul, Republic of Korea, 2 Department of Psychiatry and The Brain Institute, University of Utah, Salt Lake City, UT, 3 Department of Psychiatry, Catholic University College of Medicine, Seoul, Republic of Korea, 4 Department of Psychiatry, Soonchunhyang University College of Medicine, Seoul, Republic of Korea 64 Investigating changes in fractional anisotropy in white matter of methamphetamine users using diffusion tensor imaging J. C. Lin 1,2 , R. K. Jan 1,2 , R. R. Kydd 3,2 , B. R. Russell 1,2 , 1 School of Pharmacy, The University of Auckland, Auckland, New Zealand, 2 Centre for Brain Research, The University of Auckland, Auckland, New Zealand, 3 Department of Psychological Medicine, The University of Auckland, Auckland, New Zealand 65 The effect of methamphetamine on grey matter structure in the human brain using voxel-based morphometry R. K. Jan 1,2 , J. C. Lin 1,2 , R. R. Kydd 3,2 , B. R. Russell 1,2 , 1 School of Pharmacy, University of Auckland, Auckland, New Zealand, 2 Centre for Brain Research, University of Auckland, Auckland, New Zealand, 3 Department for Psychological Medicine, University of Auckland, Auckland, New Zealand 66 Differentiating the association between cigarette smoking and methamphetamine use on gray matter abnormalities seen in methamphetamine abusers A. M. Morales 1,4 , B. Lee 2 , J. O’Neill 2 , E. London 2,3,4 , 1 Neuroscience Program, UCLA, Los Angeles, CA, 2 Psychiatry and Biobehavioral Sciences, UCLA, Los Angeles, CA, 3 Molecular and Medical Pharmacology, UCLA, Los Angeles, CA, 4 Brain Research Institute, UCLA, Los Angeles, CA 67 Reduced hippocampal volumes in regular cannabis users V. Lorenzetti 1 , N. Solowij 2 , A. Fornito 1 , D. Lubman 3 , M. Takagi 1 , C. Pantelis 1 , M. Seal 4 , M. Yucel 1 , 1 Psychiatry, Melbourne Neuropsychiatry Centre, East Brunswick, VIC, Australia, 2 Psychology, University of Wollongong, Wollongong, NSW, Australia, 3 Turning Point Alcohol and Drug Centre, Melbourne, VIC, Australia, 4 Murdoch Childrens Research Institute, Melbourne, VIC, Australia 68 Unexpected changes in striatal activation with treatment during the guess/reward fMRI task in comorbid MDD-CUD youth J. R. Cornelius 1 , H. Aizenstein 1 , T. Chung 1 , A. Douaihy 1 , I. Salloum 2 , D. Daley 1 , 1 Psychiatry, University of Pittsburgh, Pittsburgh, PA, 2 Psychiatry, University of Miami, Miami, FL 69 Brain activity related to decision-making among adolescents in substance abuse treatment S. R. Ryan, C. Stanger, A. Elton, Z. Gubrij, A. James, C. Kilts, W. Bickel, A. Budney, Psychiatric Research Institute, University of Arkansas for Medical Sciences, Little Rock, AR 70 Neuroimaging heavy cannabis users vs. sporadic and non-users: Working memory and decisionmaking A. E. Goudriaan 1 , J. Cousijn 1 , L. Porrino 2 , W. van den Brink 1 , D. J. Veltman 1 , R. W. Wiers 1 , 1 Dept. of Psychiatry, Academic Medical Centre, Amsterdam, Netherlands, 2 Physiology and Pharmacology, Wake Forest University, School of Medicine, Winston-Salem, NC 71 Nicotine effects on default mode and extra-striate resting state networks J. Tanabe, E. Nyberg, L. Martin, D. Cordes, E. Kronberg, J. Tregellas, University of Colorado Denver SOM, Aurora, CO 114
Thursday, June 23, 2011 72 Functional MRI-based support vector machine classification of tobacco smokers’ nicotine craving: Possible use in real-time neurofeedback Y. S. Shah 1 , S. J. Peltier 1 , L. Hernandez-Garcia 1 , D. C. Noll 1 , K. L. Phan 1 , J. K. Zubieta 1 , M. K. Greenwald 2 , 1 University of Michigan, Ann Arbor, MI, 2 Wayne State University, Detroit, MI 73 Anterior cingulate proton spectroscopy glutamate levels differ as a function of smoking cessation outcome Y. Mashhoon 1 , A. C. Janes 1 , J. E. Jensen 1 , A. P. Prescot 1 , G. Pachas 2 , P. F. Renshaw 1 , M. Fava 2 , A. E. Evins 2 , M. J. Kaufman 1 , 1 Neuroimaging Center, McLean Hospital | Harvard Medical School, Belmont, MA, 2 Massachusetts General Hospital | Harvard Medical School, Boston, MA 74 The effects of nicotine and non-nicotine components of cigarette smoking on cerebral blood flow M. Addicott 1 , R. Kozink 1 , T. Harshbarger 2 , B. Froeliger 1 , D. Ban 1 , J. Rose 1 , F. J. McClernon 1 , 1 Psychiatry, Duke Medical Center, Durham, NC, 2 Radiology, Duke Medical Center, Durham, NC GENETICS 75 Cocaine-induced changes in prefrontal cortex glutamate receptor expression depend upon Homer1 and Homer2 proteins A. W. Ary, B. W. Miller, C. L. McKenna, L. M. Smith, K. K. Szumlinski, Psychology, University of California, Santa Barbara, Santa Barbara, CA 76 Sway: A new genetic model for diminished cocaine-reinforced behavior K. Grasing 1 , S. He 1 , Y. Yang 1 , E. Bryda 2 , 1 Substance Abuse Research Laboratory, VA Medical Center, Kansas City, MO, 2 Veterinary Medicine, University of Missouri, Columbia, MO 77 Dopamine transporter, substance abuse, and sex differences in novelty-seeking R. Ashare 1 , C. Hodgkinson 2 , M. Enoch 2 , D. Goldman 2 , R. Sinha 1 , 1 Yale University, New Haven, CT, 2 LNG at NIAAA, Bethesda, MD 78 Compulsive drug-taking behavior: Interaction of specific genetic variants with response to cocaine vaccine on treatment effectiveness in cocaine dependence J. A. Lindsay, D. Nielsen, T. R. Kosten, Baylor College of Medicine, Houston, TX 79 Preliminary pharmacogenetic study of treatment for methamphetamine dependence K. G. Heinzerling, J. McCracken, L. Ray, A. Swanson, S. Shoptaw, UCLA, Los Angeles, CA 80 Genome-wide association study of addiction to smoking and other substances of abuse M. D. Li 1 , S. G. Yi 1 , J. Z. Ma 2 , 1 Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA, 2 Public Health Sciences, University of Virginia, Charlottesville, VA 81 ANKK1 polymorphisms may influence beta2-nicotinic acetylcholine receptor availability in nonsmokers K. Cosgrove 1 , B. Yang 1 , I. Esterlis 1 , D. Lee 1 , R. Gadsden 1 , S. Helmbrecht 1 , F. Bois 1 , J. Seibyl 2 , G. Tamagnan 2 , J. Staley 1 , J. Gelernter 1 , 1 Psychiatry, Yale University School of Medicine, New Haven, CT, 2 Institute for Neurodegenerative Disorders, New Haven, CT 82 Learning and memory differences in the dopamine receptor D2 Taq1A & C957T gene SNP among HIV-positive alcohol abusers P. Khatavkar 1 , V. Bryant 1 , M. José-Miguez Perez 1 , R. Malow 1 , B. Lerner 1 , J. Dévieux 1 , R. Rosenberg 1 , N. Gandhi 2 , M. Nair 2 , 1 Stempel College of Social Work and Public Health, Florida International University, North Miami, FL, 2 Immunology, Institute of Neuro-Immune Pharmacology, Florida International University, Miami, FL 115
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P R O G R A M 73rd Annual Scientifi
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PRE-MEETING SATELLITES NIDA: Fundam
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Sunday, June 19, 2011 Late-Breaking
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Sunday, June 19, 2011 Symposium I R
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Sunday, June 19, 2011 Oral Communic
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Monday, June 20, 2011 Poster Sessio
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Monday, June 20, 2011 20 Variabilit
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Monday, June 20, 2011 45 Residentia
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Monday, June 20, 2011 69 Prescripti
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Monday, June 20, 2011 93 Relationsh
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Monday, June 20, 2011 115 Adolescen
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Monday, June 20, 2011 140 Impulsive
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Monday, June 20, 2011 166 Use of ov
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Monday, June 20, 2011 Symposium IV
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Monday, June 20, 2011 2:45 The long
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Monday, June 20, 2011 3:15 Effects
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Monday, June 20, 2011 Workshop VIII
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Monday, June 20, 2011 Cognition Pro
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Monday, June 20, 2011 Knowledge of
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Monday, June 20, 2011 Utility and c
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Monday, June 20, 2011 Genetic and e
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Monday, June 20, 2011 Characteristi
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Monday, June 20, 2011 Differences i
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Monday, June 20, 2011 Family and ac
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Monday, June 20, 2011 Updated curri
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Monday, June 20, 2011 Evidence-base
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Monday, June 20, 2011 A case-contro
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Monday, June 20, 2011 University of
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Monday, June 20, 2011 Compulsory dr
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Tuesday, June 21, 2011 9 Developmen
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Tuesday, June 21, 2011 30 Recreatio
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Tuesday, June 21, 2011 53 Health co
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INRC INDEX Scarpini, E. 130 Scherre
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CPDD SYMPOSIA I. Prenatal cocaine e
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CPDD SYMPOSIA discuss NIDA's resear
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CPDD SYMPOSIA disorders in offsprin
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CPDD SYMPOSIA understand the molecu
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CPDD WORKSHOPS I. 17th Annual Conti
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CPDD WORKSHOPS important methodolog
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CPDD WORKSHOPS Analytical Services
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INRC SYMPOSIUM ABSTRACTS EPIGENETIC
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INRC SYMPOSIUM ABSTRACTS motor cort
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INRC SYMPOSIUM ABSTRACTS variations
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INRC SYMPOSIUM ABSTRACTS Although t
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INRC SYMPOSIUM ABSTRACTS naltrexone
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INRC SYMPOSIUM ABSTRACTS effect on
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INRC SYMPOSIUM ABSTRACTS responses
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INRC SYMPOSIUM ABSTRACTS and the pr
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INRC SYMPOSIUM ABSTRACTS National S
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INRC SYMPOSIUM ABSTRACTS raised the
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INRC SYMPOSIUM ABSTRACTS antiallody
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INRC SYMPOSIUM ABSTRACTS neuropepti
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INRC SYMPOSIUM ABSTRACTS context-de
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Notes
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PLENARY FRIDAY, JUNE 24 Transcripti
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Chromatin plasticity in addicted br
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efficacy. Of special interest has b
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vivo pharmacological profiles of N/
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administration of morphine into the
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the absence of dynorphin results in
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autoradiography and a DOR-GFP repor
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dysphoria in humans. The dynorphin/
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YOUNG INVESTIGATOR SYMPOSIUM: OPIOI
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ORAL SESSION THURSDAY, JUNE 23 Regu
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compared to rats given a myristoyla
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2002, 55, 847). An alanine scan was
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the length of agonist application s
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casomorphin-8 in milk and in plasma
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Investigation on DNA methylation st
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2.25gm, up to 8 hrs afterward; plas
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activity. Rats were sacrificed unde
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of the MOR/DOR heteromer in vivo ha
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increased capsaicin-induced TRPV1 a
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235959 may have anti-nociceptive ef
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Morphine tolerance, desensitization
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Mu-opioid receptor desensitization
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Differential KOR agonist-induced ac
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acid (PUFA) including DHA. However,
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Differences in opioid peptide level
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P60-DA05130 grant and the Carson Fa
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genotype for variants rs997917 and
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30min of BK pretreatment. Parallel
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methylated at low levels in the hum
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in African populations. Both of the
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with lentivirus encoding shRNA agai
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Sleep disturbances in a neuropathic
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Chronic voluntary alcohol drinking