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COVER STORY<br />

and package handling, stability and reagent<br />

management, and other R&D applications.”<br />

Such features are offered as part of<br />

a single IT platform that can be configured<br />

to afford flexibility at individual laboratories<br />

but also promote standard practices at<br />

global research organizations.<br />

THE COMPANY’S most recent LIMS adaptation<br />

is software for accessing, reporting,<br />

and analyzing disparate data. For this,<br />

Labvantage has formed a partnership with<br />

InforSense, a supplier of data integration<br />

and predictive analysis software. Under the<br />

agreement, Labvantage will market Infor-<br />

Sense’s software along with its Sapphire<br />

LIMS.<br />

Simon Beaulah, senior marketing manager<br />

for InforSense, sees advantages to both<br />

laboratory managers and bench scientists in<br />

combining LIMS and data analysis software.<br />

“We provide visualization tools through the<br />

Web,” he says. “You can think of it as scientific<br />

business intelligence. It is a matter of<br />

getting the right data to the scientist so that<br />

the scientist can make the right decision.”<br />

Translational research is a major impetus for<br />

adding an analysis dimension to standard<br />

benchtop computing, according to Beaulah.<br />

James DeGreef, vice president of market<br />

strategy with LIMS provider GenoLogics,<br />

says his firm is working on integrating its<br />

LIMS with InforSense software. “LIMS and<br />

analytics working together is a trend now,”<br />

DeGreef says. “It’s a natural fit.” Researchers<br />

are interested in integrating these functions<br />

to advance proteomics and genomics<br />

research, which are key practices among<br />

GenoLogics’ target customers.<br />

Like Labvantage, GenoLogics adds features<br />

to its LIMS software on a regular basis.<br />

But partnership with other software suppliers<br />

has long been a route to linking with<br />

completely different kinds of software and<br />

automation. “A lot of our work is done with<br />

instrumentation providers,” DeGreef says,<br />

citing a partnership with Illumina, a gene sequencing<br />

and genotyping systems supplier.<br />

According to DeGreef, the LIMS market<br />

is trending away from generic software<br />

to products targeted at specific areas of<br />

research. GenoLogics, which has always<br />

targeted the life sciences, offers a basic<br />

system called Omix, as well as a specialized<br />

product for genomics called Geneus and<br />

one for proteomics called Proteus.<br />

Given the need for software customization<br />

and the availability of Web-based tools<br />

to connect software, Biomatrica, a LIMS<br />

supplier launched five years ago, sells its<br />

software as a series of modular applications.<br />

“We are seeing a trend away from big, monolithic<br />

LIMS systems that try to capture all the<br />

data at one time,” Brian Baumann, director<br />

of software products, says. Although largescale<br />

systems might work well in biobanking<br />

applications, Baumann says, drug and biotech<br />

research can be handled more efficiently<br />

by linking modular software components<br />

at the bench to a central database.<br />

Baumann adds that new product development<br />

at Biomatrica also focuses on<br />

ease of use—developing software that can<br />

be maintained by the researcher. “In a lot<br />

of big pharma and<br />

biotechnology companies,<br />

IT departments<br />

don’t support scientific<br />

software,” he<br />

says. “They deal more<br />

with IT infrastructure.<br />

LIMS needs to<br />

be made more intuitive<br />

to the user.” And<br />

LIMS must be easily<br />

integrated with other<br />

laboratory software<br />

and automation, extending<br />

the modular<br />

approach into a multivendor<br />

IT landscape.<br />

Some software<br />

developers have<br />

launched new products<br />

operating at the<br />

middle level of the lab<br />

IT pyramid that are<br />

specifically designed<br />

to link research software<br />

and databases.<br />

BioFortis, for example,<br />

has introduced<br />

software called Lab-<br />

Matrix that vets data<br />

collected by LIMS at<br />

the laboratory level<br />

and routes it where it is needed.<br />

SNAPSHOT<br />

Laboratory<br />

information<br />

management<br />

systems are<br />

taking on the<br />

reams of data<br />

produced by life<br />

sciences research<br />

automation.<br />

“LIMS are involved in gene expression,<br />

imaging, and converting information into<br />

numbers, but not every number needs to be<br />

carried up the pyramid,” Jian Wang, chief<br />

WWW.CEN-ONLINE.ORG 16 NOVEMBER 24, 2008

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