Histological Typing of Thyroid Tumours - libdoc.who.int - World ...

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VI Since 1958, WHO has established a number of centres concerned with this subject. The result of this endeavour has been the International Histological Classification of Tirmours, a multivolumed series whose frrst edition was published between 1967 and 1981. The present revised second edition aims to update the classification, reflecting progress in diagnosis and the relevance of tumour types to clinical and epidemiological features.
Preface to Histological Typing of Thyroid Tumours. Second Edition The first edition of Histological Typing of Thyroid Tumoursl was the result of a collaborative effort organized by WHO and carried out by the International Reference,/Collaborating Centre for the Histological Classification of Thyroid Tumours at the Department of Pathology, Faculty of Medicine, University of ZiJ'dch, Switzerland. The Centre was established in 1964 and the classifrcation was published in 7974. In order to keep the classification up to date, a meeting was convened at the Centre in 1986 to discuss proposals for revision (participants listed on pages XI and XII). At this meeting the present classification, definitions and explanatory notes were formulated and recommended for publication. The histological classification of thyroid tumours, which appears on page 3, contains the morphology code numbers of the International Classification of Diseases for Oncology (ICD-O)2 and the Systematized Nomenclature of Medicine (SNOMED).3 It will, of course, be appreciated that the classification reflects the present state of knowledge, and modifications are almost certain to be needed as experience accumulates. Although the present classification has been adopted by the members of the group, it necessarily represents a view from which some pathologists may wish to dissent. 1 Hedinger Chr, Sobin LH (1974) Histological Typing of Thyroid Tumours. Geneva, World Health Organization (International Histological Classification of Tumours, No.11) 2 World Health Organization (1976:) International Classihcation of Diseases for Oncology. Geneva 3 College of American Pathologists (1976) Systematized Nomenclature of Medicine. Chicaso
Page 1 and 2: Histological Typing of Thyroid Tumo
Page 3: General Preface to the Series Among
Page 7 and 8: Table of Contents Introduction Hist
Page 9 and 10: XII Sobin. L.H.. Dn Department of G
Page 11 and 12: aspiration as a pre-operative diagn
Page 13 and 14: Definitions and Explanatory Notes 1
Page 15 and 16: 1.2 Malignant 1.2.1 Follicular Carc
Page 17 and 18: 9 1.2.2 Papillary Carcinoma (Figs.
Page 19 and 20: with metastasis from those that are
Page 21 and 22: 73 pleomorphism than normal C cells
Page 23 and 24: 75 guished from direct extension fr
Page 25 and 26: 77 Exceptionally, teratomas can be
Page 27: Subject Index Page Figures Adenolip
Page 31 and 32: L) G' * ry x340 Fig.6. Follicular a
Page 33 and 34: Fig.9, Atypical adenoma. Considerab
Page 35: )1 "i, tt hig. 13. llralinizing tru
Page 39: 31 x 135 Fig.2l. Follicular carcino
Page 42 and 43: 1A J+ Fig.21. Follicular carcinoma,
Page 44 and 45: x 135 Fig,31. Follicular carcinoma,
Page 46 and 47: Fig.35. Papillary carcinoma. Psammo
Page 49: Fig. 41. Papillary carcinoma, folli
Page 52 and 53: Fig.47. Medullary carcinoma. Same c
Page 54 and 55:
46 x 340 Fig.57. Medullary carcinom
Page 57 and 58:
Fig. 57. Undilferentiated carcinoma
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Fig.67. Undffirentiated carcinoma.
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Fig. 65. Undifferentiated carcinoma
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Fig.1 4, Malignant haemangioendothe
Page 67 and 68:
Fig.78. Intrathyroid paraganglioma.
Page 69:
Fig.87. Metastasis of a renal clear
Page 72 and 73:
X IJ) Fig. 87. Hyperplastic goitre
Page 75 and 76:
W H O I nternational H is tological
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