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Versus EmtricitabinePlus TDF - HIVandHepatitis.com

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Mean HBV DNA (Log 10 c/mL)<br />

by Baseline LAM-R and Treatment<br />

8<br />

Treatment<br />

Mean HBV DNA (Log 10<br />

Copies/mL)<br />

7<br />

6<br />

5<br />

4<br />

3<br />

2<br />

LLOQ<br />

LAM Res<strong>TDF</strong><br />

Not LAM Res <strong>TDF</strong><br />

LAM ResFTC/<strong>TDF</strong><br />

Not LAM Res FTC/<strong>TDF</strong><br />

1<br />

0 4 8 12 24 36 48 60 72 84 96 108 120 132 144 156 168<br />

Weeks on Study<br />

Not Lam Res FTC/<strong>TDF</strong> N= 46 46 44 46 46 44 44 44 42 40 41 39 38 37 38 38 36<br />

Not Lam Res <strong>TDF</strong> N= 46 46 44 45 45 45 45 44 43 42 43 41 41 39 38 35 37<br />

Lam Res FTC/<strong>TDF</strong> N= 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6<br />

Lam Res <strong>TDF</strong> N= 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7<br />

Gilead Confidential

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