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Bringing Scientific Innovation<br />

to Veterans Health<br />

Colon cancer is among the most preventable<br />

<strong>of</strong> cancers. Unlike lung cancer or breast cancer<br />

screening, which look for cancerous tumors, colon<br />

cancer screening looks for precursor lesions that can<br />

be removed before they become cancerous. “The<br />

problem,” says SFVAMC Chief <strong>of</strong> Radiology Judy<br />

Yee, MD, “is that only 40 percent <strong>of</strong> Americans<br />

who should be screened for colon cancer actually<br />

get screened.”<br />

Dr. Yee can understand why: current conventional<br />

screening methods such as colonoscopy are<br />

considered invasive and uncomfortable. Fortunately,<br />

Dr. Yee can <strong>of</strong>fer Veterans a less invasive alternative:<br />

virtual colonoscopy, which uses x-ray technology to<br />

create a complete three-dimensional picture <strong>of</strong> the<br />

entire colon in just minutes. “We’ve demonstrated<br />

that it’s just as good as conventional colonoscopy<br />

at detecting precancerous lesions,” says Dr. Yee.<br />

“What’s more, it also reveals previously unsuspected<br />

lesions, tumors, and other problems in nearby<br />

organs such as the liver and kidneys.”<br />

Dr. Yee concedes that since she began working on<br />

virtual colonoscopy over a decade ago, acceptance<br />

<strong>of</strong> the new procedure in the medical community<br />

has not been as swift as she might have liked.<br />

“Nonetheless, thanks in large part to the initial<br />

landmark work that was done here at the San<br />

Francisco VA, virtual colonoscopy has recently been<br />

endorsed by the American Cancer Society in their<br />

cancer screening guidelines,” she notes proudly.<br />

“In fact, in March 2010, President Obama’s colon<br />

cancer screening was performed using virtual<br />

colonoscopy. So we’re definitely moving into a phase<br />

where this technology will be disseminated and<br />

become widely available to millions <strong>of</strong> Americans.”<br />

For Dr. Yee and her VA colleagues in radiology,<br />

imaging goes well beyond thecolon. In 2008, Dr. Yee<br />

presided over the grand opening <strong>of</strong> the 3D Imaging<br />

Laboratory at SFVAMC. “This facility <strong>of</strong>fers our<br />

Veterans cutting-edge, state-<strong>of</strong>-the-art, non-invasive<br />

3D imaging <strong>of</strong> any part <strong>of</strong> the body as a tool in<br />

diagnosis and treatment,” she says. “We can develop<br />

3D models <strong>of</strong> any organ, rotate them in any direction<br />

or orientation, and zoom in and out at will.” Imaging<br />

is not restricted to the major organs: “We see a lot<br />

<strong>of</strong> patients with vascular disease, and we are able<br />

to use 3D images <strong>of</strong> blood vessels to better evaluate<br />

large and small vessel involvement.”<br />

“The 3D lab is also a medical educational tool,” says<br />

Dr. Yee. “Just getting a good image is not enough.<br />

It’s essential to know how to correctly interpret what<br />

you’re seeing. Besides all the UCSF residents who<br />

rotate through here every month, I have medical<br />

students from all over the country who come here<br />

to work with me on 3D imaging research. We have<br />

research fellows, and we train radiologists here<br />

as well. Four times a year, we hold an intensive<br />

interactive workshop on performing and interpreting<br />

virtual colonoscopy. Physicians come from all over<br />

the world to train with us. We have an international<br />

presence.”<br />

NCIRE Report 2008 and 2009 page 9

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