Cardiopulmonary Bypass in infants and children - Sha-conferences ...
Cardiopulmonary Bypass in infants and children - Sha-conferences ...
Cardiopulmonary Bypass in infants and children - Sha-conferences ...
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Hematocrit<br />
• Newburger JW, et al. R<strong>and</strong>omized trial of hematocrit 25%<br />
versus 35% dur<strong>in</strong>g hypothermic cardiopulmonary bypass <strong>in</strong><br />
<strong>in</strong>fant heart surgery. J Thorac Cardiovasc Surg. 2008<br />
Feb;135(2):347-54, 354.e1-4.<br />
No difference between Hct 25% <strong>and</strong> 35%<br />
• Wypij D, et al.J Thorac Cardiovasc Surg. 2008 Feb;135(2):347-<br />
54, 354.e1-4. A hematocrit level at the onset of low-flow<br />
cardiopulmonary bypass of approximately 24% or higher is<br />
associated with higher Psychomotor Development Index<br />
scores <strong>and</strong> reduced lactate levels…..<br />
This study cannot ascerta<strong>in</strong> a universally "safe” hemodilution.
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