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Arsenic used as fundamental building block<br />

The deadly poison, arsenic,<br />

is used as a building block<br />

for biological molecules such as<br />

those in DNA. Scientists say that<br />

<strong>the</strong> discovery that arsenic is used<br />

by bacterium as a substitute for<br />

phosphorous as it shares similar<br />

properties.<br />

Arsenic has been added to <strong>the</strong><br />

list <strong>of</strong> six elements involved in<br />

<strong>the</strong> chemistry <strong>of</strong> life. The o<strong>the</strong>rs<br />

are oxygen, carbon, hydrogen, nitrogen,<br />

phosphorous and sulphur.<br />

It had been assumed by scientists<br />

that for life to exist it had to contain<br />

<strong>the</strong>se same six elements as<br />

<strong>the</strong> fundamental building blocks<br />

<strong>of</strong> biological molecules.<br />

An arsenic-using microbe<br />

known only by its code name<br />

GFAJ-1 was extracted from<br />

muddy sediment in California’s<br />

Mono Lake, which is naturally<br />

salty and has high concentrations<br />

<strong>of</strong> arsenic in its waters.<br />

Tests have demonstrated that<br />

<strong>the</strong> bacterium actually grows<br />

better when it is exposed to<br />

phosphorous but it appears to be<br />

quite ready to use high concentrations<br />

<strong>of</strong> arsenic in <strong>the</strong> absence<br />

<strong>of</strong> phosphorous.<br />

The study reports that arsenic<br />

in <strong>the</strong> form <strong>of</strong> arsenate can make<br />

<strong>the</strong> appropriate chemical bonds<br />

with carbon and oxygen to act<br />

as a substitute for <strong>the</strong> phosphate<br />

molecule normally found in DNA<br />

and o<strong>the</strong>r biological molecules.<br />

Sophisticated analytical techniques<br />

have shown that <strong>the</strong> arsenic<br />

was incorporated into <strong>the</strong><br />

proteins, lipids, nucleic acids and<br />

o<strong>the</strong>r vital molecules found inside<br />

living cells.<br />

The discovery has vindicated a<br />

<strong>the</strong>ory put forward by Dr Felisa<br />

Wolf-Simon <strong>of</strong> <strong>the</strong> Nasa Astrobiology<br />

Institute in 2006, which<br />

suggested that primitive life<br />

forms on Earth may have used<br />

arsenic as building block. She<br />

suggests that similar microbes<br />

may still exist in some extreme<br />

environments on Earth.<br />

She says that <strong>the</strong> findings<br />

show that <strong>the</strong> requirements for<br />

life could be much more flexible<br />

than had been assumed in <strong>the</strong><br />

past.<br />

W<br />

Watt’s Science<br />

Anti-hydrogen atom found at CERN<br />

European scientists have been able to<br />

capture anti-hydrogen atoms in a novel<br />

magnetic trap and <strong>the</strong>y might now be on<br />

track to unlock <strong>the</strong> mysteries <strong>of</strong> anti-matter<br />

that have puzzled scientists for a long time.<br />

Anti-matter is a subject <strong>of</strong> intense speculation<br />

in <strong>the</strong> global scientific community because<br />

it has been cited as a potential source<br />

<strong>of</strong> boundless and almost cost-free energy.<br />

CERN, <strong>the</strong> European Organisation for<br />

Nuclear Research made <strong>the</strong> announcement<br />

just a few weeks after ano<strong>the</strong>r group working<br />

on <strong>the</strong> same problem said that <strong>the</strong>y had<br />

made and caught elusive anti-matter atoms<br />

for <strong>the</strong> first time.<br />

Yasunori Yamazaki, a member <strong>of</strong> <strong>the</strong><br />

team that trapped <strong>the</strong> anti-hydrogen atom<br />

says that anti-matter will not be able to hide<br />

from researchers for much longer.<br />

It is believed that anti-matter was created<br />

in <strong>the</strong> same quantities as conventional<br />

matter when <strong>the</strong> Big Bang occurred about<br />

13,7-billion years ago.<br />

In a separate announcement, CERN has<br />

announced that it will be closing down its<br />

Large Hadron Collider for two months after<br />

it has had an unbroken stint <strong>of</strong> eight months<br />

<strong>of</strong> scientific research.<br />

CERN’s director-general, Rolf Geuer, says<br />

that <strong>the</strong> scientific discoveries have been rolling<br />

in so fast that <strong>the</strong> LHC’s operation will<br />

be stretched to at least 2012, a year longer<br />

than originally planned.<br />

Apparently it was in <strong>the</strong> LHC that 38<br />

anti-hydrogen atoms were captured in flight<br />

and held for a fleeting moment so that initial<br />

observations <strong>of</strong> <strong>the</strong>ir properties could be<br />

made.<br />

New equipment developed by Asacusa,<br />

Alpha and Atrap overcame <strong>the</strong> problems<br />

that had prevented <strong>the</strong> close study <strong>of</strong> antiparticles.<br />

<strong>November</strong> <strong>2010</strong> 35

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