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Guidelines for the Diagnosis and Management of Asthma

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Managing <strong>Asthma</strong> Long Term<br />

GOAL OF THERAPY: CONTROL OF ASTHMA<br />

Reduce Impairment<br />

■<br />

■<br />

■<br />

■<br />

■<br />

Prevent chronic <strong>and</strong> troublesome symptoms (e.g., coughing or breathlessness in <strong>the</strong> daytime, in <strong>the</strong> night, or after exertion).<br />

Require infrequent use (≤2 days a week) <strong>of</strong> inhaled SABA <strong>for</strong> quick relief <strong>of</strong> symptoms (not including prevention <strong>of</strong><br />

exercise-induced bronchospasm [EIB]).<br />

Maintain (near) normal pulmonary function.<br />

Maintain normal activity levels (including exercise <strong>and</strong> o<strong>the</strong>r physical activity <strong>and</strong> attendance at school or work).<br />

Meet patients’ <strong>and</strong> families’ expectations <strong>of</strong> <strong>and</strong> satisfaction with asthma care.<br />

Reduce Risk<br />

■<br />

■<br />

■<br />

Prevent recurrent exacerbations <strong>of</strong> asthma <strong>and</strong> minimize <strong>the</strong> need <strong>for</strong> ED visits or hospitalizations.<br />

Prevent loss <strong>of</strong> lung function; <strong>for</strong> children, prevent reduced lung growth.<br />

Provide optimal pharmaco<strong>the</strong>rapy with minimal or no adverse effects <strong>of</strong> <strong>the</strong>rapy.<br />

Achieving <strong>and</strong> maintaining asthma control requires<br />

four components <strong>of</strong> care: assessment <strong>and</strong> monitoring,<br />

education <strong>for</strong> a partnership in care, control <strong>of</strong> environmental<br />

factors <strong>and</strong> comorbid conditions that<br />

affect asthma, <strong>and</strong> medications. A stepwise approach<br />

to asthma management incorporates <strong>the</strong>se four<br />

components, emphasizing that pharmacologic<br />

<strong>the</strong>rapy is initiated based on asthma severity <strong>and</strong><br />

adjusted (stepped up or down) based on <strong>the</strong> level <strong>of</strong><br />

asthma control. Special considerations <strong>of</strong> <strong>the</strong>rapeutic<br />

options within <strong>the</strong> stepwise approach may be<br />

necessary <strong>for</strong> situations such as exercise-induced<br />

bronchospasm (EIB), surgery, <strong>and</strong> pregnancy.<br />

Four Components <strong>of</strong> <strong>Asthma</strong> Care<br />

Component 1: Assessing <strong>and</strong> Monitoring <strong>Asthma</strong><br />

Severity <strong>and</strong> <strong>Asthma</strong> Control<br />

The functions <strong>of</strong> assessment <strong>and</strong> monitoring are<br />

closely linked to <strong>the</strong> concepts <strong>of</strong> severity, control, <strong>and</strong><br />

responsiveness to treatment:<br />

■ Severity: <strong>the</strong> intrinsic intensity <strong>of</strong> <strong>the</strong> disease<br />

process. Severity is most easily <strong>and</strong> directly measured<br />

in a patient who is not receiving long-term control<br />

<strong>the</strong>rapy. Severity can also be measured, once<br />

asthma control is achieved, by <strong>the</strong> step <strong>of</strong> care<br />

(i.e., <strong>the</strong> amount <strong>of</strong> medication) required to<br />

maintain control.<br />

■ Control: <strong>the</strong> degree to which <strong>the</strong> manifestations <strong>of</strong><br />

asthma are minimized by <strong>the</strong>rapeutic intervention<br />

<strong>and</strong> <strong>the</strong> goals <strong>of</strong> <strong>the</strong>rapy are met.<br />

■ Responsiveness: <strong>the</strong> ease with which asthma<br />

control is achieved by <strong>the</strong>rapy.<br />

<strong>Asthma</strong> severity <strong>and</strong> asthma control include <strong>the</strong><br />

domains <strong>of</strong> current impairment <strong>and</strong> future risk.<br />

■ Impairment: frequency <strong>and</strong> intensity <strong>of</strong> symptoms<br />

<strong>and</strong> functional limitations <strong>the</strong> patient is currently<br />

experiencing or has recently experienced.<br />

Managing <strong>Asthma</strong> Long Term<br />

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