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device. Concentration of clinical grade SVF cells without the use of a centrifuge would significantly reduce the unit cost and footprint, and ensure gentle cell isolation. Following successful prototype testing, we are currently working towards development of a beta unit that is compliant for testing in the clinic. Such a device is expected to greatly facilitate the penetration of affordable SVF-based therapy in hospitals and clinics in all parts of India and other markets. Acknowledgements: We sincerely thank the following plastic surgeons for their expert opinion and consultancy: Dr. Anantheshwar YN, Dr. Ashok BC, Dr. Prashantha Kesari and Dr. Gunasekar Vuppalapati. Disclosure: This study was completely funded by Stempeutics Research Pvt. Ltd. All authors are employees of Stempeutics Research Pvt. Ltd. and have no other financial affiliations or conflicts of interest related to the subject matter of this presentation topic. 44 IPRAS Journal www.ipras.org Issue 13
Autologous fat grafting (lipofilling) for chronic ulceration on the diabetic foot improves wound healing T. Stasch, J.Hoehne, T.Huynh, R.Baerdemaker, S.Grandel Luisenhospital Aachen, Department of Plastic and Reconstructive Surgery, Aachen, Germany Main author: Dr. Tilman Stasch t.stasch@btinternet.com Purpose: Aim of this case series was to assess the healing progress of chronic, non-healing lower-limb wounds in diabetic patients following peri-lesional autologous fat grafting. Background: Chronic ulceration of the foot is one of the most challenging conditions to treat for plastic surgeons. While autologous fat grafting has been shown to improve the quality and regenerative potential of chronically scarred tissues (1), the effect on wound healing of chronic wounds has only been reported on sporadically. Methods: In this prospective case series, 19 patients with deep, nonhealing chronic foot ulcerations in mostly diabetic patients had previously been unsuccessfully treated at the hospitals foot clinic using traditional methods for a mean of 11 months (range, 2-60). In all patients, peripheral vascular perfusion had been optimized if possible. 2 patients were excluded from the statistical analysis because wound size exceeded the inclusion criteria (wound should be 10 cm 2 can still benefit from lipofilling by allowing formation of granulation tissue which can later be skin grafted. References: 1. Coleman SR, Plast Reconstr Surg. 2006 Sep;118(3 Suppl):108S-120S. Issue 13 www.ipras.org IPRAS Journal 45
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