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2010 MSARF Symposium Participants - Foundation for Anesthesia ...

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overall mortality reduction was found compared to standard of care. The current study evaluates standard of care fluids<br />

versus Hextend plus standard of care <strong>for</strong> the resuscitation of trauma patients requiring immediate operative intervention<br />

within 4 hours of arrival. Patients were further divided into groups based on the mechanism of injury (penetrating or<br />

blunt), and data <strong>for</strong> the first 24 hours was collected. Outcomes were determined using hemodynamic, laboratory, and<br />

fluid data. Statistical analysis showed no significant demographic differences between the standard of care fluid and the<br />

Hextend group. Patients receiving Hextend therapy were in worse condition than the standard of care group on arrival to<br />

the hospital, with a higher initial heart rate, and lower baseline hematocrit. Despite this, the Hextend group required less<br />

fluids and blood products within the first 24 hours, with a greater urine output. This data supports the use of Hextend by<br />

the military <strong>for</strong> both blunt and penetrating trauma, but to better understand the efficacy, a randomized clinical trial is<br />

necessary.<br />

Student Name: Maleeha Mohiuddin<br />

Host Department: Northwestern University's Feinberg School of Medicine<br />

Primary Mentor Name: Paloma Toledo, MD, MPH<br />

Additional Mentors: Cynthia Wong, MD<br />

Title of Research Project: Racial/Ethnic Differences in Health Literacy and Use of Labor Neuraxial Analgesia<br />

Background: Neuraxial analgesia is the most effective method of relieving labor pain; however, a racial/ ethnic disparity<br />

exists in labor neuraxial analgesia use. We hypothesized that patients with low health literacy would be less likely to<br />

utilize neuraxial analgesia than patients with high health literacy.<br />

Methods: A survey was developed and tested <strong>for</strong> content validity. In-person interviews were conducted upon admission to<br />

the Labor and Delivery Unit, prior to a pre-anesthetic consultation. Data collected included demographic data, analgesic<br />

plans, source used <strong>for</strong> labor analgesia in<strong>for</strong>mation, knowledge of neuraxial analgesia, and health literacy (s-TOFLA). Data<br />

were analyzed using ?2 statistic. P

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