Michael Pinsky RV function under pressure

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RV Adapts to Increased Pressure Loads in Response to Increased Wall Stress • Hypertrophy is initially heterogeneous – Outflow track hypertrophies first because it contracts last and thus sees the highest wall stress during systole •RV remodeling occurs with pulmonary hypertension before Pra
Modeling RV Wall Strain during Pulmonary Hypertension 1. Tension in one principal curvature T = ⎛ P ⎞ ⎛ ⎜ ab ⎝ 2 ⎟ a 1+ b2 ⎠ a + ⎞ ⎜ b2 ⎟ ⎝ 2 c 2 ⎠ 2A 2. Applied lidto each T ab ,TT ac ,TT ba ,TT bc ,TT ca ,TT cb direction a, b and c 3. Average Orthogonal ⎛ T ab + T ac ⎞ T a = ⎜ ⎟ ⎡ ⎛ T Tension ⎝ 2 ⎠ a ⎞ ⎜ ⎟ x 2 ⎝ a ⎠ a + ⎛ T ⎞ b ⎜ ⎟ y 2 ⎛ ⎢ ⎜ ⎣ 2 ⎝ b ⎠ ⎝ T 4. Average Tension avg = x 2 tA + y 2 + z2 at Any Point a 4 b 4 c 4 5. Product of Principal ( T gv ) 2 = T ab T ac + T T 2 ba bc + T T 2 ca cb Tensions a b c ( ) x 2 6. Maximal Tension at a Point T max = T avg + ( T ac ) 2 − T gv 7. Maximal Stress ( ) y 2 ( ) z2 b + T ⎞ c 2 c ⎠ c 2 ⎟ z2 c 2 ( ) 2 σ max = T max max h Regen. Ann Biomed Eng 24:400-17, 1996 ⎤ ⎥ ⎦
Page 1 and 2: Right Ventricular Function Under Pr
Page 3 and 4: ECG-Gated Gated Multislice Computed
Page 5 and 6: RV Systolic Function and Aortic Pre
Page 7 and 8: RV Systolic Function and Aortic Pre
Page 9 and 10: Effects of Pulmonary Hypertension o
Page 11 and 12: On the Nature of LV Contraction Seq
Page 13 and 14: Bi-Ventricular End-Systolic Pressur
Page 15 and 16: Left Ventricular Function (generate
Page 17 and 18: Right Ventricular Ejection Although
Page 19 and 20: Effect of isolated LV contraction o
Page 21 and 22: Partial lA Aortic Occlusion Left ve
Page 23 and 24: Ventricular Interdependence • Tra
Page 25 and 26: Effect of Partial Pulmonary Artery
Page 27 and 28: Right Ventricular Afterload Questio
Page 29 and 30: Mild RV Loading Decreases RV Wall S
Page 31 and 32: Computed Tomography of RV Normal RV
Page 33: RVOT ES Wall Stress vs. Wall Thickn
Page 37 and 38: Modeling RV Wall Strain during Pulm
Page 39 and 40: RV Adaptation to Pressure 4CH Longi
Page 41 and 42: Severe PAH with Decompensated RV 4C
Page 43 and 44: Clinical i l Implications • Right

Michael Pinsky RV function under pressure

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