What happens to blood glucose overnight - Dr Pratik ... - Dafne

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• 5 pts with “unmanageable”

diabetes

• Treated with 3 -4 times /

day soluble insulin

• Recurrent DKA and SH

• Insulin dose reduces from

60-70 units down to 18-30

units

• 2 further pts, one who

came off insulin

“Hypoglycaemia begets

hyperglycaemia”

American Journal of Medicine; 1959

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• 5 pts with “unmanageable” diabetes • Treated with 3 -4 times / day soluble insulin • Recurrent DKA and SH • Insulin dose reduces from 60-70 units down to 18-30 units • 2 further pts, one who came off insulin “Hypoglycaemia begets hyperglycaemia” American Journal of Medicine; 1959

Reduced insulin levels as long acting insulin ran out were associated with high blood glucose levels

Page 1 and 2: What happens to blood glucose overn
Page 3 and 4: Effect of nocturnal hypoglycaemia
Page 5 and 6: Fasting hyperglycaemia Glucose ( mm
Page 7: Dawn Or Somogyi?? Breakfas t
Page 11 and 12: T1DM Normal Diabetes, 2003
Page 13 and 14: Much of the variability in fasting
Page 15 and 16: Contd…. • Night time hypos were
Page 17 and 18: Summary • Nocturnal hypoglycaemia
Page 19: Relationship of fasting and nadir g

What happens to blood glucose overnight - Dr Pratik ... - Dafne

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