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Sutter Institute for Medical Research 2008 Annual Report

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“There are a lot of unknowns in<br />

pediatric neurology and a great<br />

deal that can be learned by turning<br />

clinical observations into research<br />

studies that prove or disprove those<br />

observations. When I started seeing<br />

children with Down’s syndrome<br />

exhibiting signs of autism, I<br />

wondered if epileptic episodes might<br />

be occurring in these children.<br />

Working with SIMR allowed me to<br />

pursue that idea and verify that there<br />

may indeed be a connection. In fact,<br />

the opportunity to do research is one<br />

of the things that drew me to <strong>Sutter</strong>.<br />

There is a large patient population<br />

and ample support from SIMR to<br />

initiate, conduct and complete a<br />

research project.”<br />

Michael Chez, M.D.<br />

<strong>Medical</strong> Director, Pediatric Neurology<br />

Symposium Highlights<br />

One of the lesser-known opportunities SIMR<br />

provides is the chance <strong>for</strong> investigators to pursue<br />

research interests that lie outside clinical trials.<br />

Since 1989, dozens of physicians and other <strong>Sutter</strong><br />

practitioners have initiated research projects. In most<br />

instances, these researchers apply <strong>for</strong> and receive a<br />

grant funded by donations and other philanthropic<br />

gifts made by <strong>Sutter</strong> <strong>Medical</strong> Center Foundation.<br />

Over the years, many SIMR researchers have received<br />

national and international recognition <strong>for</strong> their work.<br />

In October <strong>2008</strong>, we gathered a few together <strong>for</strong> a<br />

local symposium presented to <strong>Sutter</strong> colleagues and<br />

members of the Greater Sacramento community. <strong>Research</strong><br />

scientist Carol Parise and SIMR staff members<br />

Bobbie Benabides, Dorothy Wullenwaber, Tammy<br />

Donnel, and Marilyn Dela Cruz, organized the symposium.<br />

Presentations were made by six researchers<br />

who recently completed studies with SIMR support:<br />

Nate Hitzeman, M.D.<br />

Affect of Personalized <strong>Annual</strong> Health Reminder Cards<br />

(PAHRC) on Completion of Age-Appropriate Health<br />

Maintenance Projective Objective<br />

A study to determine if personalized reminders of<br />

health maintenance items sent to patients on their<br />

birthdays would improve their completion of patient<br />

specific health maintenance requirements within six<br />

months. Results showed no increase from this lowcost<br />

intervention.<br />

Vincent Caggiano, M.D.<br />

Age, Race/Ethnicity, and Breast Cancer Subtypes in<br />

Cali<strong>for</strong>nia<br />

A series of studies conducted by analyzing 6,370<br />

records within the Cali<strong>for</strong>nia Cancer Registry<br />

database showing an invasive breast cancer<br />

subtype featuring negative receptors <strong>for</strong> estrogen,<br />

progesterone and human epidermal growth factor<br />

receptor 2 (triple negative). The widely published<br />

and presented studies conclusively showed that<br />

the subtype is more prevalent and deadly in<br />

young African American and Hispanic women, a<br />

finding that can help doctors look <strong>for</strong> and treat this<br />

challenging subtype.

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