Ultrasound Imaging in Multifetal Pregnancies: Its
Ultrasound Imaging in Multifetal Pregnancies: Its
Ultrasound Imaging in Multifetal Pregnancies: Its
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Tw<strong>in</strong> Anemia-Polycythemia Sequence<br />
(TAPS)<br />
• Larger <strong>in</strong>tertw<strong>in</strong> hemoglob<strong>in</strong> difference w/o signs of<br />
TOPS<br />
• Intertw<strong>in</strong> blood transfusion w/o hormonal<br />
imbalance<br />
• Post laser: ex-recipient anemic w/ ex-donor<br />
polycythemic ~ 77%<br />
• Spontaneous reported as early as 16 weeks<br />
Study N Post-laser<br />
Robyr, 2006 101 13%<br />
Habli, 2009 152 2%<br />
Slagehekke,2010 276 8%<br />
Spontaneous*<br />
Lewi et al, 2009 202 5%<br />
Lopriore, 2010 113 5%<br />
Slagehekke F et al Fetal Diagn Therapy 2010
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