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The COEfficient The COEfficient - Capital Health

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FEATURE<br />

Miniaturizing tools for tots<br />

Physician-designed<br />

infant catheter<br />

finds open market<br />

Dr.Yashu Coe,<br />

pediatric interventional cardiologist at the Stollery Children’s<br />

Hospital, says the mortality rate for the treatment of defective<br />

heart valves in infants is now zero per cent. “Here at the Stollery,<br />

we’ve never had a procedural or late mortality.”<br />

Each year, the Stollery Children’s<br />

Hospital treats five to 10 infants for<br />

aortic stenosis (a narrowed aortic valve),<br />

one of eight common abnormalities that<br />

account for approximately 80 per cent<br />

of congenital heart defects.<br />

At one time, surgery was the treatment<br />

of choice. <strong>The</strong>n, 10 to 20 years ago,<br />

angioplasty offered an alternative.<br />

This procedure involves inserting<br />

and guiding a catheter into the heart<br />

through either a vein or an artery and<br />

inflating a balloon across the valve to<br />

eliminate the severely narrow valve<br />

opening. When he first began using<br />

Adult catheter (left) guide wire is<br />

0.035 inches compared with the infant<br />

catheter (right) at 0.018 of an inch.<br />

<strong>The</strong> infant catheter is more flexible<br />

and slimmer, allowing for easier<br />

navigation through the heart.<br />

this procedure, Dr. Coe found the<br />

balloon too fragile or the catheter<br />

too big for tiny babies’ bodies, and<br />

was determined to find a solution<br />

to improve the treatment for these<br />

critically sick infants.<br />

After conducting initial research,<br />

Dr. Coe, also a Professor of Pediatrics at<br />

the University of Alberta, approached<br />

various manufacturers to help him<br />

custom design a catheter to his specifications.<br />

When he finally discovered<br />

NuMed, a U.S. manufacturer with<br />

a facility in Canada, within a month,<br />

Dr. Coe had in hand his tot-specific<br />

catheter for angioplasty operations.<br />

“What’s neat about this is that it’s small;<br />

and the balloon – it’s very, very strong.”<br />

<strong>The</strong> <strong>COEfficient</strong>, as the tool is named,<br />

has since saved the lives of many infants.<br />

<strong>The</strong> catheter is now also used to<br />

correct severely malfunctioning<br />

pulmonary valves in newborns,<br />

at times a life-threatening condition<br />

that must be addressed immediately.<br />

Angioplasty operations come with the<br />

additional blessing that “the baby can<br />

usually go home sooner,” says Dr. Coe,<br />

unlike the longer recovery period<br />

required for more invasive surgery.<br />

With its new U.S. Food and Drug<br />

Administration’s stamp of approval,<br />

the <strong>COEfficient</strong> is ready for the open<br />

market. Until recently it was little known.<br />

In fact, not long ago in Germany,<br />

a delighted Dr. Coe impressed staff<br />

at a hospital he was visiting when<br />

they proudly revealed their “new”<br />

infant catheter – then discovered<br />

the design was his.<br />

LAUGHING DOG PHOTOGRAPHY<br />

www.capitalhealth.ca SUMMER 2006 ~ CHQ 7

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