(PRRT) of Gastro-Entero-Pancreatic NeuroEndocrine Tumors
(PRRT) of Gastro-Entero-Pancreatic NeuroEndocrine Tumors
(PRRT) of Gastro-Entero-Pancreatic NeuroEndocrine Tumors
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Somatostatin Somatostatin Analogues Analogues<br />
octreotide<br />
[Tyr 3 ]octreotide<br />
[Tyr 3 ]octreotate<br />
D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr (ol) (ol)<br />
D-Phe-Cys-Tyr-D-Trp-Lys-Thr-Cys-Thr (ol)<br />
D-Phe-Cys-Tyr-D-Trp-Lys-Thr-Cys-Thr<br />
additional negative charge<br />
DTPA<br />
HOOC-CH 2<br />
H 2 C-COOH<br />
N-(CH 2 ) 2 -N-(CH 2 ) 2 -N<br />
HOOC-CH 2<br />
CH 2 -COOH<br />
CH 2 -COOH<br />
DOTA<br />
HOOC<br />
NN<br />
NN<br />
NN<br />
NN<br />
COOH<br />
stable radiolabeling<br />
with 111 In, 67 Ga, 90 Y, 177 Lu<br />
HOOC<br />
COOH
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