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Deep Brain Stimulation - Black Dog Institute

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Disorder<br />

Parkinson’s<br />

Disease<br />

<strong>Deep</strong> <strong>Brain</strong> <strong>Stimulation</strong><br />

Patients<br />

Treated<br />

30,000-40,000<br />

Chronic Pain 1500-2000<br />

Tremor 500-1000<br />

<strong>Deep</strong> <strong>Brain</strong> Targets<br />

Globus pallidus internus,<br />

Subthalamic nucleus<br />

Ventral posterior medial and lateral thalamic<br />

nuclei, periventricular and periaqueductal<br />

gray matter<br />

Ventralis intermedius thalamic nucleus,<br />

zona incerta<br />

Dystonia 300-500<br />

Globus pallidus internus<br />

Cluster Headache 30-50<br />

Posterior hypothalamus<br />

Epilepsy 20-50<br />

Anterior thalamic nucleus<br />

OCD 20-50<br />

Anterior limb of internal capsule<br />

Depression ~ 100<br />

Tourette’s<br />

Syndrome<br />

10-50<br />

SubCallosal Cingulate, Internal Capsule,<br />

Nucleus Accumbens<br />

Ventromedial thalamic nuclei, anterior limb<br />

of internal capsule, globus pallidus internus<br />

Modified from Pereira et al, 2007

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