Guidelines for Diagnosis & Treatment of Malaria in India - NVBDCP

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Guidelines for diagnosis and treatment of malaria Table 2. Primaquine for P. vivax (Daily Dosage for 14 days) Age in years Daily dosage No. of tablets (in mg base) (2.5 mg base) < 1 Nil Nil 1 – 4 2.5 1 5 – 8 5.0 2 9 – 14 10.0 4 15 & above 15.0 6 Note: Primaquine should be given for 14 days under supervision. Do not give Primaquine to pregnant women and infants and G6PD deficiency cases. Table 3. ACT (Artesunate + SP) dosage schedule for P. falciparum Age in years Number of tablets 1 st Day 2 nd Day 3 rd Day < 1 AS ½ ½ ½ SP ¼ Nil Nil 1 – 4 AS 1 1 1 SP 1 Nil Nil 5 – 8 AS 2 2 2 SP 1½ Nil Nil 9 – 14 AS 3 3 3 SP 2 Nil Nil 15 and above AS 4 4 4 SP 3 Nil Nil AS – Artesunate 50 mg, SP – Sulfadoxine 500 mg + Pyrimethamine 25 mg Table 4. Primaquine for P. falciparum (Single dose on Day 2) Age in years Dosage No. of tablets (in mg base) (7.5 mg base) < 1 Nil 0 1 – 4 7.5 1 5 – 8 15 2 9 – 14 30 4 15 & above 45 6 Note: Do not give Primaquine to pregnant women, infants and G6PD deficiency cases. 7
Guidelines for diagnosis and treatment of malaria spond and presents with following, he/she should be given alternative treatment. Early treatment failure (ETF): Development of danger signs or severe malaria on Day 1, 2 or 3, in the presence of parasitaemia; parasitaemia on Day 2 higher than on Day 0, irrespective of axillary temperature; parasitaemia on Day 3 with axillary temperature 37.5°C; and parasitaemia on Day 3 25% of count on Day 0. Late clinical failure (LCF): Development of danger signs or severe malaria in the presence of parasitaemia on any day between Day 4 and Day 28 (Day 42) in patients who did not previously meet any of the criteria of early treatment failure; and presence of parasitaemia on any day between Day 4 and Day 28 (Day 42) with axillary temperature 37.5°C in patients who did not previously meet any of the criteria of early treatment failure. Late parasitological failure (LPF): Presence of parasitaemia on any day between Day 7 and Day 28 with axillary tem-perature 3 mg/dl) • Jaundice (Serum Bilirubin >3 mg/dl) • Severe anaemia (Hb
Page 2 and 3: Preface M alaria is a major public
Page 4 and 5: Guidelines for diagnosis and treatm
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Guidelines for Diagnosis & Treatment of Malaria in India - NVBDCP

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