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Annual Report 2001 - the University of Massachusetts Medical School

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M E S S A G E F R O M T H E P R E S I D E N T<br />

The year <strong>2001</strong> was marked by excitement<br />

and anticipation as we ushered in a new era<br />

<strong>of</strong> biomedical research at <strong>the</strong> <strong>University</strong> <strong>of</strong><br />

<strong>Massachusetts</strong> <strong>Medical</strong> <strong>School</strong>. In just 30 years,<br />

UMMS has risen to achieve national prominence with our<br />

ambitious research enterprise; funding is projected to reach<br />

$123 million this year. Ranked second out <strong>of</strong> 10 Nor<strong>the</strong>ast<br />

public medical schools in funding from <strong>the</strong> National Institutes<br />

<strong>of</strong> Health—265 individual awards with 14 program, project<br />

and center grants—and an impressive fourth among 30 medical<br />

schools founded since 1965, UMMS is on <strong>the</strong> rise, providing<br />

<strong>the</strong> momentum for <strong>the</strong> institution to become one <strong>of</strong> <strong>the</strong><br />

outstanding research medical schools in <strong>the</strong> country.<br />

In October, a dream was realized on campus with <strong>the</strong> dedication<br />

and opening <strong>of</strong> <strong>the</strong> new research laboratory building.<br />

In just over two years, <strong>the</strong> structure was designed and constructed<br />

to facilitate <strong>the</strong> latest in cutting-edge biomedical<br />

research. Made possible by <strong>the</strong> unwavering support <strong>of</strong> <strong>the</strong><br />

Worcester Foundation and <strong>the</strong> UMMS community, <strong>the</strong><br />

building stands as a symbol <strong>of</strong> <strong>the</strong> successful collaboration that<br />

has defined <strong>the</strong> relationship <strong>of</strong> <strong>the</strong> two since <strong>the</strong>ir merger in 1997.<br />

Recognizing that <strong>the</strong> key to fur<strong>the</strong>ring growth is in <strong>the</strong><br />

recruitment <strong>of</strong> outstanding scientists, <strong>the</strong> 360,000-squarefoot<br />

facility will house 100 new investigators, <strong>of</strong> which 30<br />

have already been recruited from some <strong>of</strong> <strong>the</strong> most prestigious<br />

universities and institutes in <strong>the</strong> country. These scientists,<br />

along with our current accomplished faculty, will undertake<br />

research to discover <strong>the</strong> causes <strong>of</strong> and cures for <strong>the</strong> most<br />

devastating diseases <strong>of</strong> our time. They will explore <strong>the</strong><br />

genetic basis <strong>of</strong> disease, leading to fur<strong>the</strong>r understanding <strong>of</strong><br />

how genes work, and develop gene <strong>the</strong>rapy techniques for<br />

<strong>the</strong> insertion <strong>of</strong> new genes into cells. They will tackle diabetes<br />

and o<strong>the</strong>r autoimmune diseases, and embark on new frontiers<br />

in immunology. Research programs in neuroscience will be<br />

launched, with implications for disorders ranging from<br />

Sudden Infant Death Syndrome to Alzheimer’s disease and<br />

<strong>the</strong> understanding <strong>of</strong> <strong>the</strong> genetics <strong>of</strong> mental illness.<br />

Program in Chemical Biology and appointed Tariq Rana,<br />

PhD, as its first director, who will guide <strong>the</strong> program in<br />

applying <strong>the</strong> power <strong>of</strong> chemistry to <strong>the</strong> molecular basis <strong>of</strong><br />

disease.We welcomed nationally recognized dermatologist<br />

and virologist Elliot Androphy, MD, to <strong>the</strong> Department <strong>of</strong><br />

Medicine as <strong>the</strong> Barbara and Nathan Greenberg Chair in<br />

Biomedical Research and <strong>the</strong> Department <strong>of</strong> Medicine’s vice<br />

chair for research.<br />

Among our ranks, we count two<br />

<strong>of</strong> <strong>the</strong> most highly cited scientists<br />

in <strong>the</strong> world and three Howard<br />

Hughes <strong>Medical</strong> Institute Investigators.<br />

Our scientists are publishing<br />

in <strong>the</strong> most prestigious journals,<br />

including Cell, New England Journal<br />

<strong>of</strong> Medicine, Science and Nature and<br />

presenting <strong>the</strong>ir research at distinguished<br />

conferences around <strong>the</strong><br />

world. And to bring <strong>2001</strong> to a<br />

close, we welcomed four <strong>of</strong> <strong>the</strong><br />

country’s pre-eminent researchers<br />

to this fall’s Scientific Symposium,<br />

reflecting our highest aspirations<br />

for scientific achievement.<br />

In <strong>the</strong> coming year, our priority will be <strong>the</strong> recruitment <strong>of</strong><br />

a director for our Cancer Center. I am looking forward to<br />

an incredible 2002 for <strong>the</strong> UMMS research enterprise.<br />

John L. Sullivan, MD<br />

Director, Office <strong>of</strong> Research<br />

UMMS Pr<strong>of</strong>essor <strong>of</strong> Pediatrics and Molecular Medicine<br />

This exciting year also encompassed a series <strong>of</strong> events and<br />

accomplishments celebrating superior science.With <strong>the</strong><br />

support <strong>of</strong> a four-year, multi-million dollar grant from <strong>the</strong><br />

Howard Hughes <strong>Medical</strong> Institute, we implemented <strong>the</strong><br />

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