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B OOKSHELF G ARY V ANDER A RK, M D<br />

A Tale <strong>of</strong> Neurosurgery’s Founder<br />

A Compelling Cushing Inspired a Specialty<br />

Harvey Cushing:<br />

A Life in Surgery,<br />

by Michael Bliss,<br />

2005, Oxford<br />

University Press,<br />

591 pp., $40<br />

($26.40 for AANS<br />

members).<br />

Canadian historian Michael Bliss,<br />

MD, author <strong>of</strong> William Osler: A Life<br />

in Medicine, has written a new book<br />

about neurosurgery’s founder, Harvey<br />

Cushing. It is a book that everyone<br />

should read.<br />

Bliss based this book on a host <strong>of</strong> Cushing<br />

family papers unavailable to earlier<br />

biographers. As a result, this is a less constrained<br />

and more personal biography.<br />

Cushing still comes through as a daring<br />

innovator and icon, but he is also revealed<br />

as a real person with many foibles.<br />

Born in Cleveland in 1869, Cushing<br />

graduated from Yale in 1891 and Harvard<br />

Medical School in 1895, staying in Boston<br />

for an internship at Massachusetts General<br />

Hospital. Then Baltimore beckoned with<br />

its new, graciously endowed Johns Hopkins<br />

Hospital and Medical School. Halsted,<br />

Welch, Kelly and Osler all influenced Cushing,<br />

although during his training Cushing<br />

had limited contact with Halsted, but it was<br />

Osler who quickly became a surrogate<br />

father figure for the young surgical pioneer.<br />

A most significant part <strong>of</strong> Cushing’s<br />

development then followed in his “Wanderjahr”<br />

<strong>of</strong> 1900–01, when he visited Europe.<br />

There, Cushing was shocked by the lack <strong>of</strong><br />

surgical asepsis, concern for the feelings <strong>of</strong><br />

the patients and consistency <strong>of</strong> surgical<br />

techniques. He also did the research that led<br />

to elucidation <strong>of</strong> the “Cushing reflex.”<br />

The next year, Cushing married Kate<br />

Crowell and they moved into the house next to<br />

the Oslers in Baltimore. Cushing was declared<br />

the neurosurgical specialist among the Hopkins<br />

surgeons. His interest in brain surgery<br />

resulted from his ability to successfully treat<br />

trigeminal neuralgia by gasserian ganglionectomy.<br />

As a result, he began to do brain tumor<br />

operations, and in 1902 performed a successful<br />

nerve anastamosis.<br />

Before 1900 more than 500 general surgeons<br />

in the United States had done operations<br />

on the brain. Cushing, however,<br />

brought to the then-dismal field a highly<br />

developed set <strong>of</strong> techniques to control<br />

bleeding, crucial knowledge <strong>of</strong> and sensitivity<br />

to the problem <strong>of</strong> intracranial pressure,<br />

an awesome dexterity, and an equally<br />

He was the kind <strong>of</strong> man<br />

you would work with,<br />

admire and respect, but<br />

not one you would like.<br />

awesome combination <strong>of</strong> enthusiasm and<br />

determination to succeed.<br />

During the first decade <strong>of</strong> the 20th century,<br />

Cushing established neurosurgery as a<br />

specialty. He developed subtemporal decompression<br />

as his basic intracranial operation. It<br />

was his all-purpose response to any cerebral<br />

symptomology. Halsted is said to have commented<br />

during these years that he didn’t<br />

know whether to refer to “poor Cushing’s<br />

patients or Cushing’s poor patients.”<br />

But he also increasingly dedicated himself<br />

to the pituitary toward the end <strong>of</strong> that<br />

decade. By 1912 he had data on 48 patients<br />

and wrote The Pituitary Body and Its Disorders.<br />

It was not until many years later that he<br />

described the syndrome <strong>of</strong> hypersecretion<br />

due to a basophilic adenoma that came to be<br />

known as Cushing’s syndrome.<br />

Cushing is not presented in this book as the<br />

well-rounded person we would like our residents<br />

to become. He was not a good husband;<br />

he was an absentee father, and in the operating<br />

room he could be peevish and mean. One<br />

Hopkins resident said, “He was the kind <strong>of</strong><br />

man you would work with, admire and<br />

respect, but not one you would like.”<br />

World War I, in which Cushing served<br />

two tours <strong>of</strong> duty, definitely took its toll.<br />

While in France he probably had the dreadful<br />

influenza and then post-flu Guillain-<br />

Barre syndrome. This, combined with<br />

Berger’s disease made worse by his smoking,<br />

resulted in significant pain and lower extremity<br />

disability. He also learned something<br />

from the war, however—how to operate<br />

more rapidly. By the time the war ended, he<br />

was able to do eight major cases in a day.<br />

I particularly enjoyed the portions <strong>of</strong><br />

this book that deal with the relationship<br />

between Cushing and Osler. The book’s<br />

most moving scene is the death <strong>of</strong> Osler’s<br />

son, Revere, on the operating table in Flanders.<br />

William Osler himself died in December<br />

1919, and within a few months his<br />

widow asked Cushing to write his biography.<br />

Cushing responded by doubling his<br />

workload to write more than a million<br />

words about his mentor. The final work was<br />

edited down to the two-volume The Life <strong>of</strong><br />

Sir William Osler, published in 1925. One<br />

year later Cushing was awarded the Pulitzer<br />

Prize in biography for this work.<br />

Bliss refers to Cushing as “the Babe Ruth<br />

<strong>of</strong> his game.” Interestingly, his subject<br />

enjoyed the athletic analogy, too. Cushing<br />

wrote to his oldest son, who was struggling<br />

with his studies, “Life all round is a kind <strong>of</strong><br />

sporting event and the best any <strong>of</strong> us can do<br />

is to try continually to improve our game.”<br />

Reading this book will help you improve<br />

your own game. 3<br />

Gary Vander Ark, MD, is director <strong>of</strong> the Neurosurgery<br />

Residency Program at the University <strong>of</strong> Colorado. He is<br />

the 2001 recipient <strong>of</strong> the AANS Humanitarian Award.<br />

Volume 14, Number 4 • AANS Bulletin 41

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