Harmonic Regression in the Biological Setting

06.11.2014 • Views

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Harmonic Regression in the Biological Setting

Harmonic Regression in the Biological Setting

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Diurnal Rhythm of Systolic BP <strong>in</strong> 6 Individual Subjects

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Distribution of Peak Times Hour Systolic BP N % 0-4 2 5 4-8 2 5 8-12 12 29% 12-16 8 20% 16-20 13 32% 20-24 4 10% 41

Diurnal Rhythm of Systolic BP <strong>in</strong> 6 Individual Subjects

Page 1 and 2: Harmonic Regression in the Biologic
Page 3 and 4: Two Harmonic Model R it = M i + A 1
Page 5: Diurnal Rhythm of Mean Systolic BP
Page 9 and 10: Mean of individual subject amplitud
Page 11: Treatment Effect over 24 Hours •
Page 17 and 18: Example: 3-hour Moving Average X t
Page 22: Change from baseline in UUI Rate by