Third-Point-Q4-2013-Investor-Letter-TPOI
Third-Point-Q4-2013-Investor-Letter-TPOI
Third-Point-Q4-2013-Investor-Letter-TPOI
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T-Mobile’s dynamic management team has imported to the U.S. market (apparently from<br />
Softbank in Japan). Without a combination, Sprint and T-Mobile are expected to play out<br />
the sell-side narrative, ceding share while becoming increasingly ripe targets for the<br />
massive financial firepower of AT&T and Verizon. While the environment for legitimate<br />
business combinations faces potentially unfriendly regulatory dynamics, the combination<br />
of Sprint and T-Mobile creates the only real counterbalance to a decade-long market and<br />
profit share grab by the industry’s two largest players.<br />
Equity Position: Intrexon Corporation (“Intrexon”)<br />
We initially invested in Intrexon in 2011 in a private round and have continued to<br />
accumulate shares since its IPO in August <strong>2013</strong>. We believe that Intrexon is an innovation<br />
leader in synthetic biology with a unique value proposition and proven leadership team.<br />
Most attractive to us is Intrexon’s potential to transform multiple industries, including the<br />
health, food, and energy markets.<br />
Synthetic biology is an emerging discipline that applies engineering design principles to<br />
biologic systems. Broadly speaking, synthetic biology is about the design, modification, and<br />
regulation of gene programs to produce a desired outcome, such as the production of a<br />
novel antibody from a cell culture, the optimization of a specific gene trait in crops, or the<br />
amplification of wild type natural gas metabolism into an industrially feasible process.<br />
Over the past 15 years, Intrexon has developed deep expertise in synthetic biology as well<br />
as the adjacent fields of process optimization and data analysis to create a unique<br />
technology platform that enables the iterative, directed improvement of experimental<br />
design.<br />
To leverage its technology with collaborators, Intrexon has developed a unique business<br />
model that centers on Exclusive Channel Collaborations (ECCs) with partners. In exchange<br />
for providing access to their technology, Intrexon receives cost reimbursement (thus<br />
mitigating the need to raise additional external funds) and significant downstream<br />
economics. Because Intrexon’s technology is scalable, its capacity to sign ECCs across<br />
multiple industries is limited only by the ambition of its partners. Indeed, to date, Intrexon<br />
has already signed over 15 ECCs including, notably, with Johnson & Johnson. Over the<br />
course of 2014 and beyond, we anticipate that Intrexon will sign multiple ECCs, creating a<br />
broad pipeline of projects and diversifying away from specific product risk.<br />
Intrexon is led by Chairman and CEO Randal J. Kirk, one of the most successful healthcare<br />
leaders of all time. Kirk founded and led New River Pharmaceuticals until its acquisition by<br />
Shire, and led Clinical Data through the successful development and approval of the antidepressant<br />
Viibryd before selling the company to Forest. While his track record of value<br />
creation speaks for itself, we especially like that Kirk has personally invested significantly<br />
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