Chronic Coronary Artery Disease Management - Dr Cutlip.pdf
Chronic Coronary Artery Disease Management - Dr Cutlip.pdf
Chronic Coronary Artery Disease Management - Dr Cutlip.pdf
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Role of Intensive Therapy<br />
What is the BP target?<br />
ADVANCE (N= 11,140, Type 2 DM at high CV risk)<br />
P=0.04<br />
• Fixed dose perindopril +<br />
indapamide versus placebo<br />
Mean FU = 4.3 years<br />
P=0.02<br />
P=0.03<br />
• Other agents including ACE-I<br />
(45% in placebo group) continued<br />
• Rx not guided by BP goal, but<br />
lower in intense group (134.5/74<br />
vs 140/76, p
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