Helicobacter pylori.pdf - Academic lab pages - School of Biosciences
Helicobacter pylori.pdf - Academic lab pages - School of Biosciences
Helicobacter pylori.pdf - Academic lab pages - School of Biosciences
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Eppinger et al (2006)<br />
Humans have been colonised by H.<strong>pylori</strong> for at least 60,000 years<br />
Evolutionary scientists have used H.<strong>pylori</strong> to track out <strong>of</strong> Africa<br />
migration<br />
Neighbour-joining trees show that there is less diversity in European<br />
strains than African strains.<br />
The African strain is more closely related to the big-cat strain<br />
H.acinonychis Sheeba than the European strain is ... Did big cats<br />
catch H.<strong>pylori</strong> from eating humans???<br />
Atherton and Blaser (2009)<br />
Since the out <strong>of</strong> Africa migration, it has been a part <strong>of</strong> the natural<br />
micr<strong>of</strong>lora <strong>of</strong> humans<br />
Modifies the host immune system long term and affects acid<br />
homeostastis<br />
Now, H.<strong>pylori</strong> is decreasing in prevalence due to improved living<br />
conditions<br />
Other diseases have emerged instead: gastroesophageal reflux<br />
disease, obesity, type 2 diabetes, allergies<br />
Is this disappearance and emergence linked?
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