4. Payton, PBD testing for alcohol misuse, 24Apr13

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AST and ALT – The Aminotransferases • useful as markers of hepatic damage from alcohol • much less sensitive than GGT • can be elevated for a wide variety of reasons • do not rise after a single episode • ALT often correlates with GGT • of limited value
MCV • toxic effect on the bone marrow • 35-40% patients • a low sensitivity • other common causes of a high MCV • co-exist in alcohol misuse. • high MCV is 90-95% specific • falls when drinking stops - Slowly
Page 1 and 2: Testing for alcohol misuse at work
Page 4 and 5: Testing for alcohol •Blood •Bre
Page 6 and 7: No excuses • Signed agreement •
Page 8 and 9: GGT Gamma glutamyl transferase •
Page 12 and 13: CDT Carbohydrate deficient transfer
Page 14 and 15: Case 1 Secretary 50 “I drink a bo
Page 16 and 17: 250 229 200 150 100 103 105 alcohol
Page 18 and 19: Case 2 45 year old man in senior po
Page 20 and 21: 900 800 839 700 600 500 400 601 alc
Page 22 and 23: 900 800 839 700 600 500 400 601 alc
Page 24 and 25: 900 800 839 700 600 500 400 601 alc
Page 26 and 27: 39 year old receptionist • Episod
Page 28 and 29: 45 year old college lecturer • Re
Page 30 and 31: Programme results
Page 32 and 33: RTP alcohol use drinking 12 34% tot
Page 34 and 35: Those in work - alcohol use drinkin

4. Payton, PBD testing for alcohol misuse, 24Apr13

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