Ian Smith - CMEcorner.com
Ian Smith - CMEcorner.com
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Tumor Ki67 After 4 weeks of Neoadjuvant Endocrine<br />
Therapy for Early Identification of Non-responders<br />
If High Ki67 after 4 weeks<br />
stop endocrine therapy<br />
and switch to chemotherapy<br />
Ellis et al SABCC 2009<br />
BOLERO-2 Phase 3 After an AI:<br />
Exemestane + Everolimus PFS<br />
Probability<br />
of Event (%)<br />
100<br />
80<br />
60<br />
40<br />
HR = 0.36, 95% CI (0.27, 0.47)<br />
Logrank P Value:
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