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T-Mobile’s dynamic management team has imported to the U.S. market (apparently from<br />

Softbank in Japan). Without a combination, Sprint and T-Mobile are expected to play out<br />

the sell-side narrative, ceding share while becoming increasingly ripe targets for the<br />

massive financial firepower of AT&T and Verizon. While the environment for legitimate<br />

business combinations faces potentially unfriendly regulatory dynamics, the combination<br />

of Sprint and T-Mobile creates the only real counterbalance to a decade-long market and<br />

profit share grab by the industry’s two largest players.<br />

Equity Position: Intrexon Corporation (“Intrexon”)<br />

We initially invested in Intrexon in 2011 in a private round and have continued to<br />

accumulate shares since its IPO in August <strong>2013</strong>. We believe that Intrexon is an innovation<br />

leader in synthetic biology with a unique value proposition and proven leadership team.<br />

Most attractive to us is Intrexon’s potential to transform multiple industries, including the<br />

health, food, and energy markets.<br />

Synthetic biology is an emerging discipline that applies engineering design principles to<br />

biologic systems. Broadly speaking, synthetic biology is about the design, modification, and<br />

regulation of gene programs to produce a desired outcome, such as the production of a<br />

novel antibody from a cell culture, the optimization of a specific gene trait in crops, or the<br />

amplification of wild type natural gas metabolism into an industrially feasible process.<br />

Over the past 15 years, Intrexon has developed deep expertise in synthetic biology as well<br />

as the adjacent fields of process optimization and data analysis to create a unique<br />

technology platform that enables the iterative, directed improvement of experimental<br />

design.<br />

To leverage its technology with collaborators, Intrexon has developed a unique business<br />

model that centers on Exclusive Channel Collaborations (ECCs) with partners. In exchange<br />

for providing access to their technology, Intrexon receives cost reimbursement (thus<br />

mitigating the need to raise additional external funds) and significant downstream<br />

economics. Because Intrexon’s technology is scalable, its capacity to sign ECCs across<br />

multiple industries is limited only by the ambition of its partners. Indeed, to date, Intrexon<br />

has already signed over 15 ECCs including, notably, with Johnson & Johnson. Over the<br />

course of 2014 and beyond, we anticipate that Intrexon will sign multiple ECCs, creating a<br />

broad pipeline of projects and diversifying away from specific product risk.<br />

Intrexon is led by Chairman and CEO Randal J. Kirk, one of the most successful healthcare<br />

leaders of all time. Kirk founded and led New River Pharmaceuticals until its acquisition by<br />

Shire, and led Clinical Data through the successful development and approval of the antidepressant<br />

Viibryd before selling the company to Forest. While his track record of value<br />

creation speaks for itself, we especially like that Kirk has personally invested significantly<br />

10

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