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Tertiary Structure

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Haemoglobin<br />

• Haemoglobin is a globular protein with<br />

a prosthetic ‘iron’ group<br />

b<br />

a<br />

• In adults, hemoglobin is made up of 4<br />

polypeptides (2 a polypeptide chains<br />

and 2 b polypeptide chains)<br />

• Each polypeptide surrounds a prosthetic<br />

‘haem’ group<br />

Fe<br />

• Hydrophobic interactions between side<br />

groups pointing inwards maintain the<br />

structure<br />

• Hydrophilic side chains point outwards<br />

making it soluble<br />

a<br />

b<br />

Protein <strong>Structure</strong><br />

©1999 Timothy G. Standish

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