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FFR-Guided PCI in MVD 137 Patients, Non-Randomized FFR-Guided Angio-Guided Wongpraparut et al. Am J Cardiol 2005;96:877-884. <strong>Stanford</strong>
FFR vs. Angiography for Multivessel Evaluation (F.A.M.E. Study) • Multicenter, international, randomized study including 10 European and 6 U.S. sites. – Co PIs: Nico Pijls (Europe) and Bill Fearon (U.S.) • Compare an angiography-guided strategy to PCI with DES in MVD to an FFR-guided strategy <strong>Stanford</strong>
Page 1 and 2: Coronary Physiology and Imaging Sum
Page 3 and 4: Why do we need physiology? • Limi
Page 5 and 6: Limitations of Angiography: Topol a
Page 7 and 8: Disconnect between Angiography and
Page 9 and 10: Disconnect between Angiography and
Page 11 and 12: Limitations of Noninvasive Imaging:
Page 13 and 14: Nuclear Perfusion Scan Stress Rest
Page 15 and 16: Long Area of Diffuse Disease Stanfo
Page 17 and 18: FFR/CFR/IMR of the RCA CFR IMR FFR
Page 19 and 20: Pullback in Circumflex Most of grad
Page 21 and 22: After “spot-stenting” proximal
Page 23 and 24: FFR after Stenting Pijls et al., Ci
Page 27 and 28: Drug-eluting stents: The “clot”
Page 29: Danger of Deferring PCI if FFR < 0.
Page 35 and 36: Cost Effectiveness of FFR: Clinical
Page 37 and 38: FFR strategy resulted in similar ou

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